Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Caspase 1/genetics"'
Autor:
Heilig, Rosalie, Dilucca, Marisa, Boucher, Dave, Chen, Kaiwen W, Hancz, Dora, Demarco, Benjamin, Shkarina, Kateryna, Broz, Petr
Publikováno v:
Life science alliance, vol. 3, no. 6, pp. e202000735
Life Science Alliance
Life Science Alliance
Caspase-1 activation in GSDMD-deficient cells induces a rapid form of caspase-3–dependent secondary necrosis that is licenced by caspase-1–induced Bid cleavage and the release of mitochondrial SMAC.
Caspase-1 drives a lytic inflammatory cell
Caspase-1 drives a lytic inflammatory cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::62127aa98cc87afb0c61f23f2bbacbad
https://eprints.whiterose.ac.uk/162755/1/e202000735.full.pdf
https://eprints.whiterose.ac.uk/162755/1/e202000735.full.pdf
Autor:
A. Couturier, Stylianos E. Antonarakis, Claudine Rey-Berthod, Pierre Hutter, Ariane Paoloni-Giacobino
Publikováno v:
Human Genetics, Vol. 111, No 3 (2002) pp. 284-289
DNA sequences of mono-, di-, and trinucleotide repeats are prone to replication errors and thus constitute mutational hot spots. This is well illustrated by the occurrence of DNA microsatellite instability in tumors from patients affected by heredita
Autor:
Marc Prentki, Marc Y. Donath, Thierry Berney, Fabienne T. Schulthess, Christelle Bielman, Christophe Bonny, Kathrin Maedler, Raphaël Roduit
Publikováno v:
FASEB Journal, Vol. 22, No 6 (2008) pp. 1905-1913
c-Jun N-terminal kinases (SAPK/JNKs) are activated by inflammatory cytokines, and JNK signaling is involved in insulin resistance and beta-cell secretory function and survival. Chronic high glucose concentrations and leptin induce interleukin-1beta (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1dbf2a23b2b4d12421245af097f74f
Autor:
Paul Heuschling, Sophie Losciuto, Catherine Dostert, Mélanie Kirchmeyer, Audrey Gustin, Eric Koncina, Tony Heurtaux, Aubry Tardivel, Paul Felten
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130624 (2015)
PLoS ONE, 10(6). San Franscisco, CA: Public Library of Science (2015).
PLoS ONE
Plos One, vol. 10, no. 6, pp. e0130624
PLoS ONE, 10(6). San Franscisco, CA: Public Library of Science (2015).
PLoS ONE
Plos One, vol. 10, no. 6, pp. e0130624
Neuroinflammation is the local reaction of the brain to infection, trauma, toxic molecules or protein aggregates. The brain resident macrophages, microglia, are able to trigger an appropriate response involving secretion of cytokines and chemokines,