Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Casper Skjærbæk"'
Autor:
Tatyana D. Fedorova, Karoline Knudsen, Thorsten K. Rasmussen, Jacob Horsager, Adjmal Nahimi, Casper Skjærbæk, Eva Schaeffer, Daniela Berg, Astrid J. Terkelsen, Per Borghammer
Publikováno v:
IBRO Neuroscience Reports, Vol 14, Iss , Pp 342-345 (2023)
Thyroid [123I]MIBG uptake is proposed as a tool for differentiating between Parkinson’s disease (PD) and diabetes mellitus (DM) on [123I]MIBG scintigraphies since both patient groups show decreased cardiac uptake. One study compared thyroid [123I]M
Externí odkaz:
https://doaj.org/article/d2fa5d4fb84642daabee7e05aad0318a
Autor:
Per Borghammer, Mie Kristine Just, Jacob Horsager, Casper Skjærbæk, Anna Raunio, Eloise H. Kok, Sara Savola, Shigeo Murayama, Yuko Saito, Liisa Myllykangas, Nathalie Van Den Berge
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract The dual-hit hypothesis of Parkinson’s disease (PD) originally postulated that a neurotropic pathogen leads to formation of α-synuclein pathology in the olfactory bulb (OB) and dorsal motor nucleus of the vagus (DMV) and then invades the
Externí odkaz:
https://doaj.org/article/23baeb5a880245f5a53d389e0b383104
Autor:
Niels Okkels, Jacob Horsager, Miguel A. Labrador-Espinosa, Frederik O. Hansen, Katrine B. Andersen, Mie Kristine Just, Tatyana D. Fedorova, Casper Skjærbæk, Ole L. Munk, Kim V. Hansen, Hanne Gottrup, Allan K. Hansen, Michel J. Grothe, Per Borghammer
Publikováno v:
NeuroImage, Vol 269, Iss , Pp 119908- (2023)
Introduction: [18F]fluoroetoxybenzovesamicol ([18F]FEOBV) is a positron emission topography (PET) tracer for the vesicular acetylcholine transporter (VAChT), a protein located predominantly in synaptic vesicles in cholinergic nerve terminals. We aime
Externí odkaz:
https://doaj.org/article/caac9405089a4f35a1aa5b913d872eba
Publikováno v:
Parkinson's Disease, Vol 2022 (2022)
Background. Nonmotor symptoms, including constipation and dysphagia, are very common in Parkinson’s disease (PD) and Lewy pathology is widespread in the gastrointestinal tract, particularly in the lower esophagus. Constipation and REM sleep behavio
Externí odkaz:
https://doaj.org/article/d1fe00144e7645798bace2b93f3d6528
Autor:
Jacob Horsager, Uwe Walter, Tatyana D. Fedorova, Katrine B. Andersen, Casper Skjærbæk, Karoline Knudsen, Niels Okkels, Paul von Weitzel-Mudersbach, Stig Eric Dyrskog, Bo Bergholt, Per Borghammer
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Background: Vagal parasympathetic neurons are prone to degeneration in Parkinson's disease (PD). High-resolution ultrasound can precisely estimate the cross-sectional (CSA) area of peripheral nerves. Here, we tested the hypothesis that vagus CSA is r
Externí odkaz:
https://doaj.org/article/fc6a716c91a340dfbb4f765d3d02866a
Autor:
Martin B. Kinnerup, Michael Sommerauer, Malene F. Damholdt, Jeppe L. Schaldemose, Rola Ismail, Astrid J. Terkelsen, Kristian Stær, Allan Hansen, Tatyana D. Fedorova, Karoline Knudsen, Casper Skjærbæk, Per Borghammer, Nicola Pavese, David J. Brooks, Adjmal Nahimi
Publikováno v:
Neurobiology of Disease, Vol 152, Iss , Pp 105295- (2021)
Noradrenergic neurotransmission may play an important role in tremor modulation through its innervation of key structures of the central tremor circuits. Here, Parkinson's disease (PD) patients with (PDT+) or without (PDT-) rest tremor had 11C-methyl
Externí odkaz:
https://doaj.org/article/09bcadcf9989431db5ce5a4ce09a2016
Autor:
