Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cassandra L. Moyer"'
Autor:
Jing Qian, Yanxia Ma, William M. Tahaney, Cassandra L. Moyer, Amanda Lanier, Jamal Hill, Darian Coleman, Negar Koupaei, Susan G. Hilsenbeck, Michelle I. Savage, Brent D. G. Page, Abhijit Mazumdar, Powel H. Brown
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-16 (2024)
Abstract Background The most aggressive form of breast cancer is triple-negative breast cancer (TNBC), which lacks expression of the estrogen receptor (ER) and progesterone receptor (PR), and does not have overexpression of the human epidermal growth
Externí odkaz:
https://doaj.org/article/c5475652d5314c798be163d273eb4871
Autor:
Jing Qian, Yanxia Ma, William M. Tahaney, Cassandra L. Moyer, Amanda Lanier, Jamal Hill, Darian Coleman, Negar Koupaei, Susan G. Hilsenbeck, Michelle I. Savage, Brent D. G. Page, Abhijit Mazumdar, Powel H. Brown
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/b3912f9d1d094f96a4a647202d931fca
Autor:
Cassandra L. Moyer, Powel H. Brown
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Advancements in research have led to the steady decline of breast cancer mortality over the past thirty years. However, breast cancer incidence has continued to rise, resulting in an undue burden on healthcare costs and highlighting a great need for
Externí odkaz:
https://doaj.org/article/05df759f5ca54dd0b1e980b940ae8810
Autor:
Paul J. Goodfellow, Elizabeth M. Swisher, Scott H. Kaufmann, Marcy E. Richardson, Marc R. Radke, Rachel Doberstein, Jessica L. Gillespie, Jennifer Ivanovich, Cassandra L. Moyer
ClinVar variant interpretations from May 2019 for variants identified in discovery cohorts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acac057c05e3c502ec6ba3d2d14ca576
https://doi.org/10.1158/0008-5472.22424931
https://doi.org/10.1158/0008-5472.22424931
Autor:
Paul J. Goodfellow, Elizabeth M. Swisher, Scott H. Kaufmann, Marcy E. Richardson, Marc R. Radke, Rachel Doberstein, Jessica L. Gillespie, Jennifer Ivanovich, Cassandra L. Moyer
Germline loss-of-function mutations in BRCA1 interacting protein C-terminal helicase 1 (BRIP1) are associated with ovarian carcinoma and may also contribute to breast cancer risk, particularly among patients who develop disease at an early age. Norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34499b081859271be2838c501e8fae51
https://doi.org/10.1158/0008-5472.c.6511902.v1
https://doi.org/10.1158/0008-5472.c.6511902.v1
Autor:
Paul J. Goodfellow, Elizabeth M. Swisher, Scott H. Kaufmann, Marcy E. Richardson, Marc R. Radke, Rachel Doberstein, Jessica L. Gillespie, Jennifer Ivanovich, Cassandra L. Moyer
Supplementary methods; FS1: BRIP1 nonsense and frameshift mutations; FS2: BRIP1 expression in CRISPR cell lines; FS3: hydroxyurea and TMPyP4 challenge; FS4: HEK293TN CRISPR cell lines; FS5: HeLa stable clone rescues; FS6: Transient rescue screening a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af6b2e903081893e9042748bb7176ad
https://doi.org/10.1158/0008-5472.22424934
https://doi.org/10.1158/0008-5472.22424934
Autor:
William M Tahaney, Jing Qian, Reid Powell, Cassandra L Moyer, Yanxia Ma, Nghi Nguyen, Jamal Hill, Clifford Stephan, Abhijit Mazumdar, Peter JA Davies, Powel H Brown
Publikováno v:
Cancer Research. 82:GS1-09
Background: Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype characterized by lack of ER, PR, and Her2. Up to 85% of TNBCs have a p53 mutation as their oncogenic driver. TP53 is a tumor suppressor known as the “guardian o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::500914ec316b00ef311ad28b9313faed
https://doi.org/10.1158/1538-7445.sabcs21-gs1-09
https://doi.org/10.1158/1538-7445.sabcs21-gs1-09
Autor:
William M. Tahaney, Jing Qian, Cassandra L. Moyer, Nghi Nguyen, Amanda Lanier, Yanxia Ma, Jamal Hill, Reid T. Powell, Clifford C. Stephan, Abhijit Mazumdar, Peter J.A. Davies, Powel H. Brown
Background Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer, characterized high rates of tumor protein 53 (p53) mutation and limited targeted therapies. Despite being clinically advantageous, direct targeting of mutant p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::767c3fa2441ebb9ed060c81dcb6e9d9d
https://doi.org/10.21203/rs.3.rs-1547583/v1
https://doi.org/10.21203/rs.3.rs-1547583/v1
Autor:
Marc R. Radke, Elizabeth M. Swisher, Cassandra L. Moyer, Jessica L. Gillespie, Paul J. Goodfellow, Rachel Doberstein, Jennifer Ivanovich, Scott H. Kaufmann, Marcy E. Richardson
Publikováno v:
Cancer Research. 80:857-867
Germline loss-of-function mutations in BRCA1 interacting protein C-terminal helicase 1 (BRIP1) are associated with ovarian carcinoma and may also contribute to breast cancer risk, particularly among patients who develop disease at an early age. Norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3cd4777bf9d10aa7d881d4f715f9239
https://doi.org/10.1158/0008-5472.can-19-1991
https://doi.org/10.1158/0008-5472.can-19-1991
Autor:
Cassandra L, Moyer, Jennifer, Ivanovich, Jessica L, Gillespie, Rachel, Doberstein, Marc R, Radke, Marcy E, Richardson, Scott H, Kaufmann, Elizabeth M, Swisher, Paul J, Goodfellow
Publikováno v:
Cancer Res
Germline loss-of-function mutations in BRIP1 are associated with ovarian carcinoma and may also contribute to breast cancer risk, particularly among patients who develop disease at an early age. Normal BRIP1 activity is required for DNA interstrand c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d62b007e4e3cfdff32167b43ab36e41
https://pubmed.ncbi.nlm.nih.gov/31822495
https://pubmed.ncbi.nlm.nih.gov/31822495