Výsledky vyhledávání - "Cassandra L. Roeske"

Expression of murine muscle-enriched A-type lamin-interacting protein (MLIP) is regulated by tissue-specific alternative transcription start sites

Autor: Esther Mak, Jonathan J. Weldrick, Gayashan Tennakoon, Patrick G. Burgon, Rishi B Gupta, Marie-Elodie Cattin, Shelley A. Deeke, Sarah A. Dick, Cassandra L. Roeske, Lynn A. Megeney, Zachary J.A. Verret-Borsos

Publikováno v: Journal of Biological Chemistry. 293:19761-19770

Muscle-enriched lamin-interacting protein (Mlip) is an alternatively spliced gene whose splicing specificity is dictated by tissue type. MLIP is most abundantly expressed in brain, cardiac, and skeletal muscle. In the present study, we systematically

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b5b26360c62e65d97cfe40cc9f3a74
https://doi.org/10.1074/jbc.ra118.003758

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Deletion of MLIP (Muscle-enriched A-type Lamin-interacting Protein) Leads to Cardiac Hyperactivation of Akt/Mammalian Target of Rapamycin (mTOR) and Impaired Cardiac Adaptation

Autor: Patrick G. Burgon, Jessica Wang, Marie-Elodie Cattin, Esther Mak, Jonathan J. Weldrick, Aldon J. Lusis, Jean N. DaSilva, Stephanie Thorn, Yibin Wang, Cassandra L. Roeske

Publikováno v: The Journal of biological chemistry, vol 290, iss 44

Aging and diseases generally result from tissue inability to maintain homeostasis through adaptation. The adult heart is particularly vulnerable to disequilibrium in homeostasis because its regenerative abilities are limited. Here, we report that MLI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc5d24c9cea13fad010efd5dd00f830
https://doi.org/10.1074/jbc.m115.678433

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