Antibody-based inhibition of circulating DLK1 protects from estrogen deficiency-induced bone loss in mice

Autor: Karsten Skjødt, Moustapha Kassem, Charlotte Harken Jensen, Søren P. Sheikh, Nicholas Ditzel, Florence Figeac, Casper A. Nipper Nielsen, Basem M. Abdallah, Ditte Caroline Andersen

Publikováno v: Figeac, F, Andersen, D C, Nipper Nielsen, C A, Ditzel, N, Sheikh, S P, Skjødt, K, Kassem, M, Jensen, C H & Abdallah, B M 2018, ' Antibody-based inhibition of circulating DLK1 protects from estrogen deficiency-induced bone loss in mice ', Bone, vol. 110, pp. 312-320 . https://doi.org/10.1016/j.bone.2018.02.030

Soluble delta-like 1 homolog (DLK1) is a circulating protein that belongs to the Notch/Serrate/delta family, which regulates many differentiation processes including osteogenesis and adipogenesis. We have previously demonstrated an inhibitory effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3754b76f7cc73551cea316d4fda0e1
https://doi.org/10.1016/j.bone.2018.02.030