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Autor:
Robert F, Stanley, Richard T, Piszczatowski, Boris, Bartholdy, Kelly, Mitchell, Wendy M, McKimpson, Swathi, Narayanagari, Dagmar, Walter, Tihomira I, Todorova, Cassandra, Hirsch, Hideki, Makishima, Britta, Will, Christine, McMahon, Kira, Gritsman, Jaroslaw P, Maciejewski, Richard N, Kitsis, Ulrich, Steidl
Publikováno v:
The Journal of Experimental Medicine
Stanley et al. show that loss of Nol3 in mice leads to a myeloproliferative phenotype resembling primary myelofibrosis, with activation of JAK–STAT signaling and significant cellular and molecular resemblance to human disease. These findings provid