Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Casey J. Massena"'
A tractable covalent linker strategy for the production of immunogenic antigen-TLR7/8L bioconjugates
Autor:
S K Lathrop, R Schoener, Casey J. Massena, Jay T. Evans, C J Davison, Hélène G. Bazin, David J. Burkhart
Publikováno v:
Chemical Communications. 57:4698-4701
Despite the ease of production and improved safety profiles of recombinant vaccines, the inherently low immunogenicity of unadjuvanted proteins remains an impediment to their widespread adoption. The covalent tethering of TLR agonists to antigenic pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d4b828d1a754e1539371281e4c563f
https://doi.org/10.1039/d1cc00795e
https://doi.org/10.1039/d1cc00795e
Publikováno v:
Chem Rev
Using anions to induce molecular structure is a rapidly growing area of dynamic and switchable supramolecular chemistry. The emphasis of this review is on helical anion foldamers in solution, and many of the beautiful complexes described herein are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb22fe32fb768e34e2ea911f47139f4e
https://doi.org/10.1021/acs.chemrev.9b00583
https://doi.org/10.1021/acs.chemrev.9b00583
Autor:
Asia Marie S. Riel, Daniel A. Decato, Jiyu Sun, Casey J. Massena, Morly J. Jessop, Orion B. Berryman
Publikováno v:
Chemical Science. 9:5828-5836
Intramolecular hydrogen bonding directly to halogen bond donors preorganizes molecular structure and strengthens halogen bonding.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d921773c98a35ab561765f24dba0225
https://doi.org/10.1039/c8sc01973h
https://doi.org/10.1039/c8sc01973h
Autor:
Casey J. Massena, Orion B. Berryman, Vinicius R. Nascimento, Asia Marie S. Riel, Morly J. Jessop, Daniel A. Decato
Publikováno v:
Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials. 73:203-209
The halogen bond (XB) is a topical noncovalent interaction of rapidly increasing importance. The XB employs a `soft' donor atom in comparison to the `hard' proton of the hydrogen bond (HB). This difference has led to the hypothesis that XBs can form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f380e5cabd3e4b42fc3ca706402c4d43
https://doi.org/10.1107/s2052520617001809
https://doi.org/10.1107/s2052520617001809
Autor:
Stephanie K Lathrop, Casey J. Massena, Clara J. Davison, Roman Schoener, David J. Burkhart, Jay T. Evans
Publikováno v:
The Journal of Immunology. 206:102.09-102.09
When designing an effective and safe vaccine, the induction of a protective immune response to a pathogen without unacceptable levels of immunopathology is critical. The use of purified or recombinant antigens in combination with adjuvants that elici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::741adbdf19359726e433054f98b36625
https://doi.org/10.4049/jimmunol.206.supp.102.09
https://doi.org/10.4049/jimmunol.206.supp.102.09
Autor:
Stephanie K Lathrop, Casey J Massena, Clara J Davison, Roman Schoener, David J Burkhart, Jay T Evans
Publikováno v:
The Journal of Immunology. 204:245.8-245.8
When designing an effective and safe vaccine, inducing a protective immune response to a pathogen without also inducing unacceptable levels of immunopathology is a major challenge. One promising strategy is the use of purified or recombinant antigens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edc34519316ea2cb2cc3a23991a740c8
https://doi.org/10.4049/jimmunol.204.supp.245.8
https://doi.org/10.4049/jimmunol.204.supp.245.8
Publikováno v:
Angewandte Chemie (International ed. in English). 57(49)
Anion-templated helical structures are emerging as a dynamic and tractable class of supramolecules that exhibit anion-switchable self-assembly. We present the first kinetic studies of an anion helicate by utilizing halogen-bonding m-arylene-ethynylen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8f9d3833322e398c53915991ec2b66
https://pubmed.ncbi.nlm.nih.gov/30324741
https://pubmed.ncbi.nlm.nih.gov/30324741
Autor:
Casey J. Massena, George Francis Neuhaus, Orion B. Berryman, Asia Marie S. Riel, Daniel A. Decato
Publikováno v:
Chemical Communications. 51:1417-1420
(1)H NMR spectroscopic and X-ray crystallographic investigations of a 1,3-bis(4-ethynyl-3-iodopyridinium)benzene scaffold with perrhenate reveal strong halogen bonding in solution, and bidentate association in the solid state. A nearly isostructural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3394ea3debf9c3830133e37aae151873
https://doi.org/10.1039/c4cc09242b
https://doi.org/10.1039/c4cc09242b
Autor:
Casey J. Massena, Ariana M. Rose, Enrique Martin Rodriguez, Orion B. Berryman, Daniel A. Decato, Nicholas B. Wageling
The self-assembly of higher-order anion helicates in solution remains an elusive goal. Herein, we present the first triple helicate to encapsulate iodide in organic and aqueous media as well as the solid state. The triple helicate self-assembles from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041c98392ae9c315e9f5ffd79df1b74e
https://europepmc.org/articles/PMC5155591/
https://europepmc.org/articles/PMC5155591/
Autor:
Morly J. Jessop, Casey J. Massena, Asia Marie S. Riel, Daniel A. Decato, Jiyu Sun, Orion B. Berryman
Publikováno v:
Chemical Science
Natural and synthetic molecules use weak noncovalent forces to preorganize structure and enable remarkable function. Herein, we introduce the intramolecular hydrogen bonded–halogen bond (HB–XB) as a novel method to preorganize halogen bonding (XB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cc7e003f4341f68a63ba654dc9fe45
https://doi.org/10.1039/c8sc90145g
https://doi.org/10.1039/c8sc90145g