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pro vyhledávání: '"Casey K Hua"'
Autor:
Casey K Hua, Albert T Gacerez, Charles L Sentman, Margaret E Ackerman, Yoonjoo Choi, Chris Bailey-Kellogg
Publikováno v:
eLife, Vol 6 (2017)
Understanding where antibodies recognize antigens can help define mechanisms of action and provide insights into progression of immune responses. We investigate the extent to which information about binding specificity implicitly encoded in amino aci
Externí odkaz:
https://doaj.org/article/98084b2d730f4ca092d680bf494a1c61
Autor:
Casey K. Hua, Margaret E. Ackerman
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Preclinical and early human clinical studies of broadly neutralizing antibodies (bNAbs) to prevent and treat HIV infection support the clinical utility and potential of bNAbs for prevention, postexposure prophylaxis, and treatment of acute and chroni
Externí odkaz:
https://doaj.org/article/e3d4ae883bbe43d99429b7a67a9730e5
Publikováno v:
Cancer Immunology, Immunotherapy. 67:749-759
B7H6 is emerging as a promising tumor antigen that is known to be expressed on a wide array of tumors and is reported to stimulate anti-tumor responses from the immune system. As such, B7H6 presents a good target for tumor-specific immunotherapies. B
Publikováno v:
Protein Engineering, Design and Selection. 30:713-721
As a stress-inducible natural killer (NK) cell ligand, B7H6 plays a role in innate tumor immunosurveillance and is a fairly tumor selective marker expressed on a variety of solid and hematologic cancer cells. Here, we describe the isolation and chara
Autor:
Casey K Huang, Anjani Weerasekara, Ji Lu, Robyn Carter, Karen D. Weynberg, Rachel Thomson, Scott Bell, Jianhua Guo
Publikováno v:
Water Research X, Vol 21, Iss , Pp 100201- (2023)
The regrowth and subsequent exposure of opportunistic pathogens (OPs) whilst reopening buildings that have been locked down due to the stay-at-home restrictions to limit the spread of COVID-19, is a public health concern. To better understand such mi
Externí odkaz:
https://doaj.org/article/1c33f04ddc4142ae9d068624b26660f6
Autor:
Margaret E. Ackerman, Yoonjoo Choi, Charles L Sentman, Chris Bailey-Kellogg, Casey K. Hua, Albert T Gacerez
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Understanding where antibodies recognize antigens can help define mechanisms of action and provide insights into progression of immune responses. We investigate the extent to which information about binding specificity implicitly encoded in amino aci
Autor:
Casey K. Hua, Margaret E. Ackerman
Publikováno v:
Advanced drug delivery reviews. 103
A combination of advances spanning from isolation to delivery of potent HIV-specific antibodies have begun to revolutionize understandings of antibody-mediated antiviral activity. As a result, the set of broadly neutralizing and highly protective ant