Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Casillas LN"'
Autor:
Mahajan MK; Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, PA, USA. Electronic address: mukesh.k.mahajan@gsk.com., Rivera EJ; Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, PA, USA., Sun HH; Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, PA, USA., Nagilla R; Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, PA, USA., DeMartino MP; Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, PA, USA., Haile PA; Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, PA, USA., Casillas LN; Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, PA, USA., Marquis RW; Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, PA, USA., Votta BJ; Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, PA, USA., Bertin J; Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, PA, USA., Reilly MA; Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Collegeville, PA, USA.
Publikováno v:
Journal of pharmaceutical sciences [J Pharm Sci] 2020 Oct; Vol. 109 (10), pp. 3160-3171. Date of Electronic Publication: 2020 Jun 18.
Autor:
Haile PA, Casillas LN, Bury MJ, Mehlmann JF, Singhaus R Jr, Charnley AK, Hughes TV, DeMartino MP, Wang GZ, Romano JJ, Dong X, Plotnikov NV, Lakdawala AS, Duraiswami C, Convery MA, Votta BJ, Lipshutz DB, Desai BM, Swift B, Capriotti CA, Berger SB, Mahajan MK, Reilly MA, Rivera EJ, Sun HH, Nagilla R, LePage C, Ouellette MT, Totoritis RD, Donovan BT, Brown BS, Chaudhary KW, Gough PJ, Bertin J, Marquis RW
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2020 Jun 02; Vol. 11 (6), pp. 1353. Date of Electronic Publication: 2020 Jun 02 (Print Publication: 2020).
Autor:
Haile PA; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Casillas LN; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Votta BJ; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Wang GZ; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Charnley AK; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Dong X; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Bury MJ; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Romano JJ; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Mehlmann JF; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., King BW; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Erhard KF; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Hanning CR; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Lipshutz DB; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Desai BM; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Capriotti CA; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Schaeffer MC; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Berger SB; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Mahajan MK; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Reilly MA; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Nagilla R; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Rivera EJ; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Sun HH; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Kenna JK; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Beal AM; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Ouellette MT; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Kelly M; GlaxoSmithKline , Gunnels Wood Road , Stevenage , Hertfordshire SG1 2NY , U.K., Stemp G; GlaxoSmithKline , Gunnels Wood Road , Stevenage , Hertfordshire SG1 2NY , U.K., Convery MA; GlaxoSmithKline , Gunnels Wood Road , Stevenage , Hertfordshire SG1 2NY , U.K., Vossenkämper A; Centre for Immunobiology, Blizard Institute, Barts and The London School of Medicine and Dentistry , Queen Mary University of London , London E1 2AD , U.K., MacDonald TT; Centre for Immunobiology, Blizard Institute, Barts and The London School of Medicine and Dentistry , Queen Mary University of London , London E1 2AD , U.K., Gough PJ; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Bertin J; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States., Marquis RW; GlaxoSmithKline , Collegeville Road , Collegeville , Pennsylvania 19426 , United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2019 Jul 25; Vol. 62 (14), pp. 6482-6494. Date of Electronic Publication: 2019 Jul 02.
Autor:
Haile PA; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Casillas LN; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Bury MJ; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Mehlmann JF; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Singhaus R Jr; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Charnley AK; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Hughes TV; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., DeMartino MP; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Wang GZ; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Romano JJ; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Dong X; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Plotnikov NV; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Lakdawala AS; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Convery MA; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom., Votta BJ; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Lipshutz DB; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Desai BM; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Swift B; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Capriotti CA; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Berger SB; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Mahajan MK; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Reilly MA; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Rivera EJ; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Sun HH; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Nagilla R; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., LePage C; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Ouellette MT; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Totoritis RD; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Donovan BT; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Brown BS; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Chaudhary KW; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Gough PJ; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Bertin J; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States., Marquis RW; GlaxoSmithKline, Collegeville Road, Collegeville, Pennsylvania 19426, United States.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2018 Sep 26; Vol. 9 (10), pp. 1039-1044. Date of Electronic Publication: 2018 Sep 26 (Print Publication: 2018).
