Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Cassandra, D Belair"'
Autor:
Xin Zhou, Gopika G. Nair, Holger A. Russ, Cassandra D. Belair, Mei-Lan Li, Mayya Shveygert, Matthias Hebrok, Robert Blelloch
Publikováno v:
Stem Cell Reports, Vol 14, Iss 1, Pp 9-20 (2020)
Summary: Differentiation of human embryonic stem cells into pancreatic β cells holds great promise for the treatment of diabetes. Recent advances have led to the production of glucose-responsive insulin-secreting cells in vitro, but resulting cells
Externí odkaz:
https://doaj.org/article/24b90ec89952421982da2c90744377f2
Autor:
Robert Blelloch, Emmanuelle Passegué, Scott C. Kogan, Haijiang Lin, Keegan Q. Barry-Holson, Cassandra D. Belair, Deepa Subramanyam
Supplementary Figures 1-7 from PML-RARα and Dnmt3a1 Cooperate in vivo to Promote Acute Promyelocytic Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35bda3dd13e9777c651d3c4fd9b467fd
https://doi.org/10.1158/0008-5472.22382241
https://doi.org/10.1158/0008-5472.22382241
Autor:
Robert Blelloch, Emmanuelle Passegué, Scott C. Kogan, Haijiang Lin, Keegan Q. Barry-Holson, Cassandra D. Belair, Deepa Subramanyam
The PML-RARα oncogene is the central effector of acute promyelocytic leukemia (APL). PML-RARα physically interacts with epigenetic-modifying enzymes including DNA methyltransferases (Dnmt) to suppress critical downstream targets. Here, we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f76f58a47ea9a06dfafd568be1f6436
https://doi.org/10.1158/0008-5472.c.6500139.v1
https://doi.org/10.1158/0008-5472.c.6500139.v1
Autor:
Courtney M. Mazur, Tamara Alliston, David A. Monteiro, Jason Yang, Cassandra D. Belair, Neha S. Dole, Jihee Yoon, Serra Kaya
Publikováno v:
FASEB J
Organism scale mechanical forces elicit cellular scale changes through coordinated regulation of multiple signaling pathways. The mechanisms by which cells integrate signaling to generate a unified biological response remains a major question in mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19dac56073e0e96924a71b70f8e3235e
https://doi.org/10.1096/fj.202100930
https://doi.org/10.1096/fj.202100930
Autor:
Siao-Yi Wang, Stephen Shiboski, Cassandra D Belair, Matthew R Cooperberg, Jeffrey P Simko, Hubert Stoppler, Janet Cowan, Peter R Carroll, Robert Blelloch
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98597 (2014)
Serum microRNAs hold great promise as easily accessible and measurable biomarkers of disease. In prostate cancer, serum miRNA signatures have been associated with the presence of disease as well as correlated with previously validated risk models. Ho
Externí odkaz:
https://doaj.org/article/6ffc3d26fee94052b3619d4de68b4319
Autor:
Cassandra D. Belair, J. Luke Campos, David A. Monteiro, Serra Kaya, Charles A. Schurman, Neha S. Dole, Tamara Alliston
Publikováno v:
The FASEB Journal
Bone is a dynamic tissue that constantly adapts to changing mechanical demands. The transforming growth factor beta (TGFβ) signaling pathway plays several important roles in maintaining skeletal homeostasis by both coupling the bone‐forming and bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7dbfc9b7520cb7e44a2faed65c7552a
https://doi.org/10.1096/fj.202001998r
https://doi.org/10.1096/fj.202001998r
Autor:
Gopika G. Nair, Cassandra D. Belair, Matthias Hebrok, Robert Blelloch, Mei-Lan Li, Xin Zhou, Mayya Shveygert, Holger A. Russ
Publikováno v:
Stem cell reports, vol 14, iss 1
Stem Cell Reports, Vol 14, Iss 1, Pp 9-20 (2020)
Stem Cell Reports
Stem Cell Reports, Vol 14, Iss 1, Pp 9-20 (2020)
Stem Cell Reports
Summary Differentiation of human embryonic stem cells into pancreatic β cells holds great promise for the treatment of diabetes. Recent advances have led to the production of glucose-responsive insulin-secreting cells in vitro, but resulting cells r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8f8e6dcf3757b5890f17d765718961
https://escholarship.org/uc/item/4343r09j
https://escholarship.org/uc/item/4343r09j
High-throughput, Efficient, and Unbiased Capture of Small RNAs from Low-input Samples for Sequencing
Autor:
Brandon Chu, Robert Blelloch, Jacob W. Freimer, Matthew R. Cooperberg, Tianyi Hu, Cassandra D. Belair
Publikováno v:
Scientific reports, vol 9, iss 1
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
MicroRNAs hold great promise as biomarkers of disease. However, there are few efficient and robust methods for measuring microRNAs from low input samples. Here, we develop a high-throughput sequencing protocol that efficiently captures small RNAs whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d295ec346ecca068374526eb79dda24d
https://escholarship.org/uc/item/67z201qt
https://escholarship.org/uc/item/67z201qt
Autor:
Robert Blelloch, Qi Fu, Anthony Chang, Elizabeth Montabana, Brandon Chu, Cassandra D. Belair, Tianyi Hu, Lawrence Fong, Chien Chun Pai, Mauro Poggio, Ursula E. Lang
Publikováno v:
Cell, vol 177, iss 2
PD-L1 on the surface of tumor cells binds its receptor PD-1 on effector Tcells, thereby suppressing their activity. Antibody blockade of PD-L1 can activate an anti-tumor immune response leading to durable remissions in a subset of cancer patients. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58752d4e2b825a34a1a003d04cdb24a
https://pubmed.ncbi.nlm.nih.gov/30951669
https://pubmed.ncbi.nlm.nih.gov/30951669
Autor:
Christopher C. Benz, Christina Yau, Marc A. Dall'Era, Cassandra D. Belair, Robert Blelloch, Alireza Paikari, Archana Shenoy, Jeff Simko, Felix Moltzahn
Publikováno v:
EMBO reports, vol 16, iss 9
In human prostate cancer, the microRNA biogenesis machinery increases with prostate cancer progression. Here, we show that deletion of the Dgcr8 gene, a critical component of this complex, inhibits tumor progression in a Pten ‐knockout mouse model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e0bc1039f4ed32e3f18277485655e9
https://doi.org/10.15252/embr.201439925
https://doi.org/10.15252/embr.201439925