Induced pluripotent stem cell-derived astrocytes from patients with schizophrenia exhibit an inflammatory phenotype that affects vascularization.

Autor: Trindade P; Instituto D'Or de Pesquisa e Ensino (IDOR), Rio de Janeiro, Brazil. pablotrindade@ufrj.br.; Departamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil. pablotrindade@ufrj.br., Nascimento JM; Instituto D'Or de Pesquisa e Ensino (IDOR), Rio de Janeiro, Brazil. juminardi@gmail.com.; Departamento de Bioquímica e Biologia Tecidual, Instituto de Biologia, Universidade Estadual de Campinas, Campinas, Brazil. juminardi@gmail.com.; Departamento de Biociências, Universidade Federal de São Paulo, Santos, Brazil. juminardi@gmail.com., Casas BS; Laboratory of Stem Cells & Developmental Biology, Departamento de Biología, Universidad de Chile, Santiago, Chile., Monteverde T; Laboratory of Stem Cells & Developmental Biology, Departamento de Biología, Universidad de Chile, Santiago, Chile., Gasparotto J; Instituto de Ciências Biomédicas, Universidade Federal de Alfenas, Alfenas, Minas Gerais, Brazil., Ribeiro CT; Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Devalle S; Instituto D'Or de Pesquisa e Ensino (IDOR), Rio de Janeiro, Brazil., Sauma D; Departamento de Biología, Facultad de Ciencias, Universidad de Chile, Santiago, Chile., Moreira JCF; Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Gelain DP; Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Porciuncula LO; Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Palma V; Laboratory of Stem Cells & Developmental Biology, Departamento de Biología, Universidad de Chile, Santiago, Chile., Martins-de-Souza D; Instituto D'Or de Pesquisa e Ensino (IDOR), Rio de Janeiro, Brazil.; Departamento de Bioquímica e Biologia Tecidual, Instituto de Biologia, Universidade Estadual de Campinas, Campinas, Brazil.; Experimental Medicine Research Cluster (EMRC), University of Campinas, Campinas, SP, Brazil.; Instituto Nacional de Biomarcadores em Neuropsiquiatria (INBION), Conselho Nacional de Desenvolvimento Científico e Tecnológico, São Paulo, Brazil., Rehen SK; Instituto D'Or de Pesquisa e Ensino (IDOR), Rio de Janeiro, Brazil. stevens.rehen@idor.org.; Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil. stevens.rehen@idor.org.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2023 Feb; Vol. 28 (2), pp. 871-882. Date of Electronic Publication: 2022 Oct 24.

Schizophrenia-derived hiPSC brain microvascular endothelial-like cells show impairments in angiogenesis and blood-brain barrier function.

Autor: Casas BS; Laboratory of Stem Cells and Developmental Biology, Universidad de Chile, Santiago, Chile., Vitória G; Instituto D'Or de Pesquisa e Ensino (IDOR), Rio de Janeiro, Brazil., Prieto CP; Laboratory of Stem Cells and Developmental Biology, Universidad de Chile, Santiago, Chile., Casas M; ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile., Chacón C; ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile., Uhrig M; Centro de Medicina Regenerativa, Facultad de Medicina Clínica Alemana-Universidad del Desarrollo, Santiago, Chile., Ezquer F; Centro de Medicina Regenerativa, Facultad de Medicina Clínica Alemana-Universidad del Desarrollo, Santiago, Chile., Ezquer M; Centro de Medicina Regenerativa, Facultad de Medicina Clínica Alemana-Universidad del Desarrollo, Santiago, Chile., Rehen SK; Instituto D'Or de Pesquisa e Ensino (IDOR), Rio de Janeiro, Brazil.; Departamento de Genética, Instituto de Biología, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Palma V; Laboratory of Stem Cells and Developmental Biology, Universidad de Chile, Santiago, Chile. vpalma@uchile.cl.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2022 Sep; Vol. 27 (9), pp. 3708-3718. Date of Electronic Publication: 2022 Jun 15.

