Výsledky vyhledávání - "Casey S John"

Akademický článek

Dementia risk and dynamic response to exercise: A non-randomized clinical trial.

Autor: Eric D Vidoni, Jill K Morris, Jacqueline A Palmer, Yanming Li, Dreu White, Paul J Kueck, Casey S John, Robyn A Honea, Rebecca J Lepping, Phil Lee, Jonathan D Mahnken, Laura E Martin, Sandra A Billinger

Publikováno v: PLoS ONE, Vol 17, Iss 7, p e0265860 (2022)

BackgroundPhysical exercise may support brain health and cognition over the course of typical aging. The goal of this nonrandomized clinical trial was to examine the effect of an acute bout of aerobic exercise on brain blood flow and blood neurotroph

Externí odkaz: https://doaj.org/article/c9a2478f78d1461895a5e740aabd88bd

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Akademický článek

A methodology for an acute exercise clinical trial called dementia risk and dynamic response to exercise

Autor: Dreu White, Casey S. John, Ashley Kucera, Bryce Truver, Rebecca J. Lepping, Paul J. Kueck, Phil Lee, Laura Martin, Sandra A. Billinger, Jeffrey M. Burns, Jill K. Morris, Eric D. Vidoni

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

Abstract Exercise likely has numerous benefits for brain and cognition. However, those benefits and their causes remain imprecisely defined. If the brain does benefit from exercise it does so primarily through cumulative brief, “acute” exposures

Externí odkaz: https://doaj.org/article/088de346d53049a4b24ab5be9b41efc6

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Akademický článek

Relationship of fasting glucose and longitudinal Alzheimer's disease imaging markers

Autor: Robyn A. Honea, Casey S. John, Zachary D. Green, Paul J. Kueck, Matthew K. Taylor, Rebecca J. Lepping, Ryan Townley, Eric D. Vidoni, Jeffery M. Burns, Jill K. Morris

Publikováno v: Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)

Abstract Introduction Fasting glucose increases with age and is linked to modifiable Alzheimer's disease risk factors such as cardiovascular disease and Type 2 diabetes (T2D). Methods We leveraged available biospecimens and neuroimaging measures coll

Externí odkaz: https://doaj.org/article/837417a03d1c498db258d6d94f005cde

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Relationship of Muscle Apolipoprotein E Expression with Markers of Cellular Stress, Metabolism, and Blood Biomarkers in Cognitively Healthy and Impaired Older Adults

Autor: Chelsea N. Johnson, Colin S. McCoin, Paul J. Kueck, Amelia G. Hawley, Casey S. John, John P. Thyfault, Russell H. Swerdlow, Paige C. Geiger, Jill K. Morris

Publikováno v: Journal of Alzheimer's Disease. 92:1027-1035

Background: Individuals with mild cognitive impairment (MCI) have reduced lipid-stimulated mitochondrial respiration in skeletal muscle. A major risk factor for Alzheimer’s disease (AD), the apolipoprotein E4 (APOE4) allele, is implicated in lipid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cfd268a6880b9007d043552554a6b741
https://doi.org/10.3233/jad-221192

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Akademický článek

Characterization of the Meal-Stimulated Incretin Response and Relationship With Structural Brain Outcomes in Aging and Alzheimer’s Disease

Autor: Jill K. Morris, Casey S. John, Zachary D. Green, Heather M. Wilkins, Xiaowan Wang, Ashwini Kamat, Russell S. Swerdlow, Eric D. Vidoni, Melissa E. Petersen, Sid E. O’Bryant, Robyn A. Honea, Jeffrey M. Burns

Publikováno v: Frontiers in Neuroscience, Vol 14 (2020)

BackgroundIndividuals with Alzheimer’s Disease (AD) are often characterized by systemic markers of insulin resistance; however, the broader effects of AD on other relevant metabolic hormones, such as incretins that affect insulin secretion and food

Externí odkaz: https://doaj.org/article/7b81b1d0d73a48599fdddca440078ca0

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Akademický článek

Collective effects of age, sex, genotype, and cognitive status on fitness outcomes

Autor: Jill K. Morris, Guanlin Zhang, Ryan J Dougherty, Jonathan D. Mahnken, Casey S. John, Sarah R. Lose, Dane B. Cook, Jeffrey M. Burns, Eric D. Vidoni, Ozioma Okonkwo

Publikováno v: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)

Abstract Introduction Individuals with Alzheimer's disease (AD) broadly exhibit lower cardiorespiratory fitness (CRF) compared to cognitively healthy older adults. Other factors, such as increasing age and female sex, are also known to track with low

Externí odkaz: https://doaj.org/article/f00dfb6220184acf83f9c6ccecd718fc

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