Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Casey Kohnhorst"'
Autor:
Erica J. Fratz-Berilla, Casey Kohnhorst, Nicholas Trunfio, Xin Bush, Aron Gyorgypal, Cyrus Agarabi
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e25512- (2024)
Culture pH is a critical process parameter during CHO cell bioreactor operations that is key for proper cell growth, protein production, and maintaining the critical quality attributes of a monoclonal antibody drug substance. The traditional means of
Externí odkaz:
https://doaj.org/article/acbdf2b755b546b48268b58abee6b86f
Autor:
Sai Rashmika Velugula-Yellela, Kurt Brorson, Cyrus Agarabi, David N. Powers, Talia Faison, Erica J. Fratz‐Berilla, Casey Kohnhorst
Publikováno v:
Biotechnology and Bioengineering
Mycoplasma contamination events in biomanufacturing facilities can result in loss of production and costly cleanups. Mycoplasma may survive in mammalian cell cultures with only subtle changes to the culture and may penetrate the 0.2 µm filters often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28fe4d4b1cb7397cfe00556fd2c793fd
http://europepmc.org/articles/PMC6900124
http://europepmc.org/articles/PMC6900124
Publikováno v:
Current Opinion in Chemical Engineering. 22:161-166
Adventitious agents are a safety risk to biomanufacturing pipelines, from cell line development to upstream and downstream processes. A contamination event can and has effectively shut down plant operations and resulted in drug shortages. To ensure t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0819d67d1c9aade37c2a6fd0919bd54e
https://doi.org/10.1016/j.coche.2018.09.012
https://doi.org/10.1016/j.coche.2018.09.012
Autor:
Sai Rashmika Velugula-Yellela, David N. Powers, Ryan J. Graham, Nicholas Trunfio, Erica J. Fratz‐Berilla, Adil Mohammad, Cyrus Agarabi, Talia Faison, Casey Kohnhorst, Phillip Angart
Publikováno v:
Biotechnology and Bioengineering
A mycoplasma contamination event in a biomanufacturing facility can result in costly cleanups and potential drug shortages. Mycoplasma may survive in mammalian cell cultures with only subtle changes to the culture and penetrate the standard 0.2‐µm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c901167f2fdf46a3630e46a690b4ffc6
https://pubmed.ncbi.nlm.nih.gov/32436993
https://pubmed.ncbi.nlm.nih.gov/32436993
Autor:
Cyrus Agarabi, Erica J. Fratz‐Berilla, David N. Powers, Talia Faison, Casey Kohnhorst, Phillip Angart, Sai Rashmika Velugula-Yellela, Anneliese Faustino
Publikováno v:
Journal of visualized experiments : JoVE. (147)
Monoclonal antibodies (mAbs) are one of the most popular and well-characterized biological products manufactured today. Most commonly produced using Chinese hamster ovary (CHO) cells, culture and process conditions must be optimized to maximize antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4046ef6f480abfe514027fc7e55894ba
https://pubmed.ncbi.nlm.nih.gov/31107445
https://pubmed.ncbi.nlm.nih.gov/31107445
Autor:
David N. Powers, Nicholas Trunfio, Sai Rashmika Velugula-Yellela, Anneliese Faustino, Erica Berilla, Talia Faison, Casey Kohnhorst, Phillip Angart, Cyrus Agarabi
Publikováno v:
Journal of Visualized Experiments : JoVE
Automated microscale bioreactors (15 mL) can be a useful tool for cell culture engineers. They facilitate the simultaneous execution of a wide variety of experimental conditions while minimizing potential process variability. Applications of this app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5bbdb4009aa8d33a4afbdf77b4b98e
https://doi.org/10.3791/58231
https://doi.org/10.3791/58231