Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Casper Soendenbroe"'
Autor:
Casper Soendenbroe, Anders Karlsen, Rene B. Svensson, Michael Kjaer, Jesper L. Andersen, Abigail L. Mackey
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 1, Pp 306-318 (2024)
Abstract Background Age‐related loss of strength is disproportionally greater than the loss of mass, suggesting maladaptations in the neuro‐myo‐tendinous system. Myofibers are often misshaped in aged and diseased muscle, but systematic analyses
Externí odkaz:
https://doaj.org/article/421ada3c85714261a1e3b01109187bb9
Autor:
Michal Tamáš, Stanislava Pankratova, Peter Schjerling, Casper Soendenbroe, Ching‐Yan Chloé Yeung, Cristian Pablo Pennisi, Jens R. Jakobsen, Michael R. Krogsgaard, Michael Kjaer, Abigail L. Mackey
Publikováno v:
Physiological Reports, Vol 9, Iss 21, Pp n/a-n/a (2021)
Abstract Insight into the bidirectional signaling between primary human myogenic cells and neurons is lacking. For this purpose, human myogenic cells were derived from the semitendinosus and gracilis muscles of five healthy individuals and co‐cultu
Externí odkaz:
https://doaj.org/article/74cb20f03038431e9c90762e3b383d57
Autor:
Casper Soendenbroe, Cecilie J. L. Bechshøft, Mette F. Heisterberg, Simon M. Jensen, Emma Bomme, Peter Schjerling, Anders Karlsen, Michael Kjaer, Jesper L. Andersen, Abigail L. Mackey
Publikováno v:
Cells, Vol 9, Iss 4, p 893 (2020)
The decline in muscle mass and function with age is partly caused by a loss of muscle fibres through denervation. The purpose of this study was to investigate the potential of exercise to influence molecular targets involved in neuromuscular junction
Externí odkaz:
https://doaj.org/article/249caa572f7746798ebf1054820408e5
Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption
Autor:
Christopher T.A. Lewis, Lee Tabrizian, Joachim Nielsen, Jenni Laitila, Thomas N. Beck, Mathilde S. Olsen, Marija M. Ognjanovic, Per Aagaard, Rune Hokken, Simon Laugesen, Arthur Ingersen, Jesper L. Andersen, Casper Soendenbroe, Jørn W. Helge, Flemming Dela, Steen Larsen, Ronni E. Sahl, Tue Rømer, Mikkel T. Hansen, Jacob Frandsen, Charlotte Suetta, Julien Ochala
Publikováno v:
Lewis, C T A, Tabrizian, L, Nielsen, J, Laitila, J, Beck, T N, Olsen, M S, Ognjanovic, M M, Aagaard, P, Hokken, R, Laugesen, S, Ingersen, A, Andersen, J L, Soendenbroe, C, Helge, J W, Dela, F, Larsen, S, Sahl, R E, Rømer, T, Hansen, M T, Frandsen, J, Suetta, C & Ochala, J 2023, ' Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption ', The Journal of general physiology, vol. 155, no. 7, e202213268 . https://doi.org/10.1085/jgp.202213268
It has recently been established that myosin, the molecular motor protein, is able to exist in two conformations in relaxed skeletal muscle. These conformations are known as the super-relaxed (SRX) and disordered-relaxed (DRX) states and are finely b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9e4ec0333a12be8ea398773644c26d
https://doi.org/10.1085/jgp.202213268
https://doi.org/10.1085/jgp.202213268
Autor:
Casper Soendenbroe, Christopher L. Dahl, Christopher Meulengracht, Michal Tamáš, Rene B. Svensson, Peter Schjerling, Michael Kjaer, Jesper L. Andersen, Abigail L. Mackey
Publikováno v:
Soendenbroe, C, Dahl, C L, Meulengracht, C, Tamáš, M, Svensson, R B, Schjerling, P, Kjaer, M, Andersen, J L & Mackey, A L 2022, ' Preserved stem cell content and innervation profile of elderly human skeletal muscle with lifelong recreational exercise ', The Journal of Physiology, vol. 600, no. 8, pp. 1969-1989 . https://doi.org/10.1113/JP282677
Muscle fibre denervation and declining numbers of muscle stem (satellite) cells are defining characteristics of ageing skeletal muscle. The aim of this study was to investigate the potential for lifelong recreational exercise to offset muscle fibre d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e4803d382ced243024ead971955f29
https://doi.org/10.1113/jp282677
https://doi.org/10.1113/jp282677
Autor:
