Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Casey L, Sayre"'
Autor:
Casey L. Sayre, Venkata Kashyap Yellepeddi, Kathleen M. Job, Lubov V. Krepkova, Catherine M. T. Sherwin, Elena Y. Enioutina
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Infants, children, and adolescents are at risk of experiencing a multitude of gastrointestinal disorders (GID). These disorders can adversely affect the quality of life or be life-threatening. Various interventions that span the conventional and comp
Externí odkaz:
https://doaj.org/article/b5e32992c75c4926a648978d0ee76dab
Autor:
Rachel E. Hudson, Kathleen M. Job, Casey L. Sayre, Lubov V. Krepkova, Catherine M. Sherwin, Elena Y. Enioutina
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Urinary tract infections (UTIs) are a significant clinical problem that pregnant women and children commonly experience. Escherichia coli is the primary causative organism, along with several other gram-negative and gram-positive bacteria. Antimicrob
Externí odkaz:
https://doaj.org/article/762d8dce6c1c4e928cc5ce9ed45e5e26
Publikováno v:
Research in Pharmaceutical Sciences, Vol 12, Iss 3, Pp 176-186 (2017)
Liquiritigenin is a chiral flavonoid present in licorice and other medicinal plants. The nature of its biological fate with respect to the individual enantiomers has not been examined. In this study, we characterize, for the first time, the stereosel
Externí odkaz:
https://doaj.org/article/f22579c79a70475f97fb685924cfb85e
Publikováno v:
Research in Pharmaceutical Sciences, Vol 11, Iss 5, Pp 355-365 (2016)
Liquiritigenin is a chiral flavonoid present in plant based food, nutraceuticals, and traditional medicines. It is also an important ingredient present in licorice. The purpose of this study is to explore the pharmacological activity of racemic liqui
Externí odkaz:
https://doaj.org/article/a77f13f7117949eb9372b2dc51093b0b
Autor:
Samaa Alrushaid, Neal M. Davies, Judy E. Anderson, Tyson Le, Jaime A. Yáñez, Zaid H. Maayah, Ayman O.S. El-Kadi, Ousama Rachid, Casey L. Sayre, Raimar Löbenberg, Frank J. Burczynski
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 21, Iss 1s (2018)
PURPOSE: MyoNovin is a novel skeletal muscle-regenerating compound developed through synthesis of two nitro groups onto a guaifenesin backbone to deliver nitric oxide to skeletal muscle with a potential to treat muscle atrophy. The purpose of this st
Externí odkaz:
https://doaj.org/article/e895d65cc6e748e6b35ead553dc5471e
Autor:
Ana Luísa de P. Oliveira, Stephanie E. Martinez, Kalyanam Nagabushnam, Muhammed Majeed, Samaa Alrushaid, Casey L. Sayre, Neal M. Davies
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 18, Iss 4 (2015)
Purpose: To develop a bioanalytical assay using RP-HPLC to quantify the curcuminoid calebin A, to characterize its pharmacokinetics in rats after intravenous (IV) and oral (PO) administration, to identify its pharmacological activities and to evaluat
Externí odkaz:
https://doaj.org/article/e276a135786a4fa396396801e8722346
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 18, Iss 4 (2015)
Purpose: Delineate the stereospecific pharmacokinetics and pharmacodynamics of the chiral flavonoids pinocembrin and pinostrobin. Objective: Characterize for the first time the stereoselective pharmacokinetics of two flavonoids, pinocembrin and pinos
Externí odkaz:
https://doaj.org/article/6b75ec7be93f488d97ad1cb4f9a2a8d3
Autor:
Júlia T. Novaes, Ryan Lillico, Casey L. Sayre, Kalyanam Nagabushanam, Muhammed Majeed, Yufei Chen, Emmanuel A. Ho, Ana Luísa de P. Oliveira, Stephanie E. Martinez, Samaa Alrushaid, Neal M. Davies, Ted M. Lakowski
Publikováno v:
Pharmaceutics, Vol 9, Iss 4, p 45 (2017)
Tetrahydrocurcumin (THC), curcumin and calebin-A are curcuminoids found in turmeric (Curcuma longa). Curcuminoids have been established to have a variety of pharmacological activities and are used as natural health supplements. The purpose of this st
Externí odkaz:
https://doaj.org/article/2b405f6be5b94c3493e7a516c715b867
Autor:
Samaa Alrushaid, Casey L. Sayre, Jaime A. Yáñez, M. Laird Forrest, Sanjeewa N. Senadheera, Frank J. Burczynski, Raimar Löbenberg, Neal M. Davies
Publikováno v:
Pharmaceutics, Vol 9, Iss 3, p 35 (2017)
Doxorubicin (Dox) is an effective anti-cancer medication with poor oral bioavailability and systemic toxicities. DoxQ was developed by conjugating Dox to the lymphatically absorbed antioxidant quercetin to improve Dox’s bioavailability and tolerabi
Externí odkaz:
https://doaj.org/article/3090fddc4f504d7c9d83bde50c24e222
Autor:
Anna Burrows, Marco Battaglia, John Strauss, Kevin K Watt, Casey L. Sayre, Venkata K. Yellepeddi, Simon J. C. Davies
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0232435 (2020)
PLoS ONE, Vol 15, Iss 7, p e0232435 (2020)
Anxiety disorders (AD) are the most common mental illnesses affecting an estimated 40 million adults in the United States. Amiloride, a diuretic agent, has shown efficacy in treating AD in preclinical models by inhibiting the acid-sensing ion channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a2b2ddb6d9af67a9f8d3530c8abd41
http://europepmc.org/articles/PMC7351165
http://europepmc.org/articles/PMC7351165