Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Casper Larsen Barløse"'
Autor:
Casper Larsen Barløse, Jonas Faghtmann, René Slot Bitsch, Joseph Daniel Gbubele, Karl Anker Jørgensen
Publikováno v:
Barløse, C L, Faghtmann, J, Bitsch, R S, Gbubele, J D & Jørgensen, K A 2023, ' Asymmetric Organocatalyzed Cascade Reactions─Merging the pseudo-Halogen and Halogen Effect with Dienamine Catalysis ', Organic Letters, vol. 25, no. 7, pp. 1209-1213 . https://doi.org/10.1021/acs.orglett.3c00220
The combination of asymmetric organocatalysis with the (pseudo)-halogen effect enables the formation of chiral norcarane scaffolds in high yields and selectivities (up to 92% yield, >99% ee, and >95:5 d.r.). This was achieved by reacting (pseudo)-hal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5861320bd9b57b5e028e4be8f1b740f1
https://doi.org/10.1021/acs.orglett.3c00220
https://doi.org/10.1021/acs.orglett.3c00220
Autor:
Vasco Corti, Casper Larsen Barløse, Niklas Lawaetz Østergaard, Anne Kristensen, Nicolaj Inunnguaq Jessen, Karl Anker Jørgensen
Publikováno v:
Corti, V, Barløse, C L, Østergaard, N L, Kristensen, A, Jessen, N I & Jørgensen, K A 2023, ' Organocatalytic Enantioselective Thermal [4 + 4] Cycloadditions ', Journal of the American Chemical Society, vol. 145, no. 2, pp. 1448-1459 . https://doi.org/10.1021/jacs.2c12750
Chiral eight-membered carbocycles are important motifs in organic chemistry, natural product chemistry, chemical biology, and medicinal chemistry. The lack of synthetic methods toward their construction is a challenge preventing their rational design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78520a22798c3cef22b613330d21c7fd
https://doi.org/10.1021/jacs.2c12750
https://doi.org/10.1021/jacs.2c12750
Autor:
David A. McLeod, Mathias Kirk Thøgersen, Casper Larsen Barløse, Mette Louise Skipper, Erlaitz Basabe Obregón, Karl Anker Jørgensen
Publikováno v:
McLeod, D A, Thøgersen, M K, Barløse, C L, Skipper, M L, Obregón, E B & Jørgensen, K A 2022, ' Enantioselective (8+3) Cycloadditions by Activation of Donor–Acceptor Cyclopropanes Employing Chiral Brønsted Base Catalysis ', Angewandte Chemie-International Edition, vol. 61, no. 29, e202206096 . https://doi.org/10.1002/anie.202206096
A novel enantioselective (8+3) cycloaddition between donor–acceptor cyclopropanes and heptafulvenoids catalysed by a chiral bifunctional Brønsted base is described. Importantly, the reaction, which leverages an anionic activation strategy, is dive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c562bf501e026c85696128fcb863771
https://pubmed.ncbi.nlm.nih.gov/35580010
https://pubmed.ncbi.nlm.nih.gov/35580010