Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Casey Lansdell"'
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) are a promising cell-free therapy for acute lung injury (ALI). To date, no studies have investigated their biodistribution in ALI or discerned the timing of adminis
Externí odkaz:
https://doaj.org/article/167e6d7cf2a64263b653474a28528649
Autor:
Victoria T Hunniford, Agnes Grudniewicz, Dean A Fergusson, Joshua Montroy, Emma Grigor, Casey Lansdell, Manoj M Lalu, On behalf of The Canadian Critical Care Translational Biology Group
Publikováno v:
eLife, Vol 12 (2023)
Background: Multicentric approaches are widely used in clinical trials to assess the generalizability of findings, however, they are novel in laboratory-based experimentation. It is unclear how multilaboratory studies may differ in conduct and result
Externí odkaz:
https://doaj.org/article/c3bacf29ec004c61ba79555030c592f1
Autor:
Annabelle Pfeifle, Sathya N. Thulasi Raman, Casey Lansdell, Wanyue Zhang, Levi Tamming, Jonathon Cecillon, Emmanuel Laryea, Devina Patel, Jianguo Wu, Caroline Gravel, Grant Frahm, Jun Gao, Wangxue Chen, George Chaconas, Simon Sauve, Michael Rosu-Myles, Lisheng Wang, Michael J. W. Johnston, Xuguang Li
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe incidence of Lyme disease (LD) in Canada and the United States has risen over the last decade, nearing 480,000 cases each year. Borrelia burgdorferi sensu lato, the causative agent of LD, is transmitted to humans through the bite of a
Externí odkaz:
https://doaj.org/article/f0e5aaec002d4d639fc98c48521fb471
Autor:
Wanyue Zhang, Annabelle Pfeifle, Casey Lansdell, Grant Frahm, Jonathon Cecillon, Levi Tamming, Caroline Gravel, Jun Gao, Sathya N. Thulasi Raman, Lisheng Wang, Simon Sauve, Michael Rosu-Myles, Xuguang Li, Michael J. W. Johnston
Publikováno v:
Vaccines, Vol 11, Iss 10, p 1580 (2023)
In recent years, lipid nanoparticles (LNPs) have emerged as a revolutionary technology for vaccine delivery. LNPs serve as an integral component of mRNA vaccines by protecting and transporting the mRNA payload into host cells. Despite their prominenc
Externí odkaz:
https://doaj.org/article/747e2768207344e39af4cad79c47ad35
Autor:
Asher A. Mendelson, Casey Lansdell, Alison E. Fox-Robichaud, Patricia Liaw, Jaskirat Arora, Jean-François Cailhier, Gediminas Cepinskas, Emmanuel Charbonney, Claudia dos Santos, Dhruva Dwivedi, Christopher G. Ellis, Dean Fergusson, Kirsten Fiest, Sean E. Gill, Kathryn Hendrick, Victoria T. Hunniford, Paulina M. Kowalewska, Karla Krewulak, Christian Lehmann, Kimberly Macala, John C. Marshall, Laura Mawdsley, Braedon McDonald, Ellen McDonald, Sarah K. Medeiros, Valdirene S. Muniz, Marcin Osuchowski, Justin Presseau, Neha Sharma, Sahar Sohrabipour, Janet Sunohara-Neilson, Gloria Vázquez-Grande, Ruud A. W. Veldhuizen, Donald Welsh, Brent W. Winston, Ryan Zarychanski, Haibo Zhang, Juan Zhou, Manoj M. Lalu, Sepsis Canada’s National Preclinical Sepsis Platform
Publikováno v:
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-19 (2021)
Abstract Despite decades of preclinical research, no experimentally derived therapies for sepsis have been successfully adopted into routine clinical practice. Factors that contribute to this crisis of translation include poor representation by precl
Externí odkaz:
https://doaj.org/article/9aeed005c2d54e4888a280f7bf96c4a3
Autor:
Sean E. Gill, Ellen McDonald, Christian Lehmann, Victoria T. Hunniford, Marcin F. Osuchowski, Karla D. Krewulak, Asher A. Mendelson, Janet Sunohara-Neilson, Manoj M. Lalu, Gloria Vazquez-Grande, Kathryn Hendrick, Christopher G. Ellis, John Marshall, Sarah K. Medeiros, Sahar Sohrabipour, Dean Fergusson, Dhruva J. Dwivedi, Neha Sharma, Haibo Zhang, Kirsten M. Fiest, Claudia C. dos Santos, Laura Mawdsley, Jaskirat Arora, Gediminas Cepinskas, Alison Fox-Robichaud, Jean-François Cailhier, Patricia C. Liaw, Ryan Zarychanski, Kimberly F. Macala, Brent W. Winston, Valdirene S Muniz, Ruud A. W. Veldhuizen, Justin Presseau, Emmanuel Charbonney, Casey Lansdell, Donald G. Welsh, Juan Zhou, Paulina M. Kowalewska, Braedon McDonald
Publikováno v:
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-19 (2021)
Intensive Care Medicine Experimental
Intensive Care Medicine Experimental
Despite decades of preclinical research, no experimentally derived therapies for sepsis have been successfully adopted into routine clinical practice. Factors that contribute to this crisis of translation include poor representation by preclinical mo
Autor:
Abhirami A Ananth, Lee-Hwa Tai, Casey Lansdell, Almohanad A Alkayyal, Katherine E Baxter, Leonard Angka, Jiqing Zhang, Christiano Tanese de Souza, Kyle B Stephenson, Kelley Parato, Jonathan L Bramson, John C Bell, Brian D Lichty, Rebecca C Auer
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159471 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0155947.].
Externí odkaz:
https://doaj.org/article/6726513060824e6e936b2c00406b88c8
Autor:
Abhirami A Ananth, Lee-Hwa Tai, Casey Lansdell, Almohanad A Alkayyal, Katherine E Baxter, Leonard Angka, Jiqing Zhang, Christiano Tanese de Souza, Kyle B Stephenson, Kelley Parato, Jonathan L Bramson, John C Bell, Brian D Lichty, Rebecca C Auer
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155947 (2016)
Anti-tumor CD8+ T cells are a key determinant for overall survival in patients following surgical resection for solid malignancies. Using a mouse model of cancer vaccination (adenovirus expressing melanoma tumor-associated antigen (TAA)-dopachrome ta
Externí odkaz:
https://doaj.org/article/551c7ca1f5e9471199f644eceec99f59
Autor:
Victoria Hunniford, Agnes Grudniewicz, Dean Ferguson, Joshua Ryan Montroy, Emma Grigor, Casey Lansdell, Manoj Mathew Lalu
Multicentric approaches are widely used in clinical trials to assess generalizability of findings, however they are novel in preclinical experimentation. We synthesized characteristics of multilaboratory studies and quantitatively compared them to si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e33fbaadf6737d14850234f9b7ab3e3
https://doi.org/10.31219/osf.io/92u7d
https://doi.org/10.31219/osf.io/92u7d