Autor:
Haile PA, Votta BJ, Marquis RW, Bury MJ, Mehlmann JF, Singhaus R Jr, Charnley AK, Lakdawala AS, Convery MA; Platform Technology and Science, GlaxoSmithKline, Medicines Research Centre , Stevenage, SG1 2NY, UK., Lipshutz DB, Desai BM, Swift B, Capriotti CA, Berger SB, Mahajan MK, Reilly MA, Rivera EJ, Sun HH, Nagilla R, Beal AM, Finger JN, Cook MN, King BW, Ouellette MT, Totoritis RD, Pierdomenico M; Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA) , 00196 Rome, Italy., Negroni A; Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA) , 00196 Rome, Italy., Stronati L; Department of Cellular Biotechnology and Hematology, Sapienza University Hospital Umberto I , 00161 Rome, Italy., Cucchiara S; Department of Pediatrics, Pediatric Gastroenterology and Liver Unit, Sapienza University Hospital Umberto I , 00161 Rome, Italy., Ziółkowski B; Endoscopy Unit, Barts Health, Royal London Hospital , E1 1BB London, U.K., Vossenkämper A; Centre for Immunobiology, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London , E1 2AD London, U.K., MacDonald TT; Centre for Immunobiology, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London , E1 2AD London, U.K., Gough PJ, Bertin J, Casillas LN
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2016 May 26; Vol. 59 (10), pp. 4867-80. Date of Electronic Publication: 2016 May 04.
Autor:
Bondeson DP; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA., Mares A; GSK Medicines Research Centre, Stevenage, UK., Smith IE; GSK Medicines Research Centre, Stevenage, UK., Ko E; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA., Campos S; GSK Medicines Research Centre, Stevenage, UK., Miah AH; GSK Medicines Research Centre, Stevenage, UK., Mulholland KE; GSK Medicines Research Centre, Stevenage, UK., Routly N; GSK Medicines Research Centre, Stevenage, UK., Buckley DL; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA., Gustafson JL; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA., Zinn N; Cellzome, a GSK company, Heidelberg, Germany., Grandi P; Cellzome, a GSK company, Heidelberg, Germany., Shimamura S; Cellzome, a GSK company, Heidelberg, Germany., Bergamini G; Cellzome, a GSK company, Heidelberg, Germany., Faelth-Savitski M; Cellzome, a GSK company, Heidelberg, Germany., Bantscheff M; Cellzome, a GSK company, Heidelberg, Germany., Cox C; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA., Gordon DA; Arvinas, Inc., New Haven, Connecticut, USA., Willard RR; Arvinas, Inc., New Haven, Connecticut, USA., Flanagan JJ; Arvinas, Inc., New Haven, Connecticut, USA., Casillas LN; Pattern Recognition Receptor Discovery Performance Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA., Votta BJ; Pattern Recognition Receptor Discovery Performance Unit, GlaxoSmithKline, Collegeville, Pennsylvania, USA., den Besten W; Division of Biology &Biological Engineering, California Institute of Technology, Pasadena, California, USA., Famm K; GSK Medicines Research Centre, Stevenage, UK., Kruidenier L; GSK Medicines Research Centre, Stevenage, UK., Carter PS; GSK Medicines Research Centre, Stevenage, UK., Harling JD; GSK Medicines Research Centre, Stevenage, UK., Churcher I; GSK Medicines Research Centre, Stevenage, UK., Crews CM; 1] Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA. [2] Department of Chemistry, Yale University, New Haven, Connecticut, USA. [3] Department of Pharmacology, Yale University, New Haven, Connecticut, USA.
Publikováno v:
Nature chemical biology [Nat Chem Biol] 2015 Aug; Vol. 11 (8), pp. 611-7. Date of Electronic Publication: 2015 Jun 10.
Autor:
Mandal P; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA., Berger SB; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA., Pillay S; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA., Moriwaki K; Department of Pathology, Immunology and Microbiology Program, University of Massachusetts Medical School, Worcester, MA 01605, USA., Huang C; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA., Guo H; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA., Lich JD; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA., Finger J; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA., Kasparcova V; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA., Votta B; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA., Ouellette M; Molecular Discovery Research, Platform Technologies and Science, GlaxoSmithKline, Collegeville, PA 19426, USA., King BW; Molecular Discovery Research, Platform Technologies and Science, GlaxoSmithKline, Collegeville, PA 19426, USA., Wisnoski D; Molecular Discovery Research, Platform Technologies and Science, GlaxoSmithKline, Collegeville, PA 19426, USA., Lakdawala AS; Molecular Discovery Research, Platform Technologies and Science, GlaxoSmithKline, Collegeville, PA 19426, USA., DeMartino MP; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA., Casillas LN; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA., Haile PA; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA., Sehon CA; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA., Marquis RW; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA., Upton J; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA., Daley-Bauer LP; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA., Roback L; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA., Ramia N; Department of Pathology, Immunology and Microbiology Program, University of Massachusetts Medical School, Worcester, MA 01605, USA., Dovey CM; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA., Carette JE; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA., Chan FK; Department of Pathology, Immunology and Microbiology Program, University of Massachusetts Medical School, Worcester, MA 01605, USA., Bertin J; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA., Gough PJ; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA., Mocarski ES; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address: mocarski@emory.edu., Kaiser WJ; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address: wkaiser@emory.edu.
