Zobrazeno 1 - 10
of 6 618
pro vyhledávání: '"Caspase-1"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Cardiovascular complications pose a significant burden in type 2 diabetes mellitus (T2DM), driven by the intricate interplay of chronic hyperglycemia, insulin resistance, and lipid metabolism disturbances. Myocardial ischemia/reperfusion (MI
Externí odkaz:
https://doaj.org/article/49ae02357d8b4c3985cbcc854f6bda09
Publikováno v:
陆军军医大学学报, Vol 46, Iss 13, Pp 1535-1544 (2024)
Objective To investigate the role of sodium-hyaluronate-modified calcium peroxide nanoparticles (SH-CaO2 NPs) in inducing pyroptosis in human gastric cancer cells and its possible mechanisms. Methods Transmission electron microscopy (TEM), X-ray diff
Externí odkaz:
https://doaj.org/article/7e529fc8e7924bdeaa49c7a677df10f7
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 3839-3864 (2024)
Abdullah Al Mamun,1,2 Chuxiao Shao,1 Peiwu Geng,1 Shuanghu Wang,1 Jian Xiao1– 3 1Central Laboratory of The Lishui Hospital of Wenzhou Medical University, Lishui People’s Hospital, Lishui, Zhejiang, 323000, People’s Republic of China; 2Molecular
Externí odkaz:
https://doaj.org/article/8b6d422fd8ad4444bdfb8e379eff4754
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 3801-3813 (2024)
Wanjun Gu, Qi Zeng, Xin Wang, Huthaifa Jasem, Ling Ma Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of ChinaCorrespondence: Ling Ma, No. 36 Sanhao Street, Heping District, Shenyang, 110004
Externí odkaz:
https://doaj.org/article/f2c736a48f3c49269187ca95f5beb0c2
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 5, Pp 690-698 (2024)
Objective To compare the effectiveness between qPCR and trace-level proteins quantitative analysis in detecting the expression of inflammation-associated factors caspase-1 and IL-1β in peripheral blood monocytes from breast cancer patients. Methods
Externí odkaz:
https://doaj.org/article/463d0e172a2b4332b6c69566efe2c7f3
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 4007-4019 (2024)
Mengyang Li,1,* Yuting Wang,2,* He Liu,2 Xiaonan Huang,2 Huagang Peng,2 Yi Yang,2 Zhen Hu,2 Jianxiong Dou,2 Chuan Xiao,2 Juan Chen,3 Weilong Shang,2 Xiancai Rao1,2 1Department of Microbiology, School of Medicine, Chongqing University, Chongqi
Externí odkaz:
https://doaj.org/article/2752130f92d24264bba7ea892f9aad62
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background Cardiac fibroblasts (CFs) are activated after initial injury, and then differentiate into myofibroblasts (MFs), which play a pivotal role as the primary mediator cells in pathological remodeling. Sodium butyrate (NaB), being a met
Externí odkaz:
https://doaj.org/article/094c8a546b354fb6a6e2e361ff4eb423
Autor:
Camilla Udjus, Bente Halvorsen, Xiang Yi Kong, Ellen Lund Sagen, Marita Martinsen, Kuan Yang, Else Marit Løberg, Geir Christensen, Ole Henning Skjønsberg, Karl‐Otto Larsen
Publikováno v:
Physiological Reports, Vol 12, Iss 14, Pp n/a-n/a (2024)
Abstract Inflammation through activation of caspase‐1, seems to play a role in pulmonary hypertension induced by alveolar hypoxia. Whether alveolar hypoxia induces caspase‐1‐mediated inflammation and influx of leukocytes in other organs than th
Externí odkaz:
https://doaj.org/article/f25c7b58ac1744ec9d818268d473829d
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectiveThis study aimed to evaluate the role of absent in melanoma 2 (AIM2) inflammasome-mediated pyroptosis in the pathogenesis of acute gouty arthritis (AGA) and asymptomatic hyperuricemia(AHU).MethodsA cohort of 30 AGA patients, 30 AHU individua
Externí odkaz:
https://doaj.org/article/afde4ee3af184f0d9238c445e842676a
Autor:
Patrick M. Exconde, Christopher M. Bourne, Madhura Kulkarni, Bohdana M. Discher, Cornelius Y. Taabazuing
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Caspases are a family of cysteine proteases that act as molecular scissors to cleave substrates and regulate biological processes such as programmed cell death and inflammation. Extensive efforts have been made to identify caspase substrates
Externí odkaz:
https://doaj.org/article/94f537e8fab741c980046388fe14e2ad