Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Casey F. Pulliam"'
Autor:
Kranti A. Mapuskar, Casey F. Pulliam, Ann Tomanek-Chalkley, Prerna Rastogi, Hsiang Wen, Sanjana Dayal, Benjamin R. Griffin, Diana Zepeda-Orozco, Amy L. Sindler, Carryn M. Anderson, Robert Beardsley, Eugene P. Kennedy, Douglas R. Spitz, Bryan G. Allen
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103022- (2024)
Purpose: Cisplatin contributes to acute kidney injury (AKI) and chronic kidney disease (CKD) that occurs with greater frequency and severity in older patients. Age-associated cisplatin sensitivity in human fibroblasts involves increased mitochondrial
Externí odkaz:
https://doaj.org/article/700536df35bc4b5690c5fab7c5eab07c
Autor:
Khaliunaa Bayanbold, Mekhla Singhania, Melissa A. Fath, Charles C. Searby, Jeffrey M. Stolwijk, John B. Henrich, Casey F. Pulliam, Joshua D. Schoenfeld, Kranti A. Mapuskar, Sei Sho, Joseph M. Caster, Bryan G. Allen, Garry R. Buettner, Maria Spies, Prabhat C. Goswami, Michael S. Petronek, Douglas R. Spitz
Publikováno v:
Antioxidants, Vol 12, Iss 11, p 2005 (2023)
The intracellular redox-active labile iron pool (LIP) is weakly chelated and available for integration into the iron metalloproteins that are involved in diverse cellular processes, including cancer cell-specific metabolic oxidative stress. Abnormal
Externí odkaz:
https://doaj.org/article/528679c8946943c59f5691686a352e09
Autor:
Kranti A. Mapuskar, Casey F. Pulliam, Diana Zepeda-Orozco, Benjamin R. Griffin, Muhammad Furqan, Douglas R. Spitz, Bryan G. Allen
Publikováno v:
Antioxidants, Vol 12, Iss 9, p 1728 (2023)
Cisplatin, a potent chemotherapeutic agent, is marred by severe nephrotoxicity that is governed by mechanisms involving oxidative stress, inflammation, and apoptosis pathways. The transcription factor Nrf2, pivotal in cellular defense against oxidati
Externí odkaz:
https://doaj.org/article/8263fc4547b141be827d491143e309b9
Autor:
Muhammad Furqan, Taher Abu-Hejleh, Laura M. Stephens, Stacey M. Hartwig, Sarah L. Mott, Casey F. Pulliam, Michael Petronek, John B. Henrich, Melissa A. Fath, Jon C. Houtman, Steven M. Varga, Kellie L. Bodeker, Aaron D. Bossler, Andrew M. Bellizzi, Jun Zhang, Varun Monga, Hariharasudan Mani, Marina Ivanovic, Brian J. Smith, Margaret M. Byrne, William Zeitler, Brett A. Wagner, Garry R. Buettner, Joseph J. Cullen, John M. Buatti, Douglas R. Spitz, Bryan G. Allen
Publikováno v:
Redox Biology, Vol 53, Iss , Pp 102318- (2022)
Purpose: Platinum-based chemotherapy with or without immunotherapy is the mainstay of treatment for advanced stage non-small cell lung cancer (NSCLC) lacking a molecular driver alteration. Pre-clinical studies have reported that pharmacological ascor
Externí odkaz:
https://doaj.org/article/3029ad560b984a928c853c72d0650fca
Autor:
Yunxia O'Malley, Mitchell C. Coleman, Xingshen Sun, Junying Lei, Jianrong Yao, Casey F. Pulliam, Paige Kluz, Michael L. McCormick, Yaling Yi, Yumi Imai, John F. Engelhardt, Andrew W. Norris, Douglas R. Spitz, Aliye Uc
Publikováno v:
Advances in Redox Research, Vol 5, Iss , Pp 100040- (2022)
Cystic fibrosis-related diabetes (CFRD) is one the most common comorbidities in cystic fibrosis (CF). Pancreatic oxidative stress has been postulated in the pathogenesis of CFRD, but no studies have been done to show an association. The main obstacle
Externí odkaz:
https://doaj.org/article/522cd40a4710415fae812e3ff30a32cd
