Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Casey A. Chamberlain"'
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 8 (2022)
An integrated evaluation of the tissue distribution and pharmacodynamic properties of a therapeutic is essential for successful translation to the clinic. To date, however, cost-effective methods to measure these parameters at the systems level in mo
Externí odkaz:
https://doaj.org/article/4c20179e5bb64a0699c5531d951d7e9a
Autor:
Hoda Safari Yazd, Vanessa Y. Rubio, Casey A. Chamberlain, Richard A. Yost, Timothy J. Garrett
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 20, Iss , Pp 11-24 (2021)
Introduction: Intellectual disorders involving deletions of the X chromosome present a difficult task in the determination of a connection between symptoms and metabolites that could lead to treatment options. One specific disorder of X-chromosomal d
Externí odkaz:
https://doaj.org/article/8cc8834011b2435e8fad6733b993e682
Publikováno v:
Metabolites, Vol 11, Iss 5, p 308 (2021)
Paper spray ionization mass spectrometry (PSI-MS) is a direct MS analysis technique with several reported bacterial metabolomics applications. As with most MS-based bacterial studies, all currently reported PSI-MS bacterial analyses have focused on t
Externí odkaz:
https://doaj.org/article/53d18024286041c6ab044fb0f117943f
Publikováno v:
Metabolites, Vol 10, Iss 10, p 405 (2020)
Oxalobacter formigenes has been investigated for years due to its proposed ability to produce a secretagogue compound that initiates net intestinal oxalate secretion, thereby theoretically reducing circulating oxalate and risk of kidney stone formati
Externí odkaz:
https://doaj.org/article/78a2196f2d58425c97eb8c10933a8cc7
Autor:
Richard A. Yost, Vanessa Y. Rubio, Hoda Safari Yazd, Timothy J. Garrett, Casey A. Chamberlain
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 20, Iss, Pp 11-24 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab
Highlights • LC-HRMS Metabolomics and lipidomics applied in X-chromosome deletion disorders. • Partial or complete deletion of the X chromosome is a very rare condition. • Neural progenitor cells from a patient with a 7.3 megabase deletion at X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09943261b4913c7a499e6c4602a9449
http://www.sciencedirect.com/science/article/pii/S2667145X21000092
http://www.sciencedirect.com/science/article/pii/S2667145X21000092
Publikováno v:
Anal Bioanal Chem
Diseases of oxalate, such as nephrolithiasis and primary hyperoxaluria, affect a significant portion of the US population and have limited treatment options. Oxalobacter formigenes, an obligate oxalotrophic bacterium in the mammalian intestine, has g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc7b7ffc6dca04b2285e4c17abbd6fe
https://doi.org/10.1007/s00216-019-01639-y
https://doi.org/10.1007/s00216-019-01639-y
Publikováno v:
Metabolomics. 17
Studies investigating crop resistance to abiotic and biotic stress have largely focused on plant responses to singular forms of stress and individual biochemical pathways that only partially represent stress responses. Thus, combined abiotic and biot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6960db39b66932c69351e3208f8c0e22
https://doi.org/10.1007/s11306-020-01739-2
https://doi.org/10.1007/s11306-020-01739-2
Publikováno v:
Metabolomics. 16
In the search for new potential therapies for pathologies of oxalate, such as kidney stone disease and primary hyperoxaluria, the intestinal microbiome has generated significant interest. Resident oxalate-degrading bacteria inhabit the gastrointestin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5acf1f6c2d33ba6c218928e95c72f279
https://doi.org/10.1007/s11306-020-01747-2
https://doi.org/10.1007/s11306-020-01747-2
Publikováno v:
Metabolites, Vol 10, Iss 405, p 405 (2020)
Metabolites
Volume 10
Issue 10
Metabolites
Volume 10
Issue 10
Oxalobacter formigenes has been investigated for years due to its proposed ability to produce a secretagogue compound that initiates net intestinal oxalate secretion, thereby theoretically reducing circulating oxalate and risk of kidney stone formati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadadcd2b82b12c25a87aff288ea404c
https://www.mdpi.com/2218-1989/10/10/405
https://www.mdpi.com/2218-1989/10/10/405
Autor:
Alexandra Guevara, Timothy J. Garrett, Arlan L. Rosenbloom, Richard A. Yost, Clive Wasserfall, Vanessa Y. Rubio, Mark A. Atkinson, Jaime Guevara-Aguirre, Casey A. Chamberlain
Publikováno v:
Diabetes. 69
Laron syndrome (LS) is a rare autosomal recessive growth hormone (GH) insensitivity condition due to GH receptor mutation, and with phenotypic features likened to GH deficiency. The incidence of LS in Ecuador is very high and has gained worldwide att
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b6a365877fbd08fff82b28c68a1e167
https://doi.org/10.2337/db20-195-lb
https://doi.org/10.2337/db20-195-lb