Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Casper GR"'
Autor:
Asbjørn Graver Petersen, Stefanie H. Korntner, Jamal Bousamaki, Denise Oró, Alba Manresa Arraut, Susanne E. Pors, Casper Gravesen Salinas, Maja Worm Andersen, Martin Rønn Madsen, Yaohui Nie, Jordan Butts, Manuel Roqueta‐Rivera, Ulf Simonsen, Henrik H. Hansen, Michael Feigh
Publikováno v:
Physiological Reports, Vol 12, Iss 19, Pp n/a-n/a (2024)
Abstract This study comprehensively validated the bleomycin (BLEO) induced mouse model of IPF for utility in preclinical drug discovery. To this end, the model was rigorously evaluated for reproducible phenotype and TGFβ‐directed treatment outcome
Externí odkaz:
https://doaj.org/article/cb84d450302846dba69d6266991df0ae
Publikováno v:
JMIR mHealth and uHealth, Vol 12, p e50616 (2024)
BackgroundMusculoskeletal diseases affect 1.71 billion people worldwide, impose a high biopsychosocial burden on patients, and are associated with high economic costs. The use of digital health interventions is a promising cost-saving approach for th
Externí odkaz:
https://doaj.org/article/e87c6f9b644b44c59c5e2743248c070d
Autor:
Casper Grønlund Larsen, Mikael Karlberg, Frank Guldfred, Louise Devantier, Mathias Maagaard, Preben Homøe, Bjarki Ditlev Djurhuus
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Menière’s disease is an idiopathic disorder characterized by recurrent episodes of vertigo lasting more than 20 min, unilateral sensorineural hearing loss, and tinnitus. If vertigo attacks occur frequently, the patient is usual
Externí odkaz:
https://doaj.org/article/0e767997ca35416e91abf0f9ef19977d
Autor:
Mathias B. Møllerhøj, Sanne S. Veidal, Kirstine Tølbøl Thrane, Denise Oró, Agnete Overgaard, Casper Gravesen Salinas, Martin Rønn Madsen, Larissa Pfisterer, Mogens Vyberg, Eric Simon, Andre Broermann, Niels Vrang, Jacob Jelsing, Michael Feigh, Henrik H. Hansen
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 5, Pp 1167-1186 (2022)
Abstract Non‐alcoholic steatohepatitis (NASH) has emerged as a major challenge for public health because of high global prevalence and lack of evidence‐based therapies. Most animal models of NASH lack sufficient validation regarding disease progr
Externí odkaz:
https://doaj.org/article/5fe3d3005960450b826f54e82c75529a
Autor:
Urmas Roostalu, Louise Thisted, Jacob Lercke Skytte, Casper Gravesen Salinas, Philip Juhl Pedersen, Jacob Hecksher-Sørensen, Bidda Rolin, Henrik H. Hansen, James G. MacKrell, Robert M. Christie, Niels Vrang, Jacob Jelsing, Nora Elisabeth Zois
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Angiotensin converting enzyme inhibitors, among them captopril, improve survival following myocardial infarction (MI). The mechanisms of captopril action remain inadequately understood due to its diverse effects on multiple signalling pathwa
Externí odkaz:
https://doaj.org/article/5eb67c5b398c476eaf57ac9ff978429a
Autor:
Vanessa Isabell Jurtz, Grethe Skovbjerg, Casper Gravesen Salinas, Urmas Roostalu, Louise Pedersen, Jacob Hecksher-Sørensen, Bidda Rolin, Michael Nyberg, Martijn van de Bunt, Camilla Ingvorsen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Complications of atherosclerosis are the leading cause of morbidity and mortality worldwide. Various genetically modified mouse models are used to investigate disease trajectory with classical histology, currently the preferred methodology t
Externí odkaz:
https://doaj.org/article/307dce623c614724b179921559a4ac86
Autor:
Casper Groth, Pooja Vaid, Aditi Khatpe, Nelchi Prashali, Avantika Ahiya, Diana Andrejeva, Madhumita Chakladar, Sanket Nagarkar, Rachel Paul, Devaki Kelkar, Teresa Eichenlaub, Hector Herranz, TS Sridhar, Stephen M. Cohen, LS Shashidhara
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 2999-3008 (2020)
Genetic approaches in Drosophila have successfully identified many genes involved in regulation of growth control as well as genetic interactions relevant to the initiation and progression of cancer in vivo. Here, we report on large-scale RNAi-based
Externí odkaz:
https://doaj.org/article/e1fb7176b05c46169a5d8e011d094d80
Autor:
Matthias Wilhelm Hoppe, Joana Brochhagen, Thomas Tischer, Knut Beitzel, Romain Seil, Casper Grim
Publikováno v:
Journal of Experimental Orthopaedics, Vol 9, Iss 1, Pp n/a-n/a (2022)
Abstract Purpose The aim of this systematic review was to update the knowledge on risk factors and prevention strategies for shoulder injuries in overhead sports with special emphasis on methodological quality. Methods All methodological procedures w
Externí odkaz:
https://doaj.org/article/d0a537926d934415b3fb23d2d3c03b57
Autor:
Casper Grønlund, Louise Devantier, Henriette Edemann Callesen, Dan Dupont Hougaard, Mina Nicole Händel, Jesper Hvass Schmidt, Frank Liviu-Adelin Guldfred, Bjarki Ditlev Djurhuus
Publikováno v:
International Archives of Otorhinolaryngology, Vol 25, Iss 03, Pp e463-e470 (2021)
Introduction Menière disease (MD) is a disorder characterized by episodes of vertigo, sensorineural hearing loss, tinnitus and aural fullness. Objectives To assess the effect of ventilation tube insertion (VTI) on vertiginous episodes in patients (
Externí odkaz:
https://doaj.org/article/0fef20fea6ea49a5ad7df9441e4eef4b
Autor:
Henrik H. Hansen, Johanna Perens, Urmas Roostalu, Jacob Lercke Skytte, Casper Gravesen Salinas, Pernille Barkholt, Ditte Dencker Thorbek, Kristoffer T.G. Rigbolt, Niels Vrang, Jacob Jelsing, Jacob Hecksher-Sørensen
Publikováno v:
Molecular Metabolism, Vol 47, Iss , Pp 101171- (2021)
Objective: The development of effective anti-obesity therapeutics relies heavily on the ability to target specific brain homeostatic and hedonic mechanisms controlling body weight. To obtain further insight into neurocircuits recruited by anti-obesit
Externí odkaz:
https://doaj.org/article/bd964deac5714ad4a7d015ebc7bd52eb