Autor:
Barrett D Allen, Yasaman Alaghband, Eniko A Kramár, Ning Ru, Benoit Petit, Veljko Grilj, Michael S Petronek, Casey F Pulliam, Rachel Y Kim, Ngoc-Lien Doan, Janet E Baulch, Marcelo A Wood, Claude Bailat, Douglas R Spitz, Marie-Catherine Vozenin, Charles L Limoli
Publikováno v:
Neuro-oncology, vol 25, iss 5
Background Ultrahigh dose-rate radiotherapy (FLASH-RT) affords improvements in the therapeutic index by minimizing normal tissue toxicities without compromising antitumor efficacy compared to conventional dose-rate radiotherapy (CONV-RT). To investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df719d4039ee2bb7f6d456c5e23cd2b1
https://escholarship.org/uc/item/56b7527q
https://escholarship.org/uc/item/56b7527q
Autor:
Gopi S. Gadupudi, James Watt, Casey F. Pulliam, Martin J. J. Ronis, Ashlee E Williams, Alexander W. Alund, Larry W. Robertson, Ezazul Haque
Publikováno v:
Arch Toxicol
Skeletal toxicity has been reported following exposure to polychlorinated biphenyl (PCB) mixtures. However, molecular mechanisms remain poorly understood. We exposed groups of male 4–5-week-old Sprague–Dawley rats to 3,3′, 4, 4′, 5-pentachlor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9c216eef07cf73bb1537296a9b2b37
https://doi.org/10.1007/s00204-019-02645-w
https://doi.org/10.1007/s00204-019-02645-w
Autor:
M.M. Hasibuzzaman, Kranti A. Mapuskar, Bryan G. Allen, Mohammed M. Milhem, Benjamin J. Miller, Casey F. Pulliam, Jessica E. Goetz, Emily J. Steinbach, Samuel N. Rodman, Douglas R. Spitz, Mitchell C. Coleman, C.M. Callaghan, Varun Monga, Michael S. Petronek
Publikováno v:
Cancers, Vol 12, Iss 2258, p 2258 (2020)
Cancers
Cancers
Historically, patients with localized soft tissue sarcomas (STS) of the extremities would undergo limb amputation. It was subsequently determined that the addition of radiation therapy (RT) delivered prior to (neoadjuvant) or after (adjuvant) a limb-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5bff50372af0d291450f8cb53b67c3c
https://www.mdpi.com/2072-6694/12/8/2258
https://www.mdpi.com/2072-6694/12/8/2258
Autor:
Luis Del Valle, Casey F. Pulliam, Derrick R. Samuelson, Martin J. J. Ronis, David A. Welsh, Kartik Shankar, Magnus Ingelman-Sundberg, Simonetta Friso, Kim Brint Pedersen, Kelly E. Mercer, Christopher M. Taylor
Publikováno v:
Chem Biol Interact
We have previously demonstrated promotion of diethylnitrosamine (DEN) initiated liver tumorigenesis after feeding diets high in fat or ethanol (EtOH) to male mice. This was accompanied by hepatic induction of the proto-oncogene PIKE (Agap2). Switch o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47dd877866faf9df2f7eab2d4cb89f76
http://hdl.handle.net/11562/1038099
http://hdl.handle.net/11562/1038099
Autor:
David J. Orlicky, Kyle Meredith, Dennis R. Petersen, Kelly E. Mercer, Casey F. Pulliam, Martin J. J. Ronis, Colin T. Shearn, Laura Saba, Kim Brint Pedersen
Publikováno v:
Alcoholism: Clinical and Experimental Research. 42:1192-1205
BACKGROUND: Glutathione-S-transferase A4-4 (GSTA4) is a key enzyme for removal of toxic lipid peroxidation products such as 4-hydroxynonenal (4-HNE). In the current study, we examined the potential role of GSTA4 on protein carbonylation and progressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77801c831ef2c26594593286cb93be6
https://doi.org/10.1111/acer.13766
https://doi.org/10.1111/acer.13766