Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Casey A Maguire"'
Autor:
Melanie Herre, Kalyani Vemuri, Jessica Cedervall, Stefanie Nissl, Falk Saupe, Jacob Micallef, Henrik Lindman, Casey A. Maguire, George Tetz, Victor Tetz, Anna‐Karin Olsson
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 10, Pp 454-466 (2024)
Abstract Neutrophil extracellular traps (NETs) have been implicated in the pathology of various inflammatory conditions. In cancer, NETs have been demonstrated to induce systemic inflammation, impair peripheral vessel and organ function and promote m
Externí odkaz:
https://doaj.org/article/60eac28cad7e4664b5ec44156895a97e
Autor:
Jonathan Dashkoff, Eli P Lerner, Nhi Truong, Jacob A Klickstein, Zhanyun Fan, Dakai Mu, Casey A Maguire, Bradley T Hyman, Eloise Hudry
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
The capacity of certain adeno-associated virus (AAV) vectors to cross the blood–brain barrier after intravenous delivery offers a unique opportunity for noninvasive brain delivery. However, without a well-tailored system, the use of a peripheral ro
Externí odkaz:
https://doaj.org/article/268aaa1355464350a8486123556bc6b4
Autor:
Matheus HW Crommentuijn, Rami Kantar, David P Noske, W Peter Vandertop, Christian E Badr, Thomas Würdinger, Casey A Maguire, Bakhos A Tannous
Publikováno v:
Molecular Therapy: Oncolytics, Vol 3, Iss C (2016)
Adeno-associated virus (AAV) vectors expressing tumoricidal genes injected directly into brain tumors have shown some promise, however, invasive tumor cells are relatively unaffected. Systemic injection of AAV9 vectors provides widespread delivery to
Externí odkaz:
https://doaj.org/article/0eb069b80fae478a93e6bfd5021c5fbc
Autor:
Shilpa Prabhakar, Roberta L. Beauchamp, Pike See Cheah, Akiko Yoshinaga, Edwina Abou Haidar, Sevda Lule, Gayathri Mani, Katia Maalouf, Anat Stemmer-Rachamimov, David H. Jung, D. Bradley Welling, Marco Giovannini, Scott R. Plotkin, Casey A. Maguire, Vijaya Ramesh, Xandra O. Breakefield
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101262- (2024)
Externí odkaz:
https://doaj.org/article/3e5ab6a0da2740adbac015462c8c83b4
Autor:
Casey A Maguire, M Sarah Bovenberg, Matheus HW Crommentuijn, Johanna M Niers, Mariam Kerami, Jian Teng, Miguel Sena-Esteves, Christian E Badr, Bakhos A Tannous
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Bioluminescence imaging (BLI) has shown to be crucial for monitoring in vivo biological processes. So far, only dual bioluminescence imaging using firefly (Fluc) and Renilla or Gaussia (Gluc) luciferase has been achieved due to the lack of availabili
Externí odkaz:
https://doaj.org/article/0ff1524993974309a9dd9871c2c2d944
Autor:
Walter W Chen, Leonora Balaj, Linda M Liau, Michael L Samuels, Steve K Kotsopoulos, Casey A Maguire, Lori LoGuidice, Horacio Soto, Matthew Garrett, Lin Dan Zhu, Sarada Sivaraman, Clark Chen, Eric T Wong, Bob S Carter, Fred H Hochberg, Xandra O Breakefield, Johan Skog
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Development of biofluid-based molecular diagnostic tests for cancer is an important step towards tumor characterization and real-time monitoring in a minimally invasive fashion. Extracellular vesicles (EVs) are released from tumor cells into body flu
Externí odkaz:
https://doaj.org/article/c4e8022ea0894cfc81d7b563a35d26a8
Autor:
Miguel C. Santoscoy, Paula Espinoza, Demitri De La Cruz, Mohammed Mahamdeh, Jacqueline R. Starr, Nikita Patel, Casey A. Maguire
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 532-540 (2023)
Adeno-associated virus (AAV) vectors are currently the most efficient option for intracranial gene therapies to treat neurodegenerative disease. Increased efficacy and safety will depend upon robust and specific expression of therapeutic genes into t
Externí odkaz:
https://doaj.org/article/8b58260a419b4fa597e241a037e22355
Autor:
Shilpa Prabhakar, Roberta L. Beauchamp, Pike See Cheah, Akiko Yoshinaga, Edwina Abou Haidar, Sevda Lule, Gayathri Mani, Katia Maalouf, Anat Stemmer-Rachamimov, David H. Jung, D. Bradley Welling, Marco Giovannini, Scott R. Plotkin, Casey A. Maguire, Vijaya Ramesh, Xandra O. Breakefield
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 169-180 (2022)
Loss of function of the neurofibromatosis type 2 (NF2) tumor suppressor gene leads to the formation of schwannomas, meningiomas, and ependymomas, comprising ∼50% of all sporadic cases of primary nervous system tumors. NF2 syndrome is an autosomal d
Externí odkaz:
https://doaj.org/article/7beaec1f53b24b3a8b2e347e32d796ca
Autor:
Maryna V. Ivanchenko, Killian S. Hanlon, Daniel M. Hathaway, Alex J. Klein, Cole W. Peters, Yaqiao Li, Panos I. Tamvakologos, Josette Nammour, Casey A. Maguire, David P. Corey
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 382-398 (2021)
Gene therapy strategies using adeno-associated virus (AAV) vectors to treat hereditary deafnesses have shown remarkable efficacy in some mouse models of hearing loss. Even so, there are few AAV capsids that transduce both inner and outer hair cells
Externí odkaz:
https://doaj.org/article/475fe1182acd4ea6b521c663f3fd4d5c
Autor:
Bence György, Elise J. Meijer, Maryna V. Ivanchenko, Kelly Tenneson, Frederick Emond, Killian S. Hanlon, Artur A. Indzhykulian, Adrienn Volak, K. Domenica Karavitaki, Panos I. Tamvakologos, Mark Vezina, Vladimir K. Berezovskii, Richard T. Born, Maureen O’Brien, Jean-François Lafond, Yvan Arsenijevic, Margaret A. Kenna, Casey A. Maguire, David P. Corey
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss , Pp 1-13 (2019)
Hereditary hearing loss often results from mutation of genes expressed by cochlear hair cells. Gene addition using AAV vectors has shown some efficacy in mouse models, but clinical application requires two additional advances. First, new AAV capsids
Externí odkaz:
https://doaj.org/article/6758ea888ad8422f9ec07444e4da3682