Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Casey C, Case"'
Publikováno v:
Cell Transplantation, Vol 19 (2010)
Cell transplantation is a promising treatment strategy for many neurological disorders, including stroke, which can target multiple therapeutic mechanisms in a sustained fashion. We investigated the ability of human mesenchymal stromal cells (MSCs) a
Externí odkaz:
https://doaj.org/article/4c26e3c2ba5245059fc708d9acb2d93a
Autor:
Casey C. Case, Kevin Nishimoto, Edward D. Wirth, Debasish Sen, Jane S. Lebkowski, William Blum, Laurence Elias, Hanna Jean Khoury, Patrick S. Stiff, Anita Reddy, John F. DiPersio, Robert H. Collins
Publikováno v:
Cancer. 123:3061-3072
BACKGROUND Telomerase activity in leukemic blasts frequently is increased among patients with high-risk acute myeloid leukemia (AML). In the current study, the authors evaluated the feasibility, safety, immunogenicity, and therapeutic potential of hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6807fef98d206bb4c93b6aee36674d2
https://doi.org/10.1002/cncr.30696
https://doi.org/10.1002/cncr.30696
Autor:
Anthony S. Kim, Douglas Kondziolka, Neil E. Schwartz, Jeremiah N. Johnson, Gary K. Steinberg, Casey C. Case, Ernest Yankee, Gene Poggio, Michael McGrogan, Damien Bates, Lawrence R. Wechsler, L. Dade Lunsford
Publikováno v:
Journal of neurosurgery.
OBJECTIVEThe aim of this study was to evaluate the safety and clinical outcomes associated with stereotactic surgical implantation of modified bone marrow–derived mesenchymal stem cells (SB623) in patients with stable chronic ischemic stroke.METHOD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65dc8e62d845b00b658ffe49c75ac29
https://pubmed.ncbi.nlm.nih.gov/30497166
https://pubmed.ncbi.nlm.nih.gov/30497166
Autor:
Amy B. Manning-Boğ, Carla Campos, Vivian P. Chou, Michael McGrogan, Donato A. Di Monte, Casey C. Case, Alimohammed S. Moalem, Ciara C. Tate
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 11:1835-1843
Regenerative medicine for the treatment of motor features in Parkinson's disease (PD) is a promising therapeutic option. Donor cells can simultaneously address multiple pathological mechanisms while responding to the needs of the host tissue. Previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae34fbc44cc56d3f9186b8d5b4976aaf
https://doi.org/10.1002/term.2081
https://doi.org/10.1002/term.2081
Autor:
Martin Oudega, Femke Streijger, David S.K. Magnuson, Martin Marsala, Andrea J. Mothe, Caitlin E. Hill, Elizabeth J. Bradbury, Armin Blesch, Xiao Ming Xu, Simon W. Moore, Aileen J. Anderson, Lyn B. Jakeman, John D. Houle, Wolfram Tetzlaff, Michael S. Beattie, Candace L. Floyd, Oswald Steward, Naomi Kleitman, Casey C. Case, Mark Bacon, Arthur Brown, James W. Fawcett, Samuel David, Giles W. Plant, Alexander Sasha Rabchevsky, Jeffery D. Kocsis, Raymond W. Colburn, Jerry Silver, James D. Guest, Linda Jones, Paul Lu, Adam R. Ferguson, Jan M. Schwab, Jacqueline C. Bresnahan, Brian K. Kwon, John C. Gensel, Itzhak Fischer, Nick D. Jeffery
Publikováno v:
Experimental Neurology. 269:154-168
Large animal and primate models of spinal cord injury (SCI) are being increasingly utilized for the testing of novel therapies. While these represent intermediary animal species between rodents and humans and offer the opportunity to pose unique rese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece1bc2a7d1fec22dae5386d5fd5896a
https://doi.org/10.1016/j.expneurol.2015.04.008
https://doi.org/10.1016/j.expneurol.2015.04.008
Autor:
Hanna J, Khoury, Robert H, Collins, William, Blum, Patrick S, Stiff, Laurence, Elias, Jane S, Lebkowski, Anita, Reddy, Kevin P, Nishimoto, Debasish, Sen, Edward D, Wirth, Casey C, Case, John F, DiPersio
Publikováno v:
Cancer. 123(16)
Telomerase activity in leukemic blasts frequently is increased among patients with high-risk acute myeloid leukemia (AML). In the current study, the authors evaluated the feasibility, safety, immunogenicity, and therapeutic potential of human telomer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a9e7c0f36519b9f1edbf3e10308607e
https://pubmed.ncbi.nlm.nih.gov/28411378
https://pubmed.ncbi.nlm.nih.gov/28411378
Publikováno v:
STEM CELLS Translational Medicine. 2:223-232
Transplanting mesenchymal stromal cells (MSCs) or their derivatives in a neurodegenerative environment is believed to be beneficial because of the trophic support, migratory guidance, and neurogenic stimuli they provide. There is a growing need for i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213fc55619753a3b70ea5cd12b92d556
https://doi.org/10.5966/sctm.2012-0119
https://doi.org/10.5966/sctm.2012-0119
Publikováno v:
Advances in Neuroimmune Biology. 4:177-185
Adult marrow derived mesenchymal stromal cells are currently in clinical trials for various neurodegenerative diseases. Through secretion of soluble and insoluble trophic factors, mesenchymal stromal cells promote the endogenous stem and progenitor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af7408480a3ef24f41dd23fec764c487
https://doi.org/10.3233/nib-130064
https://doi.org/10.3233/nib-130064
Autor:
Ernest Yankee, Lawrence R. Wechsler, Douglas Kondziolka, Michael McGrogan, Neil E. Schwartz, L. Dade Lunsford, Bill King, Gary K. Steinberg, Damien Bates, Jeremiah N. Johnson, Casey C. Case, Maria L. Coburn, Anthony S. Kim, Julia B Billigen
Publikováno v:
Stroke. 47(7)
Background and Purpose— Preclinical data suggest that cell-based therapies have the potential to improve stroke outcomes. Methods— Eighteen patients with stable, chronic stroke were enrolled in a 2-year, open-label, single-arm study to evaluate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ad2347c51a75c8477af03347c1d8b3
https://pubmed.ncbi.nlm.nih.gov/27926699
https://pubmed.ncbi.nlm.nih.gov/27926699
Autor:
H Steve, Zhang, Dingang, Liu, Yan, Huang, Stefan, Schmidt, Reed, Hickey, Dmitry, Guschin, Haili, Su, Ion S, Jovin, Mike, Kunis, Sarah, Hinkley, Yuxin, Liang, Linda, Hinh, S Kaye, Spratt, Casey C, Case, Edward J, Rebar, Barbara E, Ehrlich, Barbara, Ehrlich, Philip D, Gregory, Frank J, Giordano
Publikováno v:
Molecular Therapy
Selective inhibition of disease-related proteins underpins the majority of successful drug–target interactions. However, development of effective antagonists is often hampered by targets that are not druggable using conventional approaches. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf6d75f77ecc7bd1ea7a45b7b9474c4
http://europepmc.org/articles/PMC3412484
http://europepmc.org/articles/PMC3412484