Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Casey C. McComas"'
Autor:
Richard Soll, Peng Li, Jin Wu, Peter T. Meinke, David B. Olsen, Anandan Palani, Ajay Ummat, Wei Chang, Nigel J. Liverton, M. Katharine Holloway, Xuanjia Peng, Casey C. Mccomas, Jie Wu, Charles A. Lesburg, Nicolas Zorn, Steven W. Ludmerer
Publikováno v:
ChemMedChem. 12:1436-1448
Studies directed at developing a broadly acting non-nucleoside inhibitor of HCV NS5B led to the discovery of a novel structural class of 5-aryl benzofurans that simultaneously interact with both the palm I and palm II binding regions. An initial cand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b371b4c60faeab68df38952d1991a2
https://doi.org/10.1002/cmdc.201700228
https://doi.org/10.1002/cmdc.201700228
Autor:
Paige E. Mahaney, Puwen Zhang, Casey C. McComas, Eugene John Trybulski, Ani Sarkahian, Nicole R. Sullivan, Liza Leventhal, Albert J. Uveges, Lisa Nogle, William L. Watts, An T. Vu
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:8455-8466
Compounds with a combination of norepinephrine and serotonin reuptake inhibition have been approved in the US and Europe for a number of indications, including major depressive disorder and pain disorders such as diabetic neuropathy and fibromyalgia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf20c6072374d9fa11c4b618abfe2fa
https://doi.org/10.1016/j.bmc.2006.08.039
https://doi.org/10.1016/j.bmc.2006.08.039
Autor:
Peter T. Meinke, Nigel J. Liverton, Jin Wu, Jie Wu, Richard Soll, Wei Chang, Anandan Palani, M. Katharine Holloway, Casey C. Mccomas, Peng Li, Charles A. Lesburg, Xuanjia Peng, Ajay Ummat, Nicolas Zorn, David B. Olsen, Steven W. Ludmerer
Publikováno v:
ChemMedChem. 12:1418-1418
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8144ddbf750fbad5f0fa60a1c1e9cdd9
https://doi.org/10.1002/cmdc.201700490
https://doi.org/10.1002/cmdc.201700490
Publikováno v:
Organometallics. 19:2853-2857
The synthesis of metal complexes with anionic η5-pyrrole ligands is generally complicated by the free nitrogen lone pair. Methods are reported for the synthesis of two types of neutral η5-tetrameth...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aefc758ee49229b5a43239e4ea23af2
https://doi.org/10.1021/om000189n
https://doi.org/10.1021/om000189n
Autor:
Casey C. McComas, David L. Van Vranken
Publikováno v:
Tetrahedron Letters. 40:8039-8043
A general two-step procedure for the reduction of indoles to the corresponding 4,5,6,7-tetrahydroindoles has been developed. A regioselective Birch reduction followed by catalytic hydrogenation is employed to accomplish this transformation. Yields fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33666d9d8768e408f4802ef820a562d5
https://doi.org/10.1016/s0040-4039(99)01687-1
https://doi.org/10.1016/s0040-4039(99)01687-1
Autor:
Amir Weitz, Mordecai Rabinovitz, Casey C. McComas, Michael D. Best, Matthew S. Bratcher, Elad Shabtai, Lawrence T. Scott
Publikováno v:
Chemistry - A European Journal. 4:234-239
The fullerene fragment 1 (C28H14) gives a paratropic dianion and a diatropic tetraanion on alkali metal reduction, whereas the C30H14 hydrocarbon 2, which contains just one more ring from the C60 network, gives a diatropic dianion and a paratropic te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f111b477ef44db3ad44bd95a043b5a4
https://doi.org/10.1002/(sici)1521-3765(19980210)4:2<234::aid-chem234>3.0.co
https://doi.org/10.1002/(sici)1521-3765(19980210)4:2<234::aid-chem234>3.0.co
Autor:
David L. Van Vranken, Casey C. McComas
Publikováno v:
Tetrahedron Letters. 44:8203-8205
Thia-Sommelet dearomatization reactions of benzylsulfonium ylides can create highly congested quaternary centers. Chiral bis-lithium amide bases were shown to effect enantiotopic deprotonation of benzylsulfonium ions, leading to thia-Sommelet rearran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7eae665f17ad4752d28abd28cdb09d
https://doi.org/10.1016/j.tetlet.2003.09.079
https://doi.org/10.1016/j.tetlet.2003.09.079
Autor:
Michael Marella, Christine Huselton, Edward Melenski, Casey C. McComas, Richard C. Winneker, Cheryl Mugford, Jeffrey Cohen, Andrew Fensome, Matthew R. Yudt, Ov D. Slayden, Jay Wrobel
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(23)
We have developed a new series of progesterone receptor modulators based upon the 4-aryl-phenylsulfonamide. Initial work in the series afforded potent compounds with good properties, however an advanced intermediate proved to be genotoxic in a non-GL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69fd1aa8e85b46f671ceb8fa21e208c6
https://pubmed.ncbi.nlm.nih.gov/23079530
https://pubmed.ncbi.nlm.nih.gov/23079530
Autor:
David L. Van Vranken, Casey C. McComas
Publikováno v:
ChemInform. 31
A general two-step procedure for the reduction of indoles to the corresponding 4,5,6,7-tetrahydroindoles has been developed. A regioselective Birch reduction followed by catalytic hydrogenation is employed to accomplish this transformation. Yields fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6a3a5c87033cd477eca06e3503324ac
https://doi.org/10.1002/chin.200008136
https://doi.org/10.1002/chin.200008136
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a64563f6c317647b483d75ccdb0d8b30
https://doi.org/10.1002/chin.200248208
https://doi.org/10.1002/chin.200248208