Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Cassandra, Thakurdin"'
Autor:
Miruna Georgiana Ghinia Tegla, Diego F Buenaventura, Diana Y Kim, Cassandra Thakurdin, Kevin C Gonzalez, Mark M Emerson
Publikováno v:
eLife, Vol 9 (2020)
During vertebrate retinal development, subsets of progenitor cells generate progeny in a non-stochastic manner, suggesting that these decisions are tightly regulated. However, the gene-regulatory network components that are functionally important in
Externí odkaz:
https://doaj.org/article/d2c99f7af62d478ebe37b66e4da204c2
Autor:
Kwok-Kin Wong, Sylvie Vincent, Rachael Brake, Victor M. Rivera, Haiquan Chen, Francois Gonzalvez, Sittinon Tang, Eleni Papadopoulos, Cassandra Thakurdin, Val Pyon, Hai Hu, Hailin Ding, Yuanwang Pan, Hua Zhang, Fei Li, Theresa E. Baker, Zhendong Gao, Jiehui Deng, David Peng, Jiansheng Wu, Johara Chouitar, Shougen Cao, Kwan Ho Tang, Chengwei Peng, Shengwu Liu, Michael Fitzgerald, Ting Chen, Shuai Li, Han Han
GSEA analysis of mobocertinib and T-DM1 treated tumors versus mobocertinib-only treated tumors Genes involved in "INTERFERON ALPHA RESPONSE", "INFLAMMATORY RESPONSE", "INTERFERON GAMMA RESPONSE", "IL2 STAT5 SIGNALING", "TNFA SIGNALING VIA NFKB" and "
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc292ba115983e2e9d41bf0078c4067
https://doi.org/10.1158/0008-5472.22490195
https://doi.org/10.1158/0008-5472.22490195
Autor:
Kwok-Kin Wong, Sylvie Vincent, Rachael Brake, Victor M. Rivera, Haiquan Chen, Francois Gonzalvez, Sittinon Tang, Eleni Papadopoulos, Cassandra Thakurdin, Val Pyon, Hai Hu, Hailin Ding, Yuanwang Pan, Hua Zhang, Fei Li, Theresa E. Baker, Zhendong Gao, Jiehui Deng, David Peng, Jiansheng Wu, Johara Chouitar, Shougen Cao, Kwan Ho Tang, Chengwei Peng, Shengwu Liu, Michael Fitzgerald, Ting Chen, Shuai Li, Han Han
No targeted treatments are currently approved for HER2 exon 20 insertion–mutant lung adenocarcinoma patients. Mobocertinib (TAK-788) is a potent irreversible tyrosine kinase inhibitor (TKI) designed to target human epidermal growth factor receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3282ae56d3b65e02abbca4ecf45fe434
https://doi.org/10.1158/0008-5472.c.6533114
https://doi.org/10.1158/0008-5472.c.6533114
Autor:
Kwok-Kin Wong, Sylvie Vincent, Rachael Brake, Victor M. Rivera, Haiquan Chen, Francois Gonzalvez, Sittinon Tang, Eleni Papadopoulos, Cassandra Thakurdin, Val Pyon, Hai Hu, Hailin Ding, Yuanwang Pan, Hua Zhang, Fei Li, Theresa E. Baker, Zhendong Gao, Jiehui Deng, David Peng, Jiansheng Wu, Johara Chouitar, Shougen Cao, Kwan Ho Tang, Chengwei Peng, Shengwu Liu, Michael Fitzgerald, Ting Chen, Shuai Li, Han Han
Figure S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b801af9cd01bb649be8ad1b6d441cd
https://doi.org/10.1158/0008-5472.22490216
https://doi.org/10.1158/0008-5472.22490216
Autor:
Kwok-Kin Wong, Adam J. Bass, Cassandra Thakurdin, Ming-Sound Tsao, Christine Ng, Lynette M. Sholl, Joshua D. Campbell, Jiehui Deng, Patrick H. Lizotte, Heather Silver, Roderick T. Bronson, Jie Bin Liu, Yuanwang Pan, Val Pyon, Catríona M. Dowling, Eleni Papadopoulos, Ting Chen, Zhong Wu, Jin Zhou, Hua Zhang, Josephine Hai
qRT-PCR primer sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0608ac0d3bab1f0c48fa41bee7467e7a
https://doi.org/10.1158/1078-0432.22473695.v1
https://doi.org/10.1158/1078-0432.22473695.v1
Autor:
Kwok-Kin Wong, Adam J. Bass, Cassandra Thakurdin, Ming-Sound Tsao, Christine Ng, Lynette M. Sholl, Joshua D. Campbell, Jiehui Deng, Patrick H. Lizotte, Heather Silver, Roderick T. Bronson, Jie Bin Liu, Yuanwang Pan, Val Pyon, Catríona M. Dowling, Eleni Papadopoulos, Ting Chen, Zhong Wu, Jin Zhou, Hua Zhang, Josephine Hai
