Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Cassandra Flügel-Koch"'
Autor:
Arianna Merlini, Michael Haberl, Judith Strauß, Luisa Hildebrand, Nafiye Genc, Jonas Franz, Dmitri Chilov, Kari Alitalo, Cassandra Flügel-Koch, Christine Stadelmann, Alexander Flügel, Francesca Odoardi
Publikováno v:
Nature neuroscience. 25(7)
The meninges, comprising the leptomeninges (pia and arachnoid layers) and the pachymeninx (dura layer), participate in central nervous system (CNS) autoimmunity, but their relative contributions remain unclear. Here we report on findings in animal mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0d7bb7043fcea1e51507bd874be0b3
https://pubmed.ncbi.nlm.nih.gov/35773544
https://pubmed.ncbi.nlm.nih.gov/35773544
Autor:
Matthew Campbell, Joseph M. Sherwood, Elke Lütjen-Drecoll, Lawrence C. S. Tam, Cassandra Flügel-Koch, Colm O'Brien, Deborah Wallace, Anna-Sophia Kiang, Paul S. Cassidy, Ester Reina-Torres, Peter Humphries, Jeffrey O'Callaghan, Darryl R. Overby, W. Daniel Stamer, Marian M. Humphries, Darragh E. Crosbie
Publikováno v:
Human Molecular Genetics
Intraocular pressure (IOP) is maintained as a result of the balance between production of aqueous humour (AH) by the ciliary processes and hydrodynamic resistance to its outflow through the conventional outflow pathway comprising the trabecular meshw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966c41a295e4ceb2c6683ddf2fdd17ec
https://doi.org/10.1093/hmg/ddx028
https://doi.org/10.1093/hmg/ddx028
Autor:
Nils Schweingruber, Christine Stadelmann, Dirk Fitzner, Marta Zagrebelsky, Jens Frahm, Francesca Odoardi, Brit Mollenhauer, Takashi Watanabe, Henrike J. Fischer, Corinna Schlosser, Arianna Merlini, Dmitri Lodygin, Michael Haberl, Moritz Hermann, Cassandra Flügel-Koch, Hsin-Fang Chang, Holger M. Reichardt, Sebastian Kügler, Alexander Flügel, Henrike Körner
Publikováno v:
Nature
The grey matter is a central target of pathological processes in neurodegenerative disorders such as Parkinson’s and Alzheimer’s diseases. The grey matter is often also affected in multiple sclerosis, an autoimmune disease of the central nervous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13727bdf9eac0461bdbb2daa3704992
https://pubmed.ncbi.nlm.nih.gov/31190448
https://pubmed.ncbi.nlm.nih.gov/31190448
Publikováno v:
Ophthalmic and Physiological Optics. 36:13-20
Purpose To describe an anteriorly located system of zonular fibres that could be involved in fine-tuning of accommodation. Methods Forty-six human and 28 rhesus monkey eyes were dissected and special preparations were processed for scanning electron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb13a355817632cc45fbad66b59d0df
https://doi.org/10.1111/opo.12257
https://doi.org/10.1111/opo.12257
Autor:
Hsin-Fang Chang, Marta Zagrebelsky, Michael Haberl, Christine Stadelmann, Jens Frahm, Cassandra Flügel-Koch, Holger M. Reichardt, Takashi Watanabe, Nils Schweingruber, Arianna Merlini, Henrike Körner, Dmitri Lodygin, Moritz Hermann, Corinna Schlosser, Sebastian Kügler, Alexander Flügel, Francesca Odoardi, Henrike J. Fischer, Brit Mollenhauer, Dirk Fitzner
Publikováno v:
Nature. 567:E15-E15
In this Article, owing to an error during the production process, the y-axis label of Fig. 2c should read "Number of Tβ-syn cells" rather than "Number of T1β-syn cells" and the left and right panels of Fig. 4 should be labelled 'a' and 'b', respect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d513a49bdec22715a3df8ff07230503