Christopher T. A. Lewis, Lee Tabrizian, Joachim Nielsen, Jenni Laitila, Thomas N. Beck, Per Aagaard, Rune Hokken, Simon Laugesen, Arthur Ingersen, Jesper L. Andersen, Casper Soendenbroe, Jørn W. Helge, Flemming Dela, Steen Larsen, Ronni E. Sahl, Tue Rømer, Mikkel T. Hansen, Jacob Frandsen, Charlotte Suetta, Julien Ochala
It has recently been established that myosin, the molecular motor protein, is able to exist in two conformations in relaxed skeletal muscle. These conformations are known as super-relaxed (SRX) and disordered-relaxed (DRX) states and are finely balan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10316d6c646c162d540c9f1112faf33a
https://doi.org/10.1101/2022.09.23.509202
https://doi.org/10.1101/2022.09.23.509202
Autor:
Casper Soendenbroe
Publikováno v:
Soendenbroe, C 2022, ' Neuromuscular function in experimental disuse – a prime suspect? ', Journal of Physiology, vol. 600, no. 21, pp. 4539-4540 . https://doi.org/10.1113/JP283800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294869859e3389841ebcbc87fcef4b87
https://pubmed.ncbi.nlm.nih.gov/36071599
https://pubmed.ncbi.nlm.nih.gov/36071599
Publikováno v:
Tsuchiya, Y, Bayer, M L, Schjerling, P, Soendenbroe, C & Kjaer, M 2022, ' Human derived tendon cells contribute to myotube formation in vitro ', Experimental Cell Research, vol. 417, no. 1, 113164 . https://doi.org/10.1016/j.yexcr.2022.113164
Skeletal muscle possesses remarkable adaptability to mechanical loading and regenerative potential following muscle injury primarily due to satellite cell activity. Although the roles of several types of interstitial cells in skeletal muscle have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7433a916388af3d1d31d7060fc10fc1
https://pubmed.ncbi.nlm.nih.gov/35526568
https://pubmed.ncbi.nlm.nih.gov/35526568
Autor:
Tomas Schmauck-Medina, Adrian Molière, Sofie Lautrup, Jianying Zhang, Stefan Chlopicki, Helena Borland Madsen, Shuqin Cao, Casper Soendenbroe, Els Mansell, Mark Bitsch Vestergaard, Zhiquan Li, Yosef Shiloh, Patricia L. Opresko, Jean-Marc Egly, Thomas Kirkwood, Eric Verdin, Vilhelm A. Bohr, Lynne S. Cox, Tinna Stevnsner, Lene Juel Rasmussen, Evandro F. Fang
Publikováno v:
Schmauck-Medina, T, Molière, A, Lautrup, S, Zhang, J, Chlopicki, S, Madsen, H B, Cao, S, Soendenbroe, C, Mansell, E, Vestergaard, M B, Li, Z, Shiloh, Y, Opresko, P L, Egly, J M, Kirkwood, T, Verdin, E, Bohr, V A, Cox, L S, Stevnsner, T, Rasmussen, L J & Fang, E F 2022, ' New hallmarks of ageing : a 2022 Copenhagen ageing meeting summary ', Aging, vol. 14, no. 16, pp. 6829-6839 . https://doi.org/10.18632/aging.204248
Genomic instability, telomere attrition, epigenetic alterations, mitochondrial dysfunction, loss of proteostasis, deregulated nutrient-sensing, cellular senescence, stem cell exhaustion, and altered intercellular communication were the original nine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0561f3f991fdf490afcba5864a09972c
https://curis.ku.dk/ws/files/319877704/aging_v14i16_204248.pdf
https://curis.ku.dk/ws/files/319877704/aging_v14i16_204248.pdf
Autor:
Casper Soendenbroe, Mette F. Heisterberg, Peter Schjerling, Michael Kjaer, Jesper L. Andersen, Abigail L. Mackey
Publikováno v:
Soendenbroe, C, Flindt Heisterberg, M F, Schjerling, P, Kjaer, M, Andersen, J L & Mackey, A L 2022, ' Human skeletal muscle acetylcholine receptor gene expression in elderly males performing heavy resistance exercise ', American journal of physiology. Cell physiology, vol. 323, pp. C159–C169 . https://doi.org/10.1152/ajpcell.00365.2021
Muscle fiber denervation is a major contributor to the decline in muscle mass and function during aging. Heavy resistance exercise is an effective tool for increasing muscle mass and strength, but whether it can rescue denervated muscle fibers remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4361c371ba34428470139bde915f346
https://curis.ku.dk/ws/files/329416880/PELU_ajpcell.00365.2021.pdf
https://curis.ku.dk/ws/files/329416880/PELU_ajpcell.00365.2021.pdf