Zobrazeno 1 - 10
of 4 110
pro vyhledávání: '"Caspase-8"'
Autor:
Hideki Kimura, Kazuko Kamiyama, Toru Imamoto, Izumi Takeda, Mamiko Kobayashi, Naoki Takahashi, Kenji Kasuno, Takeshi Sugaya, Masayuki Iwano
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Cisplatin-induced injury to renal proximal tubular cells stems from mitochondrial damage-induced apoptosis and inflammation. Dichloroacetate (DCA), a pyruvate dehydrogenase kinase (PDK) inhibitor, a potential generator of ROS and ATP, protec
Externí odkaz:
https://doaj.org/article/b817c57363ca4a61a060f910d74cccee
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-46 (2024)
Abstract Caspase-8, a renowned cysteine-aspartic protease within its enzyme family, initially garnered attention for its regulatory role in extrinsic apoptosis. With advancing research, a growing body of evidence has substantiated its involvement in
Externí odkaz:
https://doaj.org/article/caf5362eb5474d829b9f0583adeeeee0
Publikováno v:
Nutrition & Metabolism, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Background Breast cancer is the most diagnosed cancer in women. Its pathogenesis includes several pathways in cancer proliferation, apoptosis, and metastasis. Some clinical data have indicated the association between coffee consumption and d
Externí odkaz:
https://doaj.org/article/f9e33028a2eb4691ba67e8a61539e4a9
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 53-61 (2024)
AbstractContext: Berberine (BBR) can regulate enteric glial cells (EGCs) and the gut vascular barrier (GVB).Objective: To explore whether BBR regulates GVB permeability via the S100B pathway.Materials and methods: GVB hyperpermeability in C57BL/6J mi
Externí odkaz:
https://doaj.org/article/27d907631010406ca3796869618b5da6
Autor:
Grigory Demyashkin, Ekaterina Blinova, Migran Grigoryan, Mikhail Parshenkov, Polina Skovorodko, Vladimir Ius, Anastasia Lebed, Petr Shegay, Andrei Kaprin
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8914-8944 (2024)
Epilepsy is one of the most frequently diagnosed neurological diseases, but the neurobiological basis of the disease remains poorly understood. Immunophenotyping CBA mice brain (NeuN and caspase-8) in parallel with hippocampal neurons’ functional s
Externí odkaz:
https://doaj.org/article/4d231900c1a74c6889fb523d1685e48f
Autor:
Slamet Budijanto, Yeni Kurniati, Lilis Nuraida, Fitriya Nur Annisa Dewi, Bambang Pontjo Priosoeryanto, Nancy Dewi Yuliana, Ardiansyah, Uus Saepuloh, Safrida, Hitoshi Shirakawa
Publikováno v:
AIMS Agriculture and Food, Vol 9, Iss 3, Pp 789-800 (2024)
Black rice bran (BRB) is well-known for its high antioxidant activity and its pivotal role in preventing colon cancer. The present study aims to investigate the effects of BRB administration on BALB/C mice induced with azoxymethane (AOM) and dextran
Externí odkaz:
https://doaj.org/article/d04e52accc1e45f082f11bf79c3ce8a7
Publikováno v:
Biosafety and Health, Vol 6, Iss 3, Pp 171-177 (2024)
Enterovirus D68 (EV-D68) infection causes severe acute respiratory infection and severe neurological complications, such as acute flaccid myelitis (AFM), in children. However, although EV-D68 has pandemic potential, no effective drugs or vaccines are
Externí odkaz:
https://doaj.org/article/ac2394b43b864cd99e350680821443dc
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Death receptor (DR) networks are controlled by the assembly of the Death-Inducing Signaling Complex (DISC) and complex II. The family of small molecules FLIPins (FLIP interactors) were developed to target the caspase-8/c-FLIPL heterodimer. FLIPin com
Externí odkaz:
https://doaj.org/article/7aeed166e38d48c38f7c53462df12fb6
Publikováno v:
International Journal of Hyperthermia, Vol 41, Iss 1 (2024)
AbstractBackground Hyperthermia can play a synergistic role with chemotherapy in combination therapy. Although the association between caspase activation, apoptosis, and pyroptosis have been published for both cisplatin (CDDP) and hyperthermia therap
Externí odkaz:
https://doaj.org/article/f67daf8c18fc4684af46bbb43b62249c