https://doi.org/10.1038/s41586-019-1047-0
https://doi.org/10.1038/s41586-019-1047-0
Autor:
Darragh E. Crosbie, Anna-Sophia Kiang, Matthew S. Lawrence, Elke Lütjen-Drecoll, Colm O'Brien, Jeffrey O'Callaghan, Kristin Perkumas, Ester Reina-Torres, W. Daniel Stamer, Marian M. Humphries, Joseph M. Sherwood, Matthew Campbell, John J. Callanan, Lawrence C. S. Tam, Darryl R. Overby, Cassandra Flügel-Koch, Peter Humphries, Paul S. Cassidy, A. Thomas Read, C. Ross Ethier
Publikováno v:
Scientific Reports
The juxtacanalicular connective tissue of the trabecular meshwork together with inner wall endothelium of Schlemm’s canal (SC) provide the bulk of resistance to aqueous outflow from the anterior chamber. Endothelial cells lining SC elaborate tight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fc806f8671f157845801d0b0cd1bf6
https://pubmed.ncbi.nlm.nih.gov/28091584
https://pubmed.ncbi.nlm.nih.gov/28091584
Autor:
Martin Vingron, Christian Schläger, Alexander Flügel, Hans Lehrach, Cassandra Flügel-Koch, Claudio Lottaz, Wilfried Nietfeld, Vijay Kumar Ulaganathan, Dmitri Lodygin, Volker Brinkmann, Wolfgang E. F. Klinkert, Klaus Heckelsmiller, Rainer Spang, Joachim W. Ellwart, Hartmut Wekerle, Francesca Odoardi, Mikhail Nosov, Christopher Sie, Kristina Streyl
Publikováno v:
Nature
The blood–brain barrier (BBB) and the environment of the central nervous system (CNS) guard the nervous tissue from peripheral immune cells. In the autoimmune disease multiple sclerosis, myelin-reactive T-cell blasts are thought to transgress the B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7ff6716034bd7c034b134d58ac8c6c
https://doi.org/10.1038/nature11337
https://doi.org/10.1038/nature11337
Autor:
Francesca Odoardi, Ingo Bartholomäus, Naoto Kawakami, Cassandra Flügel-Koch, Alexander Flügel, Wolfgang E. F. Klinkert, Thomas B. Issekutz, Hartmut Wekerle, Djordje Miljković, Christian Schläger, Joachim W. Ellwart
Publikováno v:
Nature. 462:94-98
The tissues of the central nervous system are effectively shielded from the blood circulation by specialized vessels that are impermeable not only to cells, but also to most macromolecules circulating in the blood. Despite this seemingly absolute sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::addffd4ecde76e793a120cc9652a3ca4
https://doi.org/10.1038/nature08478
https://doi.org/10.1038/nature08478
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 247:1643-1649
Mutations in myocilin, a 55–57 kDa secreted glycoprotein, are causative for some forms of primary open-angle glaucoma (POAG). In vitro studies indicate that myocilin can modulate the hydrodynamic outflow resistance in the trabecular meshwork (TM) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10946beb38c8b2d8a374c2a7e709f46f
https://doi.org/10.1007/s00417-009-1152-0
https://doi.org/10.1007/s00417-009-1152-0
Autor:
Cassandra Flügel-Koch, Ulrich Welge-Lussen, Rudolf Fuchshofer, Andreas Ohlmann, Ernst R. Tamm
Publikováno v:
Experimental Eye Research. 79:649-663
Transforming growth factor-beta2 (TGF-beta2) is elevated in the aqueous humor of patients with primary open-angle glaucoma (POAG), and high levels of TGF-beta2 are thought to contribute to the pathogenesis of POAG. Most TGF-beta2 in the eye is presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c790c05e7927d2f52d5b6afce5392d7
https://doi.org/10.1016/j.exer.2004.07.005
https://doi.org/10.1016/j.exer.2004.07.005