Perinatal Food Deprivation Modifies the Caloric Restriction Response in Adult Mice Through Sirt1.

Autor: Peña-Villalobos I; Department of Ecological Sciences, Faculty of Sciences, Universidad de Chile, Santiago, Chile.; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago, Chile., Otárola FA; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago, Chile., Casas BS; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago, Chile., Sabat P; Department of Ecological Sciences, Faculty of Sciences, Universidad de Chile, Santiago, Chile.; Center of Applied Ecology and Sustainability (CAPES), Santiago, Chile., Palma V; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago, Chile.

Publikováno v: Frontiers in physiology [Front Physiol] 2021 Dec 02; Vol. 12, pp. 769444. Date of Electronic Publication: 2021 Dec 02 (Print Publication: 2021).

Tumor-Derived Pericytes Driven by EGFR Mutations Govern the Vascular and Immune Microenvironment of Gliomas.

Autor: Segura-Collar B; Neurooncology Unit, Unidad Funcional de Investigación en Enfermedades Crónicas (UFIEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain., Garranzo-Asensio M; Neurooncology Unit, Unidad Funcional de Investigación en Enfermedades Crónicas (UFIEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain., Herranz B; Neurooncology Unit, Unidad Funcional de Investigación en Enfermedades Crónicas (UFIEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Facultad de Medicina, Universidad Francisco de Vitoria, Madrid, Spain., Hernández-SanMiguel E; Neurooncology Unit, Unidad Funcional de Investigación en Enfermedades Crónicas (UFIEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain., Cejalvo T; Neurooncology Unit, Unidad Funcional de Investigación en Enfermedades Crónicas (UFIEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain., Casas BS; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago, Chile., Matheu A; Cellular Oncology Group, Biodonostia Health Research Institute, San Sebastian, Spain.; IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.; CIBERFES, Instituto de Salud Carlos III, Madrid, Spain., Pérez-Núñez Á; Dto. Neurocirugía, Hospital 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain., Sepúlveda-Sánchez JM; Instituto de Investigaciones Biomédicas I+12, Hospital 12 de Octubre, Madrid, Spain., Hernández-Laín A; Instituto de Investigaciones Biomédicas I+12, Hospital 12 de Octubre, Madrid, Spain., Palma V; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago, Chile., Gargini R; Neurooncology Unit, Unidad Funcional de Investigación en Enfermedades Crónicas (UFIEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain. psanchezg@isciii.es rgargini@isciii.es., Sánchez-Gómez P; Neurooncology Unit, Unidad Funcional de Investigación en Enfermedades Crónicas (UFIEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain. psanchezg@isciii.es rgargini@isciii.es.

Publikováno v: Cancer research [Cancer Res] 2021 Apr 15; Vol. 81 (8), pp. 2142-2156. Date of Electronic Publication: 2021 Feb 16.

Downregulation of the Netrin-1 Receptor UNC5b Underlies Increased Placental Angiogenesis in Human Gestational Diabetes Mellitus.

Autor: Prieto CP; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago de Chile 7800024, Chile. cpprieto@uchile.cl., Casas BS; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago de Chile 7800024, Chile. barbara.s.casas@gmail.com., Falcón P; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago de Chile 7800024, Chile. paulina.falcon.u@gmail.com., Villanueva A; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago de Chile 7800024, Chile. andreavillanuevaarros@gmail.com., Lois P; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago de Chile 7800024, Chile. pablois@uchile.com., Lattus J; Campus Oriente, Department of Obstetrics and Gynecology, Faculty of Medicine, Universidad de Chile, Santiago de Chile 7800024, Chile. doctorjoselattus@gmail.com., Palma V; Laboratory of Stem Cells and Developmental Biology, Faculty of Sciences, Universidad de Chile, Santiago de Chile 7800024, Chile. vpalma@uchile.cl.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2019 Mar 20; Vol. 20 (6). Date of Electronic Publication: 2019 Mar 20.