Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cassandra L, Happe"'
Autor:
Kevin Tenerelli, Robert S. Ross, Chao Chen, Kirk L. Peterson, Nicholas J. Schork, Elie Farah, Ana Maria Manso, Ju Chen, Adam J. Engler, Qian Peng, Nancy D. Dalton, Dekker C. Deacon, Yusu Gu, Neil Tedeschi, Eric Adler, Ting Li, Vivien D. Tran, Neil C. Chi, Cassandra L. Happe
Publikováno v:
Nature Biomedical Engineering. 3:147-157
Dilated cardiomyopathy (DCM) is a leading cause of morbidity and mortality worldwide; yet how genetic variation and environmental factors impact DCM heritability remains unclear. Here, we report that compound genetic interactions between DNA sequence
Autor:
Lian Wong, Yuhong Fan, Basia Gabela-Zuniga, Adam J. Engler, Ashwath Kumar, Kara E. McCloskey, Gagandip Singh, Je Chua, Cassandra L. Happe
Embryonic stem cells (ESC) are excellent cell culture systems for elucidating developmental signals that may be part of the stem cell niche. Although stem cells are traditionally induced using predominately soluble signals, the mechanical environment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63135f0ab458a061befa3b0a5eb2278
https://escholarship.org/uc/item/48d446g3
https://escholarship.org/uc/item/48d446g3
Autor:
Dekker C, Deacon, Cassandra L, Happe, Chao, Chen, Neil, Tedeschi, Ana Maria, Manso, Ting, Li, Nancy D, Dalton, Qian, Peng, Elie N, Farah, Yusu, Gu, Kevin P, Tenerelli, Vivien D, Tran, Ju, Chen, Kirk L, Peterson, Nicholas J, Schork, Eric D, Adler, Adam J, Engler, Robert S, Ross, Neil C, Chi
Publikováno v:
Nature biomedical engineering. 3(2)
Dilated cardiomyopathy (DCM) is a leading cause of morbidity and mortality worldwide; yet how genetic variation and environmental factors impact DCM heritability remains unclear. Here, we report that compound genetic interactions between DNA sequence
Autor:
Vivien D. Tran, Eric Adler, Kevin Tenerelli, Dekker C. Deacon, Hermes Taylor-Weiner, Neil C. Chi, Cassandra L. Happe, Adam J. Engler
Publikováno v:
Circulation Research. 119
Dilated cardiomyopathy (DCM) is a multivariate disease with poorly understood mechanisms, but recently hundreds of variants in 30+ genes have been suggested to contribute to disease pathology. As evidence that two seemingly unrelated heterozygous var
Autor:
Adam J. Engler, Cassandra L. Happe
Publikováno v:
Circulation research, vol 118, iss 2
Happe, CL; & Engler, AJ. (2016). Mechanical Forces Reshape Differentiation Cues That Guide Cardiomyogenesis. CIRCULATION RESEARCH, 118(2), 296-310. doi: 10.1161/CIRCRESAHA.115.305139. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/01f8983m
Happe, CL; & Engler, AJ. (2016). Mechanical Forces Reshape Differentiation Cues That Guide Cardiomyogenesis. CIRCULATION RESEARCH, 118(2), 296-310. doi: 10.1161/CIRCRESAHA.115.305139. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/01f8983m
Soluble morphogen gradients have long been studied in the context of heart specification and patterning. However, recent data have begun to challenge the notion that long-standing in vivo observations are driven solely by these gradients alone. Evide
Autor:
Xinyan Tracy Cui, Patrick A. Cody, Cassandra L. Happe, Elaine M. Robbins, Kasey Catt, I. Mitch Taylor
Publikováno v:
Biosensorsbioelectronics. 89(Pt 1)
Dopamine (DA) is a monoamine neurotransmitter responsible for regulating a variety of vital life functions. In vivo detection of DA poses a challenge due to the low concentration and high speed of physiological signaling. Fast scan cyclic voltammetry