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Actinomycin D Specifically Reduces Expanded CUG Repeat RNA in Myotonic Dystrophy Models.

Autor: Siboni RB; Institute of Molecular Biology and Department of Chemistry and Biochemistry, University of Oregon, Eugene, OR 97403, USA., Nakamori M; Department of Neurology, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan., Wagner SD; Institute of Molecular Biology and Department of Chemistry and Biochemistry, University of Oregon, Eugene, OR 97403, USA., Struck AJ; Institute of Molecular Biology and Department of Chemistry and Biochemistry, University of Oregon, Eugene, OR 97403, USA., Coonrod LA; Institute of Molecular Biology and Department of Chemistry and Biochemistry, University of Oregon, Eugene, OR 97403, USA., Harriott SA; Department of Chemistry, Reed College, Portland, OR 97202, USA., Cass DM; Department of Chemistry, Reed College, Portland, OR 97202, USA., Tanner MK; Institute of Molecular Biology and Department of Chemistry and Biochemistry, University of Oregon, Eugene, OR 97403, USA., Berglund JA; Institute of Molecular Biology and Department of Chemistry and Biochemistry, University of Oregon, Eugene, OR 97403, USA; Department of Biochemistry & Molecular Biology, Center for NeuroGenetics, College of Medicine, University of Florida, Gainesville, FL 32610, USA. Electronic address: aberglund@ufl.edu.

Publikováno v: Cell reports [Cell Rep] 2015 Dec 22; Vol. 13 (11), pp. 2386-2394. Date of Electronic Publication: 2015 Dec 10.

The SF3b155 N-terminal domain is a scaffold important for splicing.

Autor: Cass DM; Department of Chemistry and Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403, USA., Berglund JA

Publikováno v: Biochemistry [Biochemistry] 2006 Aug 22; Vol. 45 (33), pp. 10092-101.