Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Caspase 3/metabolism"'
Autor:
Ozlem Ozmen, Senay Topsakal
Publikováno v:
Endocrine, Metabolic & Immune Disorders - Drug Targets. 19:1141-1147
Objective: The aim of this study was to examine pancreatic pathology and the prophylactic effects of pregabalin in lipopolysaccharide (LPS) induced sepsis model in aged rats. Methods: Twenty-four female, one-year-old, Wistar Albino rats were assigned
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f9114be52657faf470b2e0452280f8
https://doi.org/10.2174/1871530319666190306095532
https://doi.org/10.2174/1871530319666190306095532
Autor:
Matteo Ferrari, Christian Krapp, Michela Muscolini, Angela Santoni, Martin R. Jakobsen, Alessandra Zevini, Alessandra Zingoni, David Olagnier, John Hiscott, Enrico Palermo, Giovanna Peruzzi, Luciano Castiello, Elisabetta Vulpis
Publikováno v:
Castiello, L, Zevini, A, Vulpis, E, Muscolini, M, Ferrari, M, Palermo, E, Peruzzi, G, Krapp, C, Jakobsen, M, Olagnier, D, Zingoni, A, Santoni, A & Hiscott, J 2019, ' An optimized retinoic acid-inducible gene I agonist M8 induces immunogenic cell death markers in human cancer cells and dendritic cell activation ', Cancer Immunology, Immunotherapy, vol. 68, no. 9, pp. 1479-1492 . https://doi.org/10.1007/s00262-019-02380-2
RIG-I is a cytosolic RNA sensor that recognizes short 5 ' triphosphate RNA, commonly generated during virus infection. Upon activation, RIG-I initiates antiviral immunity, and in some circumstances, induces cell death. Because of this dual capacity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a021b4cf5bcdbe0488874886620a2142
https://doi.org/10.1007/s00262-019-02380-2
https://doi.org/10.1007/s00262-019-02380-2
Beta amyloid plays a main role in the pathophysiology of Alzheimer's disease by inducing oxidative stress in the brain. Curcumin, a natural antioxidant, is known to inhibit beta amyloid and beta amyloid induced oxidative stress. However, low bioavail
Externí odkaz:
http://hdl.handle.net/10454/6112
Autor:
Francis Corazza, David De Bels, Frauke Tillmans, Costantino Balestra, Mariano Bizzari, Peter Germonpré, Keziban Gunce Orman, Peter Radermacher
Publikováno v:
Biomolecules
Biomolecules, 10 (2
Volume 10
Issue 2
Biomolecules, Vol 10, Iss 2, p 282 (2020)
Biomolecules, 10 (2
Volume 10
Issue 2
Biomolecules, Vol 10, Iss 2, p 282 (2020)
Oxygenation conditions are crucial for growth and tumor progression. Recent data suggests a decrease in cancer cell proliferation occurring after exposure to normobaric hyperoxia. Those changes are associated with fractal dimension. The purpose of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88db9696e954dba868cc2c1cd490ec1d
Autor:
Jinglu Ai, R. L. Macdonald, Mervyn D.I. Vergouwen, Shakira Brathwaite, H Ni, Joost C. M. Meijers, H Wan, Yiming Wang, Elly M. Hol
Publikováno v:
Journal of Thrombosis and Haemostasis
Journal of Thrombosis and Haemostasis, 16, 1413-1422. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 16(7), 1413. Wiley-Blackwell
Journal of thrombosis and haemostasis, 16(7), 1413-1422. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 16, 1413-1422. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 16(7), 1413. Wiley-Blackwell
Journal of thrombosis and haemostasis, 16(7), 1413-1422. Wiley-Blackwell
Essentials von Willebrand Factor (VWF) and ADAMTS13 may affect early injury after subarachnoid hemorrhage (SAH). Early brain injury was assessed in VWF−/−, ADAMTS13−/− and recombinant (r) ADAMTS13 treated mice. VWF−/− and rADAMTS13 treate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b5717ba674e50c8f0ea29e47800996
https://doi.org/10.1111/jth.14136
https://doi.org/10.1111/jth.14136
Autor:
