Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Casey Y. Carmichael"'
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
We have previously reported that brain Gαi2 subunit proteins are required to maintain sodium homeostasis and are endogenously upregulated in the hypothalamic paraventricular nucleus (PVN) in response to increased dietary salt intake to maintain a sa
Externí odkaz:
https://doaj.org/article/4c02f0509f544d89a07ab29ca54daea1
Autor:
Sarah Mahne, Jonathan S. Williams, Crissey L. Pascale, Daniel R. Kapusta, Richard D Wainford, Casey Y. Carmichael, Douglas L. Rosene, Jill T. Kuwabara, J. Thomas Cunningham, Jesse D. Moreira
Publikováno v:
Hypertension. 75:1002-1011
We have previously reported that in salt-resistant rat phenotypes brain, Gαi 2 (guanine nucleotide–binding protein alpha inhibiting activity polypeptide 2) proteins are required to maintain blood pressure and sodium balance. However, the impact of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a62913321ed4c1114b0ba410ea46ad9
https://doi.org/10.1161/hypertensionaha.119.13777
https://doi.org/10.1161/hypertensionaha.119.13777
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology, Vol 12 (2021)
We have previously reported that brain Gαi2 subunit proteins are required to maintain sodium homeostasis and are endogenously upregulated in the hypothalamic paraventricular nucleus (PVN) in response to increased dietary salt intake to maintain a sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287faf6b3c9ba6ac42aa061b0c7f0f83
Autor:
Richard D Wainford, Alissa A. Frame, Jill T. Kuwabara, J. Thomas Cunningham, Casey Y. Carmichael
Publikováno v:
Experimental Physiology
NEW FINDINGS What is the central question of this study? What are the differential roles of the mechanosensitive and chemosensitive afferent renal nerves in the reno-renal reflex that promotes natriuresis, sympathoinhibition and normotension during a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02c0b459f692783280ed2cfe8a25105
http://europepmc.org/articles/PMC6675646
http://europepmc.org/articles/PMC6675646
Autor:
Casey Y, Carmichael, Jill T, Kuwabara, Crissey L, Pascale, Jesse D, Moreira, Sarah E, Mahne, Daniel R, Kapusta, Douglas L, Rosene, Jonathan S, Williams, J Thomas, Cunningham, Richard D, Wainford
Publikováno v:
Hypertension
We have previously reported that in salt resistant rat phenotypes brain guanine nucleotide-binding protein alpha inhibiting activity polypeptide 2 (Gαi(2)) proteins are required to maintain blood pressure and sodium balance. However, the impact of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92b44614f17ad860e9f0357af000df31
https://pubmed.ncbi.nlm.nih.gov/32148128
https://pubmed.ncbi.nlm.nih.gov/32148128
Autor:
Casey Y. Carmichael, Richard D Wainford, Alana C Carmichael, J. T. Cunningham, Jill T. Kuwabara
Publikováno v:
Acta Physiologica (Oxford, England)
Aim We determined the role of brain Gαi2 proteins in mediating the neural and humoral responses of conscious male Sprague–Dawley rats to acute peripheral sodium challenge. Methods Rats pre-treated (24-h) intracerebroventricularly with a targeted o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98e47fea0762f745c390ec946c99a3f
https://doi.org/10.1111/apha.12610
https://doi.org/10.1111/apha.12610
Publikováno v:
Hypertension. 65:178-186
Excess dietary salt intake is an established cause of hypertension. At present, our understanding of the neuropathophysiology of salt-sensitive hypertension is limited by a lack of identification of the central nervous system mechanisms that modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d93b19ea4cf44a63995971e125f3d9
https://doi.org/10.1161/hypertensionaha.114.04463
https://doi.org/10.1161/hypertensionaha.114.04463
Publikováno v:
Current Hypertension Reports
Purpose of Review The etiology of hypertension, a critical public health issue affecting one in three US adults, involves the integration of the actions of multiple organ systems, including the renal sympathetic nerves. The renal sympathetic nerves,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd978addf1e5f9005514b7b2862d914
https://pubmed.ncbi.nlm.nih.gov/27595156
https://pubmed.ncbi.nlm.nih.gov/27595156
Publikováno v:
Hypertension. 68
Aim: We hypothesize that challenges to sodium homeostasis differentially activate chemo- vs. mechanosensitive afferent renal nerves to evoke sympathoinhibition, sodium homeostasis and normotension in the Sprague-Dawley (SD) rat. Methods: Conscious SD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06aca70eb66510bacd056e944a722028
https://doi.org/10.1161/hyp.68.suppl_1.121
https://doi.org/10.1161/hyp.68.suppl_1.121
Autor:
Casey Y Carmichael, Richard D Wainford
Publikováno v:
Hypertension. 66
Aim: To determine the role of brain Gαi 2 proteins in mediating sodium-evoked PVN neuronal activation and blood pressure regulation in conscious rats. Methods: 24-h intracerebroventricular scrambled (SCR) or Gαi 2 oligodeoxynucleotide (ODN; 25μg/5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c321a8519cb82cb0bd4106dd9b402bb
https://doi.org/10.1161/hyp.66.suppl_1.035
https://doi.org/10.1161/hyp.66.suppl_1.035