Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Casper Paludan"'
Autor:
Martina Vockerodt, Casper Paludan, Dieter Kube, Thomas Tuschl, Dorothee Schmid, Markus Landthaler, Christian Münz
Publikováno v:
Science. 307:593-596
CD4 + T cells classically recognize antigens that are endocytosed and processed in lysosomes for presentation on major histocompatibility complex (MHC) class II molecules. Here, endogenous Epstein-Barr virus nuclear antigen 1 (EBNA1) was found to gai
Autor:
Kiera Goodman, Sarah Nikiforow, Ralph M. Steinman, Casper Paludan, Christian Münz, Kara Bickham, Ming Li Tsang
Publikováno v:
The Journal of Experimental Medicine
The initiation of cell-mediated immunity to Epstein-Barr virus (EBV) has been analyzed with cells from EBV-seronegative blood donors in culture. The addition of dendritic cells (DCs) is essential to prime naive T cells that recognize EBV-latent antig
Autor:
Sarah Nikiforow, Ming L. Tsang, Kara Bickham, Christian Münz, Jean-François Fonteneau, Willem A. Hanekom, Casper Paludan, Stefan Stevanovic, Kiera Goodman
Publikováno v:
The Journal of Immunology. 169:1593-1603
The γ-herpesvirus, EBV, is reliably found in a latent state in endemic Burkitt’s lymphoma. A single EBV gene product, Epstein-Barr nuclear Ag 1 (EBNA1), is expressed at the protein level. Several mechanisms prevent immune recognition of these tumo
Autor:
Ralph M. Steinman, Casper Paludan, Marion Subklewe, Karsten Mahnke, Ming L. Tsang, Christian Münz
Publikováno v:
The Journal of Experimental Medicine
Dendritic cells (DCs) are not targets for infection by the transforming Epstein-Barr virus (EBV). To test if the adjuvant role of DCs could be harnessed against EBV latency genes by cross-presentation, DCs were allowed to process either autologous or
Publikováno v:
The FASEB Journal. 22
Autor:
Marion Subklewe, Anna Roukens, Ralph M. Steinman, Antje Meier, Christian Münz, Casper Paludan, Andrea Block, Jean-François Fonteneau, Kathrin Sebelin
Publikováno v:
Human immunology. 66(9)
Adoptive transfer of Epstein Barr virus (EBV) specific cytotoxic T lymphocytes (CTLs) has been successfully applied in the treatment of EBV associated post-transplant lymphoproliferative disease (PTLD). In most studies EBV transformed B cells (LCLs)
Autor:
Casper Paludan, Christian Münz
Publikováno v:
Current molecular medicine. 3(4)
The human gamma-herpesvirus Epstein-Barr virus establishes latent, life-long infection in more than 95% of the human adult population. Despite its growth transforming capacity, most carriers control EBV associated malignancies efficiently and remain
Autor:
Xiaohua Lu, Lewis Craig M, Chris Lugo, Wu Wei, Matthew Downey, Tara Lakatos, Hemlata Rana, Casper Paludan, Bitao Liang, James W. Edinger, Ryhor Harbacheuski
Publikováno v:
Blood. 110:4112-4112
Placenta Derived Adherent Cells (PDAC) are multipotent progenitor cells derived from human placental tissues. Previously we have reported that PDACs could suppress T-cell proliferation when added to in-vitro mixed lymphocyte reactions (PDAC-MLR) (Pal
Autor:
Qian Ye, Rose Ann Murray, Robert J. Hariri, Jorge H. Soler, James W. Edinger, Wolfgang Hofgartner, Casper Paludan, Gilla Kaplan, Megan Mendillo, Ryhor Harbacheuski, Jia-Lun Wang
Publikováno v:
Blood. 108:1737-1737
The placenta is a readily available and ethically non-controversial source of large amounts of therapeutic stem cells. Placenta Derived Adherent Cells (PDACs) are isolated from the placenta by one of several methods including physical disruption of t
Autor:
Wolfgang Hofgartner, James W. Edinger, Robert J. Hariri, Qian Ye, Casper Paludan, Jia-Lun Wang
Publikováno v:
Blood. 108:1685-1685
The placenta is a rich source of ethically non-controversial stem cells. In this work, we describe the development of procedures to isolate and culture adherent stem cells from a full term, postpartum human placenta (Placenta Derived Adherent Cells,