Purpose:Lung squamous cell carcinoma (LSCC) is a deadly disease for which only a subset of patients responds to immune checkpoint blockade (ICB) therapy. Therefore, preclinical mouse models that recapitulate the complex genetic profile found in patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bac87800c13738d4e838495200f76dd
https://doi.org/10.1158/1078-0432.c.6528578
https://doi.org/10.1158/1078-0432.c.6528578
Autor:
Kwok-Kin Wong, Adam J. Bass, Cassandra Thakurdin, Ming-Sound Tsao, Christine Ng, Lynette M. Sholl, Joshua D. Campbell, Jiehui Deng, Patrick H. Lizotte, Heather Silver, Roderick T. Bronson, Jie Bin Liu, Yuanwang Pan, Val Pyon, Catríona M. Dowling, Eleni Papadopoulos, Ting Chen, Zhong Wu, Jin Zhou, Hua Zhang, Josephine Hai
Figures S1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23829687f6406c6bbc64fcbd6dca3288
https://doi.org/10.1158/1078-0432.22473710
https://doi.org/10.1158/1078-0432.22473710
Autor:
Hua Zhang, Haiquan Chen, Sittinon Tang, Shougen Cao, Yuanwang Pan, Victor M. Rivera, Shuai Li, Fei Li, Kwan Ho Tang, Hai Hu, Chengwei Peng, Francois Gonzalvez, Hailin Ding, Jiehui Deng, Johara Chouitar, Han Han, Sylvie Vincent, Theresa E. Baker, Michael Fitzgerald, Val Pyon, Ting Chen, Zhendong Gao, Rachael L. Brake, Eleni Papadopoulos, David H. Peng, Jiansheng Wu, Cassandra Thakurdin, Kwok-Kin Wong, Shengwu Liu
Publikováno v:
Cancer Research. 81:5311-5324
No targeted treatments are currently approved for HER2 exon 20 insertion–mutant lung adenocarcinoma patients. Mobocertinib (TAK-788) is a potent irreversible tyrosine kinase inhibitor (TKI) designed to target human epidermal growth factor receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f7997759bba1b98f3f10b2c5af242a6
https://doi.org/10.1158/0008-5472.can-21-1526
https://doi.org/10.1158/0008-5472.can-21-1526
Autor:
Aristotelis Tsirigos, Subhadip Mukhopadhyay, Ting Chen, Mark R. Philips, Jiehui Deng, Hailin Ding, Val Pyon, Ian M. Ahearn, Fei Li, Mirna Bulatović, Antonio Marzio, Justin F. Gainor, Shuai Li, Cassandra Thakurdin, Heather Silver, Peter S. Hammerman, David H. Peng, Eli Rothenberg, John V. Heymach, Michele Pagano, Vajira K. Weerasekara, Yuanwang Pan, Hai Hu, Nathanael S. Gray, Charles M. Perou, Aatish Thennavan, Thales Papagiannakopoulos, Han Han, Baishan Jiang, John T. Poirier, Eleni Papadopoulos, Igor Dolgalev, Kwok-Kin Wong, Gordon J. Freeman, Charles M. Rudin, Nabeel Bardeesy, Eric S. Wang, Jie Li
Publikováno v:
Nature cancer
Inactivating mutations in LKB1/STK11 are present in roughly 20% of nonsmall cell lung cancers (NSCLC) and portend poor response to anti-PD-1 immunotherapy. Unexpectedly, we found that LKB1 deficiency correlated with elevated tumor mutational burden (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aafbf6fd4e394c7de9b24b44901bf672
https://pubmed.ncbi.nlm.nih.gov/35122020
https://pubmed.ncbi.nlm.nih.gov/35122020
Autor:
Han, Han, Shuai, Li, Ting, Chen, Michael, Fitzgerald, Shengwu, Liu, Chengwei, Peng, Kwan Ho, Tang, Shougen, Cao, Johara, Chouitar, Jiansheng, Wu, David, Peng, Jiehui, Deng, Zhendong, Gao, Theresa E, Baker, Fei, Li, Hua, Zhang, Yuanwang, Pan, Hailin, Ding, Hai, Hu, Val, Pyon, Cassandra, Thakurdin, Eleni, Papadopoulos, Sittinon, Tang, Francois, Gonzalvez, Haiquan, Chen, Victor M, Rivera, Rachael, Brake, Sylvie, Vincent, Kwok-Kin, Wong
Publikováno v:
Cancer Res
No targeted treatments are currently approved for HER2 exon 20 insertion-mutant lung adenocarcinoma patients. Mobocertinib (TAK-788) is a potent irreversible tyrosine kinase inhibitor (TKI) designed to target human epidermal growth factor receptor 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6a7d5e6cd053681006543a5c3a6881f
https://pubmed.ncbi.nlm.nih.gov/34380634
https://pubmed.ncbi.nlm.nih.gov/34380634