Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Casper Larsen"'
Autor:
Casper Larsen, Anders Etzerodt, Mette Madsen, Karsten Skjødt, Søren Kragh Moestrup, Christian Brix Folsted Andersen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Cubilin and the transmembrane protein amnionless (AMN) form the endocytic receptor cubam that is essential for intestinal vitamin B12 uptake. Here the authors present the 2.3 Å crystal structure of AMN in complex with the amino-terminal region of cu
Externí odkaz:
https://doaj.org/article/80fcc40c89f8413ba5eb477b1dfa5777
Publikováno v:
Pharmacy, Vol 7, Iss 2, p 48 (2019)
As the pharmacy profession evolves, good communication skills are vital for securing the safer and more rational use of medicines. Currently there is a lack of qualitative studies researching European student pharmacists’ and their experience with
Externí odkaz:
https://doaj.org/article/cd343b23a9454cb78fb68b3ebdaa6407
Akademický článek
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Autor:
Barløse, Casper Larsen, Faghtmann, Jonas, Kaasik, Mikk, Mastroddi, Roberta, Jørgensen, Karl Anker
Publikováno v:
Organic Letters; 3/1/2024, Vol. 26 Issue 8, p1539-1543, 5p
Autor:
Casper Larsen Barløse, Jonas Faghtmann, René Slot Bitsch, Joseph Daniel Gbubele, Karl Anker Jørgensen
Publikováno v:
Barløse, C L, Faghtmann, J, Bitsch, R S, Gbubele, J D & Jørgensen, K A 2023, ' Asymmetric Organocatalyzed Cascade Reactions─Merging the pseudo-Halogen and Halogen Effect with Dienamine Catalysis ', Organic Letters, vol. 25, no. 7, pp. 1209-1213 . https://doi.org/10.1021/acs.orglett.3c00220
The combination of asymmetric organocatalysis with the (pseudo)-halogen effect enables the formation of chiral norcarane scaffolds in high yields and selectivities (up to 92% yield, >99% ee, and >95:5 d.r.). This was achieved by reacting (pseudo)-hal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5861320bd9b57b5e028e4be8f1b740f1
https://doi.org/10.1021/acs.orglett.3c00220
https://doi.org/10.1021/acs.orglett.3c00220
Autor:
Vasco Corti, Casper Larsen Barløse, Niklas Lawaetz Østergaard, Anne Kristensen, Nicolaj Inunnguaq Jessen, Karl Anker Jørgensen
Publikováno v:
Corti, V, Barløse, C L, Østergaard, N L, Kristensen, A, Jessen, N I & Jørgensen, K A 2023, ' Organocatalytic Enantioselective Thermal [4 + 4] Cycloadditions ', Journal of the American Chemical Society, vol. 145, no. 2, pp. 1448-1459 . https://doi.org/10.1021/jacs.2c12750
Chiral eight-membered carbocycles are important motifs in organic chemistry, natural product chemistry, chemical biology, and medicinal chemistry. The lack of synthetic methods toward their construction is a challenge preventing their rational design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78520a22798c3cef22b613330d21c7fd
https://doi.org/10.1021/jacs.2c12750
https://doi.org/10.1021/jacs.2c12750
Akademický článek
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Akademický článek
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Autor:
Tobias Siefen, John Lokhnauth, Brice Moulari, Yann Pellequer, Alfred Chi-Yeh Liang, Crilles Casper Larsen, Alf Lamprecht, Arnaud Béduneau, Henusha D. Jhundoo, Christoph Schmidt
Publikováno v:
Biomolecules & Therapeutics
5-amino salicylic acid (5-ASA) is a standard therapy for the treatment of mild to moderate forms of inflammatory bowel diseases (IBD) whereas more severe forms involve the use of steroids and immunosuppressive drugs. Hyaluronic acid (HA) is a natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07aa3e8694ee24aba36f27cfdf5b6064
https://doi.org/10.4062/biomolther.2020.227
https://doi.org/10.4062/biomolther.2020.227
Publikováno v:
Journal of Controlled Release. 332:581-591
Estimation of joint residence time of a drug is a key requirement for rational development of intraarticular therapeutics. There is a great need for a predictive model to reduce the high number of animal experiments in early stage development. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f4fe79cbfa247a77cd6bb8259a8c95
https://doi.org/10.1016/j.jconrel.2021.03.008
https://doi.org/10.1016/j.jconrel.2021.03.008