Zobrazeno 1 - 10
of 611
pro vyhledávání: '"Case–control association"'
Autor:
Prachi Kukshal, Radha O Joshi, Ajay Kumar, Shadab Ahamad, Prabhatha Rashmi Murthy, Yogesh Sathe, Krishna Manohar, Soma Guhathakurta, Subramanian Chellappan
Publikováno v:
BMC Pediatrics, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Congenital Heart diseases (CHDs) account for 1/3rd of all congenital birth defects. Etiopathogenesis of CHDs remain elusive despite extensive investigations globally. Phenotypic heterogeneity witnessed in this developmental disord
Externí odkaz:
https://doaj.org/article/cca25bad0d3a47638c941bfda42d6b3a
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
ObjectiveAcute necrotizing encephalopathy (ANE) is a severe complication of infectious diseases affecting the brain and systemic organs. The main pathogenesis is cytokine storm, in which interleukin-6 (IL-6) and interleukin-10 (IL-10) are candidates
Externí odkaz:
https://doaj.org/article/e530a58e672641c8854f07696127c4da
Akademický článek
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Publikováno v:
Proceedings, Vol 36, Iss 3, Pp 01-12 (2022)
Introduction: TLR4-dependent pro-inflammatory signaling has been involved in the initiation, progression, and plaque destabilization phases of atherosclerosis which is the leading cause of MI. Aims & Objectives: To determine primarily the associat
Externí odkaz:
https://doaj.org/article/ac937e41f36648d293a1f919e547a3d9
Akademický článek
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Autor:
Na Zhu, Emilia M. Swietlik, Carrie L. Welch, Michael W. Pauciulo, Jacob J. Hagen, Xueya Zhou, Yicheng Guo, Johannes Karten, Divya Pandya, Tobias Tilly, Katie A. Lutz, Jennifer M. Martin, Carmen M. Treacy, Erika B. Rosenzweig, Usha Krishnan, Anna W. Coleman, Claudia Gonzaga-Juaregui, Allan Lawrie, Richard C. Trembath, Martin R. Wilkins, Regeneron Genetics Center, PAH Biobank Enrolling Centers’ Investigators, NIHR BioResource for Translational Research - Rare Diseases, National Cohort Study of Idiopathic and Heritable PAH, Nicholas W. Morrell, Yufeng Shen, Stefan Gräf, William C. Nichols, Wendy K. Chung
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021)
Abstract Background Pulmonary arterial hypertension (PAH) is a lethal vasculopathy characterized by pathogenic remodeling of pulmonary arterioles leading to increased pulmonary pressures, right ventricular hypertrophy, and heart failure. PAH can be a
Externí odkaz:
https://doaj.org/article/7d26217cb5954a278edcedd89f0346c6
Autor:
Amal Bouzid, Adel Tekari, Fida Jbeli, Amine Chakroun, Kirtal Hansdah, Amal Souissi, Neha Singh, Mohamed Ali Mosrati, Imen Achour, Abdelmonem Ghorbel, Ilhem Charfeddine, Puppala Venkat Ramchander, Saber Masmoudi
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Otosclerosis (OTSC) is among the most common causes of a late-onset hearing loss in adults and is characterized by an abnormal bone growth in the otic capsule. Alteration in the osteoprotegerin (OPG) expression has been suggested
Externí odkaz:
https://doaj.org/article/f0fdfec8b41144259354249c5a32eceb
Autor:
Na Zhu, Michael W. Pauciulo, Carrie L. Welch, Katie A. Lutz, Anna W. Coleman, Claudia Gonzaga-Jauregui, Jiayao Wang, Joseph M. Grimes, Lisa J. Martin, Hua He, PAH Biobank Enrolling Centers’ Investigators, Yufeng Shen, Wendy K. Chung, William C. Nichols
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-16 (2019)
Abstract Background Group 1 pulmonary arterial hypertension (PAH) is a rare disease with high mortality despite recent therapeutic advances. Pathogenic remodeling of pulmonary arterioles leads to increased pulmonary pressures, right ventricular hyper
Externí odkaz:
https://doaj.org/article/776446f435e24d23b47dd597dcf09d77
Akademický článek
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Autor:
Yongping Chen, Ruwei Ou, Lingyu Zhang, Xiaojing Gu, Xiaoqin Yuan, Qian-qian Wei, Bei Cao, Bi Zhao, Ying Wu, Huifang Shang
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Background: Impaired dopamine metabolism is associated with Parkinson’s disease (PD). Considering the overlap in the clinical and pathological characteristics between PD and multiple system atrophy (MSA), we investigated the effect of five potentia
Externí odkaz:
https://doaj.org/article/960819aba3bc4946b47bddd5ebacab88