Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Casey P. Collins"'
Autor:
Casey P. Collins, John F. McCarthy
Publikováno v:
Journal of Regional Medical Campuses, Vol 1, Iss 1 (2018)
Purpose To investigate whether education at a regional medical campus (RMC) affects the likelihood of University of Washington School of Medicine (UWSOM) students choosing a primary care specialty. Method Two approaches were taken to answer
Externí odkaz:
https://doaj.org/article/a5e4574e2f514055a1814e2bc5d0b7a3
Autor:
Casey R. Collins
Publikováno v:
Journal of Global Buddhism, Vol 21 (2020)
Externí odkaz:
https://doaj.org/article/12f75aff067f4a41b2c5e9867a0deae4
Publikováno v:
Molecular Carcinogenesis. 55:1761-1771
Prostate cancer (PC) is the second leading cause of cancer related deaths in US men. Androgen deprivation therapy (ADT) improves clinical outcome, but tumors often recur and progress to androgen independent prostate cancer (AIPC) which no longer resp
Autor:
Jonah D. Hocum, David J. Leap, Diana L. Browning, Casey P. Collins, Dustin T. Rae, Grant D. Trobridge
Publikováno v:
Human gene therapy. 27(3)
Retroviral vector-mediated gene therapy is promising, but genotoxicity has limited its use in the clinic. Genotoxicity is highly dependent on the retroviral vector used, and foamy viral (FV) vectors appear relatively safe. However, internal promoters
Autor:
Ian Linde, Casey P. Collins, Grant D. Trobridge, Lindsay K. Matern, Dustin T. Rae, Jonah D. Hocum
Publikováno v:
Scientific Reports
Retroviral gene therapy offers immense potential to treat many genetic diseases and has already shown efficacy in clinical trials. However, retroviral vector mediated genotoxicity remains a major challenge and clinically relevant approaches to reduce
High-throughput mapping of retroviral vector integration sites (RIS) has become an invaluable tool to evaluate novel gene therapy vectors and to track clonal contribution in preclinical and clinical studies. Beard et al. (Methods Mol Biol 2014;1185:3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798d1dd96d981d3c9b97ed8089761b79
https://europepmc.org/articles/PMC4677540/
https://europepmc.org/articles/PMC4677540/
Autor:
Grant D. Trobridge, Casey P. Collins, Ian Linde, Dustin T. Rae, Jonah D. Hocum, Lindsay K. Matern
Publikováno v:
Molecular Therapy. 23
Retroviral (RV) vector mediated gene therapy offers immense potential for permanently treating a broad spectrum of genetic conditions and has shown efficacy in clinical trials. However, vector proviruses can dysregulate nearby host genes, referred to
Autor:
Jonah D. Hocum, Grant D. Trobridge, Lindsay K. Matern, Ian Linde, Casey P. Collins, Dustin T. Rae
Publikováno v:
Molecular Therapy. 24:S3-S4
Hematopoietic stem cell gene therapy offers immense potential to treat many genetic diseases and has already shown efficacy in clinical trials. However, retroviral vector mediated gene dysregulation, known as genotoxicity, remains a major challenge a