Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cassandra L Buchheit"'
Autor:
Kelsey J Weigel, Laura Rues, Edward J Doyle, Cassandra L Buchheit, John G Wood, Ryan J Gallagher, Laura E Kelly, Jeffrey D Radel, Kenneth A Bradley, Steven M LeVine
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40126 (2012)
Host allelic variation controls the response to B. anthracis and the disease course of anthrax. Mouse strains with macrophages that are responsive to anthrax lethal toxin (LT) show resistance to infection while mouse strains with LT non-responsive ma
Externí odkaz:
https://doaj.org/article/e3e03dd1f2b84491bdd645cb3a0191e4
Oncogenic Ras differentially regulates metabolism and anoikis in extracellular matrix-detached cells
Autor:
Cassandra L. Buchheit, Sienna M. Durbin, Daniel J. Pape, Chelsea McCallister, C A Davison-Versagli, Siyuan Zhang, Joshua A. Mason, Zachary T. Schafer, Amy K. Leliaert, J Zuo
Publikováno v:
Cell Death & Differentiation. 23:1271-1282
In order for cancer cells to survive during metastasis, they must overcome anoikis, a caspase-dependent cell death process triggered by extracellular matrix (ECM) detachment, and rectify detachment-induced metabolic defects that compromise cell survi
Publikováno v:
Nature Reviews Cancer. 14:632-641
Epithelial cells require attachment to the extracellular matrix (ECM) for survival. However, during tumour progression and metastasis, cancerous epithelial cells must adapt to and survive in the absence of ECM. During the past 20 years, several cellu
Publikováno v:
Journal of Neurochemistry. 120:7-25
Iron, an essential element used for a multitude of biochemical reactions, abnormally accumulates in the central nervous system of patients with multiple sclerosis (MS). The mechanisms of abnormal iron deposition in MS are not fully understood, nor do
Autor:
Zachary T. Schafer, Cassandra L. Buchheit, Kelsey J. Weigel, Brittany Angarola, Allison Steiner
Publikováno v:
Cell death and differentiation. 22(8)
Inflammatory breast cancer (IBC) is a rare and highly invasive type of breast cancer, and patients diagnosed with IBC often face a very poor prognosis. IBC is characterized by the lack of primary tumor formation and the rapid accumulation of cancerou
Publikováno v:
Seminars in celldevelopmental biology. 23(4)
The metastasis of cancer cells to distant sites is responsible for the vast majority of cancer mortalities yet the molecular mechanisms underlying this extraordinarily complicated process have yet to be sufficiently elucidated. Recently, it has becom
Publikováno v:
Journal of neurochemistry. 120(1)
Iron, an essential element used for a multitude of biochemical reactions, abnormally accumulates in the central nervous system of patients with multiple sclerosis (MS). The mechanisms of abnormal iron deposition in MS are not fully understood, nor do
Autor:
Cassandra L. Buchheit, Amy K. Leliaert, Sienna M. Durbin, Joshua A. Mason, Calli Versagli, Zachary T. Schafer
Publikováno v:
Cancer Research. 75:2148-2148
In order for successful metastasis to occur, cells must overcome anoikis, a caspase-dependent cell death process triggered by detachment from the extracellular matrix (ECM). In addition, recent studies have revealed that ECM-detached cells must also
Autor:
Kelsey J. Weigel, Zachary T. Schafer, Cassandra L. Buchheit, Brittany Angarola, Allison Steiner
Publikováno v:
Cancer Research. 75:1268-1268
Inflammatory breast cancer (IBC) is a rare and highly invasive type of breast cancer, and patients diagnosed with IBC often face a very poor prognosis. IBC is characterized by the lack of primary tumor formation and the rapid accumulation of cancerou
BIM-EL localization: The key to understanding anoikis resistance in inflammatory breast cancer cells
Publikováno v:
Molecular & Cellular Oncology
Inflammatory breast cancer (IBC) is a highly metastatic and rare type of breast cancer, accounting for 2–6% of newly diagnosed breast cancer cases each year. The highly metastatic nature of IBC cells remains poorly understood. Here we describe our