Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Casey P. Robinson"'
Publikováno v:
European Journal of Pharmacology. 359:191-200
The modulating role of estrogens and ovariectomy on coronary artery and thoracic aortic rings was examined in female rabbits. Three treatment groups were studied: (1) control, (2) ovariectomy, and (3) ovariectomy + 17beta-estradiol acetate (40 microg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b4a87220ce0ea4659df8f319c06086
https://doi.org/10.1016/s0014-2999(98)00644-x
https://doi.org/10.1016/s0014-2999(98)00644-x
Publikováno v:
Toxicology and Applied Pharmacology. 138:72-76
Ricin, at toxic glycoprotein from the castor bean, causes myocardial hemorrhage and a decrease in blood pressure. We studied the effects of ricin on myocardial function in the isolated rabbit heart. Rabbits were given 0.22 micrograms/kg of ricin i.v.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0ad37b1a7b56d20583e1fdf0e4df61
https://doi.org/10.1006/taap.1996.0099
https://doi.org/10.1006/taap.1996.0099
Publikováno v:
Toxicology and Applied Pharmacology. 129:16-22
We have previously shown that ricin, a toxic lectin from the castor bean, increases cardiac output and blood flow to the heart in rabbits in the early stage of its intoxication and causes hemorrhage and necrosis in the heart following a lethal dose.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992b30577c7a14a42f26c9d19dd33855
https://doi.org/10.1006/taap.1994.1224
https://doi.org/10.1006/taap.1994.1224
Publikováno v:
Journal of Biochemical Toxicology. 9:219-223
Ricin is a toxic lectin that inhibits protein synthesis. Because ricin decreases arterial pressure and causes cardiovascular collapse, its effects on the vascular neuroeffector system were investigated. Rabbits were given either of two doses of ricin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8155d3016836eb853d4a8abc4f095d33
https://doi.org/10.1002/jbt.2570090407
https://doi.org/10.1002/jbt.2570090407
Publikováno v:
Pharmacology & Toxicology. 74:148-152
Ricin is a toxic lectin from the castor bean. The time course of its toxic effects on the cardiovascular system of rabbits was investigated after determining its LD50 and minimum lethal dose in rabbits by the Up and Down method, as a basis for dosing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3de6231e5a67693081dbcfde84b81dd
https://doi.org/10.1111/j.1600-0773.1994.tb01090.x
https://doi.org/10.1111/j.1600-0773.1994.tb01090.x
Publikováno v:
Life Sciences. 54:1465-1469
Terbutaline is a widely used, selective β 2 -adrenergic agonist whose penetration into brain has not been demonstrated in laboratory animals. Although its tissue uptake has been reported in some animals, no uptake into brain has been demonstrated. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3795eae57e4a014e91617cefeee10069
https://doi.org/10.1016/0024-3205(94)90013-2
https://doi.org/10.1016/0024-3205(94)90013-2
Publikováno v:
Toxicon. 29:1009-1017
The contractile effects of the tumor promoter and protein kinase C activator, lyngbyatoxin A, were studied in rabbit aorta rings. Contractions to 1 microM lyngbyatoxin A developed slowly, becoming maximal in approximately 3 hr. Contractions were not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054b2f13ba40eb4b7ad2e550efb81de2
https://doi.org/10.1016/0041-0101(91)90083-4
https://doi.org/10.1016/0041-0101(91)90083-4
Autor:
Casey P. Robinson, David R. Franz
Publikováno v:
Pharmaceutical Research. :859-864
The effects of palytoxin (PTX) on airway smooth muscle were investigated in opened rings of guinea pig trachea. Concentrations of PTX from 10 pM to 100 nM caused contractions of tracheal strips, with maximal contractions approximately 80% of those in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64fe04e03d79e6f1993bf81b71db50ed
https://doi.org/10.1023/a:1015895227196
https://doi.org/10.1023/a:1015895227196
Publikováno v:
Toxicology Letters. 54:33-37
The acute addition of 10 microM soman to rabbit aorta rings did not increase resting 45Ca2+ influx significantly in the absence or presence of 10 microM norepinephrine or 80 mM potassium (P greater than 0.05). However, agonist-induced 45Ca2+ influx i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c50851318b4cfa288ae832a00e11af4e
https://doi.org/10.1016/0378-4274(90)90052-n
https://doi.org/10.1016/0378-4274(90)90052-n
Autor:
Casey P. Robinson, Chao Yu Hu
Publikováno v:
Bulletin of Environmental Contamination and Toxicology. 44:590-594
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570a42abd3b5cfcdbfba70e3b40039dd
https://doi.org/10.1007/bf01700881
https://doi.org/10.1007/bf01700881