Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Casey Pence"'
Autor:
Casey Pence, Majed Matar, David Ulkoski, Leslie Wilkinson, Jason G. Fewell, Elaine Brunhoeber, Kirby Wallace, Diane McClure, Gregory Slobodkin, Jennifer Rice, Richard Congo, Angela Rea-Ramsey, Kevin Polach, Jeff Sparks, Khursheed Anwer
Publikováno v:
Journal of Controlled Release. 158:269-276
Exploitation of the RNA interference (RNAi) pathway offers the promise of new and effective therapies for a wide variety of diseases. Clinical development of new drugs based on this platform technology is still limited, however, by a lack of safe and
Autor:
Danny H. Lewis, Jason G. Fewell, Khursheed Anwer, Miranda Worker, Gregory Slobodkin, Casey Pence, Majed Matar, Elaine Brunhoeber, Jennifer Rice
Publikováno v:
The journal of gene medicine. 11(8)
Background The poor prognosis associated with ovarian cancer is primarily the result of delayed diagnosis and the lack of an effective treatment for advanced disease. Use of novel immunotherapy strategies are being evaluated that work to enhance loca
Autor:
Kevin Polach, Casey Pence, Khursheed Anwer, Angela Rea-Ramsey, Jennifer Rice, Jason G. Fewell, Elaine Brunhoeber, Diane McClure, Majed Matar, Leslie Wilkinson, Jeff Sparks
Publikováno v:
Cancer Research. 72:B17-B17
Exploiting the RNAi pathway offers the potential to advance the treatment of many diseases through highly specific and efficient silencing of gene products. Unfortunately, the requisite safe and efficient delivery of nucleic acids to target cells rem
Autor:
Elaine Brunhoeber, Richard Congo, Gregory Slobodkin, Jennifer Rice, Angela Rea-Ramsey, Khursheed Anwer, Jason G. Fewell, Jeff Sparks, Kevin Polach, Casey Pence, Majed Matar, Diane McClure, Leslie Wilkinson
Publikováno v:
Cancer Research. 71:4995-4995
RNA interference offers the promise of a new class of therapeutics that can specifically target many diseases that have aberrant gene expression as the root cause. This is potentially true even for diseases that are currently considered non-druggable
Autor:
Jason G. Fewell, Diane McClure, Jeff Sparks, Majed Matar, Angela Rea-Ramsey, Elaine Brunhoeber, Jennifer Rice, Gregory Slobodkin, Richard Congo, Khursheed Anwer, Casey Pence, Kevin Polach, Leslie Wilkinson
Publikováno v:
Cancer Research. 70:5535-5535
The efficient delivery of siRNA molecules to target cells is critical for the application of RNAi to the treatment of human cancers. To this end, we have developed novel cationic lipopolyamime structures that can be used to complex or encapsulate siR