Publikováno v:
Molecular cell [Mol Cell] 2014 Nov 20; Vol. 56 (4), pp. 481-95. Date of Electronic Publication: 2014 Nov 20.
Autor:
Irving AT; Centre for Cancer Research, Monash Institute of Medical Research, Clayton, VIC 3168, Australia., Mimuro H; Division of Bacteriology, Department of Infectious Diseases Control, International Research Center for Infectious Diseases, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan., Kufer TA; Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Köln 50931, Germany., Lo C; Monash Micro Imaging, Clayton, VIC 3168, Australia., Wheeler R; Institut Pasteur, Unité Biologie et Génétique de la Paroi Bactérienne, Paris 75015, France; INSERM, Avenir group, Paris 75015, France., Turner LJ; Centre for Innate Immunity and Infectious Diseases, Monash Institute of Medical Research, Clayton, VIC 3168, Australia., Thomas BJ; Centre for Innate Immunity and Infectious Diseases, Monash Institute of Medical Research, Clayton, VIC 3168, Australia; Monash Lung and Sleep, Monash Medical Centre, Clayton, VIC 3168, Australia., Malosse C; Institut Pasteur, Structural Mass Spectrometry and Proteomics Unit, Paris 75015, France., Gantier MP; Centre for Cancer Research, Monash Institute of Medical Research, Clayton, VIC 3168, Australia., Casillas LN; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapy Area, GlaxoSmithKline, Collegeville, PA 19426-0989, USA., Votta BJ; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapy Area, GlaxoSmithKline, Collegeville, PA 19426-0989, USA., Bertin J; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapy Area, GlaxoSmithKline, Collegeville, PA 19426-0989, USA., Boneca IG; Institut Pasteur, Unité Biologie et Génétique de la Paroi Bactérienne, Paris 75015, France; INSERM, Avenir group, Paris 75015, France., Sasakawa C; Division of Bacterial Infection Biology, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan; Nippon Institute for Biological Science, Tokyo 198-0024, Japan; Medical Mycology Research Center, Chiba University, Chiba 260-8673, Japan., Philpott DJ; Department of Immunology, University of Toronto, Toronto, ON M5S 1A8, Canada., Ferrero RL; Centre for Innate Immunity and Infectious Diseases, Monash Institute of Medical Research, Clayton, VIC 3168, Australia., Kaparakis-Liaskos M; Centre for Innate Immunity and Infectious Diseases, Monash Institute of Medical Research, Clayton, VIC 3168, Australia. Electronic address: maria.liaskos@monash.edu.
Publikováno v:
Cell host & microbe [Cell Host Microbe] 2014 May 14; Vol. 15 (5), pp. 623-35. Date of Electronic Publication: 2014 Apr 17.
Autor:
Thorneloe KS; Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapy Area Unit, GlaxoSmithKline, 709 Swedeland Road, King of Prussia, PA 19406, USA. Kevin.S.Thorneloe@gsk.com, Cheung M, Bao W, Alsaid H, Lenhard S, Jian MY, Costell M, Maniscalco-Hauk K, Krawiec JA, Olzinski A, Gordon E, Lozinskaya I, Elefante L, Qin P, Matasic DS, James C, Tunstead J, Donovan B, Kallal L, Waszkiewicz A, Vaidya K, Davenport EA, Larkin J, Burgert M, Casillas LN, Marquis RW, Ye G, Eidam HS, Goodman KB, Toomey JR, Roethke TJ, Jucker BM, Schnackenberg CG, Townsley MI, Lepore JJ, Willette RN
Publikováno v:
Science translational medicine [Sci Transl Med] 2012 Nov 07; Vol. 4 (159), pp. 159ra148.
Autor:
Thorneloe KS; Cardiovascular and Urogenital Centre of Excellence in Drug Discovery, GlaxoSmithKline Pharmaceuticals, 709 Swedeland Road, King of Prussia, PA 19406, USA. Kevin.S.Thorneloe@gsk.com, Sulpizio AC, Lin Z, Figueroa DJ, Clouse AK, McCafferty GP, Chendrimada TP, Lashinger ES, Gordon E, Evans L, Misajet BA, Demarini DJ, Nation JH, Casillas LN, Marquis RW, Votta BJ, Sheardown SA, Xu X, Brooks DP, Laping NJ, Westfall TD
Publikováno v:
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2008 Aug; Vol. 326 (2), pp. 432-42. Date of Electronic Publication: 2008 May 22.