Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Cassandra Demarshall"'
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-19 (2020)
Abstract Possession of the ε4 allele of apolipoprotein E (APOE) is the primary genetic risk factor for the sporadic form of Alzheimer’s disease (AD). While researchers have extensively characterized the impact that APOE ε4 (APOE4) has on the susc
Externí odkaz:
https://doaj.org/article/85c3ec866a7b4d63a0ce9bb218832267
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 2, Iss , Pp 100032- (2020)
The present study demonstrates, using human protein microarrays and plasma and cerebrospinal fluid samples obtained pre-surgically and simultaneously from 46 hip fracture repair patients, that CSF exhibits an extraordinarily complex IgG autoantibody
Externí odkaz:
https://doaj.org/article/403a77eab0834a72816c5ae5925342f3
Autor:
Cassandra DeMarshall, Esther Oh, Rahil Kheirkhah, Frederick Sieber, Henrik Zetterberg, Kaj Blennow, Robert G Nagele
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225178 (2019)
Post-operative delirium (POD) is the most common complication following major surgery in non-demented older (>65 y/o) patients. Patients experiencing POD show increased risk for future cognitive decline, including mild cognitive impairment (MCI) and
Externí odkaz:
https://doaj.org/article/92d2cca0de70452d8337aed798d5dfad
Autor:
Eric P Nagele, Min Han, Nimish K Acharya, Cassandra DeMarshall, Mary C Kosciuk, Robert G Nagele
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60726 (2013)
The presence of self-reactive IgG autoantibodies in human sera is largely thought to represent a breakdown in central tolerance and is typically regarded as a harbinger of autoimmune pathology. In the present study, immune-response profiling of human
Externí odkaz:
https://doaj.org/article/16c67cad77854cf8a2a52afafada0fc4
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32383 (2012)
Parkinson's disease (PD), hallmarked by a variety of motor disorders and neurological decline, is the second most common neurodegenerative disease worldwide. Currently, no diagnostic test exists to identify sufferers, and physicians must rely on a co
Externí odkaz:
https://doaj.org/article/820aeca8b17444f0b60b0899a70e8ee2
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23112 (2011)
After decades of Alzheimer's disease (AD) research, the development of a definitive diagnostic test for this disease has remained elusive. The discovery of blood-borne biomarkers yielding an accurate and relatively non-invasive test has been a primar
Externí odkaz:
https://doaj.org/article/14c50a5c20e042b39ef16b574f22143b
Autor:
Abhirup Sarkar, Hao Wu, Eric L. Goldwaser, Mary C. Kosciuk, George A. Godsey, Robert G. Nagele, Nimish K. Acharya, Cassandra DeMarshall
Publikováno v:
Journal of Alzheimer's Disease
Blood-brain barrier (BBB) permeability is a recognized early feature of Alzheimer's disease (AD). In the present study, we examined consequences of increased BBB permeability on the development of AD-related pathology by tracking selected leaked plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25d8d56ed7abf4ab65ac6dcc3081a34
https://doi.org/10.3233/jad-190962
https://doi.org/10.3233/jad-190962
Autor:
Cassandra DeMarshall, Jeffrey Viviano, Sheina Emrani, George Godsey, Abhirup Sarkar, Benjamin Belinka, David Libon, Robert Nagele
Publikováno v:
Innovation in Aging. 6:589-589
AD-related pathological changes begin in the brain long before symptoms emerge. In the present study, we demonstrate the utility of a panel of AD-related autoantibodies capable of detecting AD at the earliest points along the AD continuum, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aca29d3aafc49adffc93f71439b0032
https://doi.org/10.1093/geroni/igac059.2208
https://doi.org/10.1093/geroni/igac059.2208
Publikováno v:
Brain, Behavior, & Immunity-Health
Brain, Behavior, & Immunity-Health, Vol 2, Iss, Pp 100032-(2020)
Brain, Behavior, & Immunity-Health, Vol 2, Iss, Pp 100032-(2020)
The present study demonstrates, using human protein microarrays and plasma and cerebrospinal fluid samples obtained pre-surgically and simultaneously from 46 hip fracture repair patients, that CSF exhibits an extraordinarily complex IgG autoantibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f39057a3651a35eeff852fff4a80591
http://europepmc.org/articles/PMC8474157
http://europepmc.org/articles/PMC8474157
Autor:
Rahil Kheirkhah, Robert G. Nagele, Frederick E. Sieber, Kaj Blennow, Cassandra DeMarshall, Esther S. Oh, Henrik Zetterberg
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 11, p e0225178 (2019)
PLoS ONE, Vol 14, Iss 11, p e0225178 (2019)
Post-operative delirium (POD) is the most common complication following major surgery in non-demented older (>65 y/o) patients. Patients experiencing POD show increased risk for future cognitive decline, including mild cognitive impairment (MCI) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59cdaed9294513668d1476bba03c58f
https://pubmed.ncbi.nlm.nih.gov/31730624
https://pubmed.ncbi.nlm.nih.gov/31730624