Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Casey H. Zhang"'
Autor:
Shamayeeta Ray, Samuel P Berry, Eric A Wilson, Casey H Zhang, Mrinal Shekhar, Abhishek Singharoy, Rachelle Gaudet
Publikováno v:
eLife, Vol 12 (2023)
Transporters of the Nramp (Natural resistance-associated macrophage protein) family import divalent transition metal ions into cells of most organisms. By supporting metal homeostasis, Nramps prevent diseases and disorders related to metal insufficie
Externí odkaz:
https://doaj.org/article/31a6a8e80ee44293aea58786ccac961d
Autor:
Aaron T Bozzi, Christina M Zimanyi, John M Nicoludis, Brandon K Lee, Casey H Zhang, Rachelle Gaudet
Publikováno v:
eLife, Vol 8 (2019)
Nramp family transporters—expressed in organisms from bacteria to humans—enable uptake of essential divalent transition metals via an alternating-access mechanism that also involves proton transport. We present high-resolution structures of Deino
Externí odkaz:
https://doaj.org/article/2ffaf0b83ca3479bb191db679e73d90c
Autor:
Shamayeeta Ray, Samuel P. Berry, Eric A. Wilson, Casey H. Zhang, Mrinal Shekhar, Abhishek Singharoy, Rachelle Gaudet
Transporters of the Nramp (Natural resistance-associated macrophage protein) family import divalent transition metal ions into cells of most organisms. By supporting metal homeostasis, Nramps prevent disorders related to metal insufficiency or overlo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33217888a801279e2a18f2045f8fd2c4
https://doi.org/10.1101/2022.09.08.507188
https://doi.org/10.1101/2022.09.08.507188
Autor:
Jon M. Davison, Masayuki Watanabe, Robert D. Odze, Gad Getz, Chip Stewart, Katie S. Nason, Hideo Baba, Casey H Zhang, Kunal Jajoo, Lili Sun, Chunyang Bao, Gregory J. Brunette, Richard W. Tourdot, Kenneth K. Wang, Agoston T. Agoston, Yu Imamura, Adam J. Bass, Stachler M
Complex chromosomal alterations are a hallmark of advanced cancers but rarely seen in normal tissue. The progression of precancerous lesions to malignancy is often accompanied by increasing complexity of chromosomal alterations that can drive their t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e016684819e34fc022ab8ed34dfac207
https://doi.org/10.1101/2021.03.26.437288
https://doi.org/10.1101/2021.03.26.437288
Autor:
Su-Jie Zhu, Je-Luen Li, Pelin Ayaz, Yibing Shan, Peng Zhao, Casey H Zhang, Xin Huang, Xiao-E Yan, Cai-Hong Yun, Ya-Chuang Wu, Ling Liang, David E. Shaw, Hwan Geun Choi
Publikováno v:
Journal of medicinal chemistry. 63(15)
AZD9291 (Osimertinib) is highly effective in treating EGFR-mutated non-small-cell lung cancers (NSCLCs) with T790M-mediated drug resistance. Despite the remarkable success of AZD9291, its binding pose with EGFR T790M remains unclear. Here, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0afa5d6f6cda310b4335c9a9e772cb59
https://pubmed.ncbi.nlm.nih.gov/32672461
https://pubmed.ncbi.nlm.nih.gov/32672461
Autor:
Christina M Zimanyi, Casey H Zhang, Aaron T. Bozzi, Brandon Lee, John M. Nicoludis, Rachelle Gaudet
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Nramp family transporters—expressed in organisms from bacteria to humans—enable uptake of essential divalent transition metals via an alternating-access mechanism that also involves proton transport. We present high-resolution structures of Deino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463ec2954e1698b190f0c7033de4bf93
http://europepmc.org/articles/PMC6398981
http://europepmc.org/articles/PMC6398981
Autor:
Y. Li, Chip Stewart, Young Seok Ju, Peter J. Campbell, Steve Schumacher, James E. Haber, Jeremiah Wala, Marcin Imielinski, Rameen Beroukhim, Joachim Weischenfeldt, Nicola D. Roberts, Xiaotong Yao, David Craft, Casey H Zhang, Ofer Shapira, Jose M. C. Tubio
Cancer cells can acquire profound alterations to the structure of their genomes, including rearrangements that fuse distant DNA breakpoints. We analyze the distribution of somatic rearrangements across the cancer genome, using whole-genome sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd913ca2a346e07b736170b420b880d
Autor:
Christina M Zimanyi, John M. Nicoludis, Lukas B. Bane, Aaron T. Bozzi, Brandon Lee, Casey H Zhang, Rachelle Gaudet
Publikováno v:
Biophysical Journal. 116:169a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89bef26ca774da533628134cf366b88f
https://doi.org/10.1016/j.bpj.2018.11.941
https://doi.org/10.1016/j.bpj.2018.11.941