Hugues Henry, Olivier Braissant, Sónia do Vale-Pereira, Julijana Ivanisevic, Noémie Remacle, Denise Tavel, Diana Ballhausen, Hong-Phuc Cudré-Cung, Petra Zavadakova
Publikováno v:
Molecular genetics and metabolism, vol. 119, no. 1-2, pp. 57-67
Using 3D organotypic rat brain cell cultures in aggregates we recently identified 2-methylcitrate (2-MCA) as the main toxic metabolite for developing brain cells in methylmalonic aciduria. Exposure to 2-MCA triggered morphological changes and apoptos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d03dd985c8ab99f322eec2b8b7c870b
https://doi.org/10.1016/j.ymgme.2016.07.013
https://doi.org/10.1016/j.ymgme.2016.07.013
AIM: The aim of this study was to investigate the beneficial effects of 18β-glycyrrhetinic acid (GA) on the experimental allergic encephalomyelitis (EAE) in C57BL/6 mice. GA is a natural substance found in the root of licorice and is used in traditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3566::d6d64e4641496deb88dab2608383867b
Autor:
Mohamed Chibane, Gérard Lizard, Amira Zarrouk, Pierre Andreoletti, Samia Hadj-Ahmed, Khodir Madani, Fatiha Brahmi, Lila Boulekbache-Makhlouf, Anne Vejux, Maryem Bezine, Thomas Nury
Publikováno v:
Pharmaceutical Biology
Pharmaceutical Biology, Taylor & Francis, 2017, 55 (1), pp.286-293. 〈10.1080/13880209.2016.1235208〉
Pharmaceutical Biology, Taylor & Francis, 2017, 55 (1), pp.286-293. ⟨10.1080/13880209.2016.1235208⟩
Pharmaceutical Biology, Vol 55, Iss 1, Pp 286-293 (2017)
Scopus-Elsevier
Pharmaceutical Biology, Taylor & Francis, 2017, 55 (1), pp.286-293. 〈10.1080/13880209.2016.1235208〉
Pharmaceutical Biology, Taylor & Francis, 2017, 55 (1), pp.286-293. ⟨10.1080/13880209.2016.1235208⟩
Pharmaceutical Biology, Vol 55, Iss 1, Pp 286-293 (2017)
Scopus-Elsevier
International audience; Context: Mints (Lamiaceae) are used as traditional remedies for the treatment of several diseases. Their extracts are recognized as anti-inflammatory compounds. Objective: This study characterized the cytotoxic effects of Ment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ec80bc4ec1a1d47a2f5aecf14413d9
https://hal.archives-ouvertes.fr/hal-01513649
https://hal.archives-ouvertes.fr/hal-01513649
Autor:
Fabrice Lemaître, Kym R. Garrod, Isabelle Bouvier, Hélène D. Moreau, Matthew L. Albert, Philippe Bousso, Zacarias Garcia
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2012, 2 (5), pp.1438-1447. ⟨10.1016/j.celrep.2012.10.015⟩
Cell Reports, 2012, 2 (5), pp.1438-1447. ⟨10.1016/j.celrep.2012.10.015⟩
Cell Reports, Vol 2, Iss 5, Pp 1438-1447 (2012)
Cell Reports, Elsevier Inc, 2012, 2 (5), pp.1438-1447. ⟨10.1016/j.celrep.2012.10.015⟩
Cell Reports, 2012, 2 (5), pp.1438-1447. ⟨10.1016/j.celrep.2012.10.015⟩
Cell Reports, Vol 2, Iss 5, Pp 1438-1447 (2012)
International audience; Contraction is a critical phase of immunity whereby the vast majority of effector T cells die by apoptosis, sparing a population of long-lived memory cells. Where, when, and why contraction occurs has been difficult to address
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0f375a7580b0fcede81ef688dc2ea6
https://doi.org/10.1016/j.celrep.2012.10.015
https://doi.org/10.1016/j.celrep.2012.10.015
Publikováno v:
Free Radical Biology and Medicine
Free Radical Biology and Medicine, vol. 53, no. 4, pp. 926-935
Free Radical Biology and Medicine, vol. 53, no. 4, pp. 926-935
Peroxynitrite (PN) is a potent nitrating and oxidizing agent generated during various pathological situations affecting the heart. The negative effects of PN result, at least in part, from its ability to activate caspases and apoptosis. RasGAP is a u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d22e768ae207233a8585c4b121490b