Casper Skjærbæk, Eva Schaeffer, Per Borghammer, Nathalie Van Den Berge, Tatyana D. Fedorova, Katrine B. Andersen, Jacob Horsager, Nicola Pavese, David J. Brooks, Daniela Berg, Karoline Knudsen
Publikováno v:
Knudsen, K, Fedorova, T D, Horsager, J, Andersen, K B, Skjærbæk, C, Berg, D, Schaeffer, E, Brooks, D J, Pavese, N, Van Den Berge, N & Borghammer, P 2021, ' Asymmetric Dopaminergic Dysfunction in Brain-First versus Body-First Parkinson's Disease Subtypes ', Journal of Parkinson's Disease, vol. 11, no. 4, pp. 1677-1687 . https://doi.org/10.3233/JPD-212761
BACKGROUND: We have hypothesized that Parkinson's disease (PD) comprises two subtypes. Brain-first, where pathogenic α-synuclein initially forms unilaterally in one hemisphere leading to asymmetric nigrostriatal degeneration, and body-first with ini
Autor:
Jacob Horsager, Niels Okkels, Tatyana D. Fedorova, Karoline Knudsen, Casper Skjærbæk, Nathalie Van Den Berge, Jan Jacobsen, Ole Lajord Munk, Erik Hvid Danielsen, Dirk Bender, David J. Brooks, Per Borghammer
Publikováno v:
Horsager, J, Okkels, N, Fedorova, T D, Knudsen, K, Skjærbæk, C, Van Den Berge, N, Jacobsen, J, Munk, O L, Danielsen, E H, Bender, D, Brooks, D J & Borghammer, P 2022, ' [ 18F]FEOBV positron emission tomography may not be a suitable method to measure parasympathetic denervation in patients with Parkinson's disease. ', Parkinsonism & Related Disorders, vol. 104, pp. 21-25 . https://doi.org/10.1016/j.parkreldis.2022.09.016
INTRODUCTION: The peripheral autonomic nervous system may be involved years before onset of motor symptoms in some patients with Parkinson's disease (PD). Specific imaging techniques to quantify the cholinergic nervous system in peripheral organs are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c7bffc60050be49a7b2cf0bf96aec4
https://pure.au.dk/portal/da/publications/-18ffeobv-positron-emission-tomography-may-not-be-a-suitable-method-to-measure-parasympathetic-denervation-in-patients-with-parkinsons-disease(2648de38-c902-43af-b117-7baa39c2f326).html
https://pure.au.dk/portal/da/publications/-18ffeobv-positron-emission-tomography-may-not-be-a-suitable-method-to-measure-parasympathetic-denervation-in-patients-with-parkinsons-disease(2648de38-c902-43af-b117-7baa39c2f326).html
Publikováno v:
Abildgaard, L, Oerskov, K M & Skjærbæk, C 2022, Neurologi og evidensbaseret sygepleje . i S Hundborg (red.), Medicinske sygdomme og evidensbaseret sygepleje . FADL's Forlag, København, s. 330-369 .
Aarhus University
Aarhus University
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e1405acdd79c46bbb0be5fd2787d212d
https://pure.au.dk/portal/da/publications/neurologi-og-evidensbaseret-sygepleje(f44d6eeb-90ce-47ea-9eb5-a30468a21cd0).html
https://pure.au.dk/portal/da/publications/neurologi-og-evidensbaseret-sygepleje(f44d6eeb-90ce-47ea-9eb5-a30468a21cd0).html
Autor:
Erik H. Danielsen, Per Borghammer, Malene Flensborg Damholdt, Casper Skjærbæk, Jacob Horsager, David J. Brooks, Anna C. Schacht, Hanne Gottrup, Allan K Hansen, Henriette Klit, Katrine B. Andersen
Publikováno v:
Andersen, K B, Hansen, A K, Damholdt, M F, Horsager, J, Skjaerbaek, C, Gottrup, H, Klit, H, Schacht, A C, Danielsen, E H, Brooks, D J & Borghammer, P 2021, ' Reduced Synaptic Density in Patients with Lewy Body Dementia : An [ 11 C-]UCB-J PET Imaging Study ', Movement Disorders, vol. 36, no. 9, pp. 2057-2065 . https://doi.org/10.1002/mds.28617
BACKGROUND: Patients with Parkinson's disease (PD) often develop dementia, but the underlying substrate is incompletely understood. Generalized synaptic degeneration may contribute to dysfunction and cognitive decline in Lewy body dementias, but in v