Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Casey C. Perley"'
Autor:
Casey C. Perley, Rebecca L. Brocato, Hua Wu, Christoph Bausch, Priya P. Karmali, Jerel B. Vega, Melanie V. Cohen, Brandon Somerville, Steven A. Kwilas, Lucia M. Principe, Joshua Shamblin, Padmanabh Chivukula, Eddie Sullivan, Jay W. Hooper
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
We explored an emerging technology to produce anti-Hantaan virus (HTNV) and anti-Puumala virus (PUUV) neutralizing antibodies for use as pre- or post-exposure prophylactics. The technology involves hyperimmunization of transchomosomic bovines (TcB) e
Externí odkaz:
https://doaj.org/article/883066dd28aa42bfa06594256c084192
Autor:
Peter T. Witkowski, Casey C. Perley, Rebecca L. Brocato, Jay W. Hooper, Christian Jürgensen, Jörg-Dieter Schulzke, Detlev H. Krüger, Roland Bücker
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Background: Hantaviruses are zoonotic agents that cause hemorrhagic fevers and are thought to be transmitted to humans by exposure to aerosolized excreta of infected rodents. Puumala virus (PUUV) is the predominant endemic hantavirus in Europe. A lar
Externí odkaz:
https://doaj.org/article/f9ae796be69e42db998b26d81e10d4ba
Autor:
Rebecca L Brocato, Louis A Altamura, Brian D Carey, Casey C Perley, Candace D Blancett, Timothy D Minogue, Jay W Hooper
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 8, p e0009592 (2021)
BackgroundSyrian hamsters infected with Andes virus (ANDV) develop a disease that recapitulates many of the salient features of human hantavirus pulmonary syndrome (HPS), including lethality. Infection of hamsters with Hantaan virus (HTNV) results in
Externí odkaz:
https://doaj.org/article/25f8804a71ba4e86b86bced1618d9b88
Autor:
Casey C Perley, Rebecca L Brocato, Steven A Kwilas, Sharon Daye, Alicia Moreau, Donald K Nichols, Kelly S Wetzel, Joshua Shamblin, Jay W Hooper
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216700 (2019)
Hantaan virus (HTNV) and Puumala virus (PUUV) are rodent-borne hantaviruses that are the primary causes of hemorrhagic fever with renal syndrome (HFRS) in Europe and Asia. The development of well characterized animal models of HTNV and PUUV infection
Externí odkaz:
https://doaj.org/article/e3eef374354a4c02b74d26dc84d26885
Autor:
Louis A. Altamura, Candace D. Blancett, Timothy D. Minogue, Rebecca L. Brocato, Casey C. Perley, Brian D. Carey, Jay W. Hooper
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 8, p e0009592 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Syrian hamsters infected with Andes virus (ANDV) develop a disease that recapitulates many of the salient features of human hantavirus pulmonary syndrome (HPS), including lethality. Infection of hamsters with Hantaan virus (HTNV) results i
Autor:
Casey C. Perley, Rebecca L. Brocato, Melanie V. Cohen, Brandon Somerville, Steven A. Kwilas, Lucia M. Principe, Simon Y Long, Xiankun Zeng, Jay W. Hooper, Matthew D. Josleyn
Publikováno v:
Vaccine. 39(7)
DNA vaccine evaluation in small animals is hampered by low immunogenicity when the vaccines are delivered using a needle and syringe. To overcome this technical hurdle we tested the possibility that a device developed for human intradermal medicine d
Autor:
Melanie V. Cohen, Joshua D. Shamblin, Jay W. Hooper, Eddie Sullivan, Rebecca L. Brocato, Padmanabh Chivukula, Lucia M. Principe, Brandon Somerville, Christoph L Bausch, Steven A. Kwilas, Jerel Vega, Priya Karmali, Hua Wu, Casey C. Perley
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Frontiers in Microbiology
Frontiers in Microbiology
We explored an emerging technology to produce anti-Hantaan virus (HTNV) and anti-Puumala virus (PUUV) neutralizing antibodies for use as pre- or post-exposure prophylactics. The technology involves hyperimmunization of transchomosomic bovines (TcB) e
Autor:
Jay W. Hooper, Alicia M. Moreau, Sharon P. Daye, Joshua D. Shamblin, Casey C. Perley, Kelly S. Wetzel, Donald K. Nichols, Rebecca L. Brocato, Steven A. Kwilas
Publikováno v:
PLOS ONE
PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0216700 (2019)
PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0216700 (2019)
Hantaan virus (HTNV) and Puumala virus (PUUV) are rodent-borne hantaviruses that are the primary causes of hemorrhagic fever with renal syndrome (HFRS) in Europe and Asia. The development of well characterized animal models of HTNV and PUUV infection
Autor:
Casey C. Perley, Richard Frothingham, Norman L. Letvin, Eva M. Click, Birgit Korioth-Schmitz, Sunhee Lee, Jaimie D. Sixsmith
Publikováno v:
Vaccine. 33(42):5715-5722
Background A recombinant Mycobacterium bovis BCG (rBCG) vector expressing HIV transgenes is an attractive candidate as a dual vaccine against HIV and TB. However, pre-existing immune responses to mycobacteria may influence immune responses to rBCG. W
Autor:
Jörg-Dieter Schulzke, Roland Bücker, Christian Jürgensen, Rebecca L. Brocato, Peter T. Witkowski, Casey C. Perley, Detlev H. Krüger, Jay W. Hooper
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 8 (2017)
Frontiers in Microbiology, Vol 8 (2017)
Background: Hantaviruses are zoonotic agents that cause hemorrhagic fevers and are thought to be transmitted to humans by exposure to aerosolized excreta of infected rodents. Puumala virus (PUUV) is the predominant endemic hantavirus in Europe. A lar