Phosphodiesterase 5A inhibition decreases NHE-1 activity without altering steady state pHi: Role of phosphatases

Autor: Díaz Gómez, Andrea Romina, Nolly, Mariela Beatriz, Massarutti, Carolina, Casarini, María J., Garciarena, Carolina Denis, Ennis, Irene Lucia, Cingolani, Horacio Eugenio, Perez, Nestor Gustavo

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Background/Aims: This study aimed to identify the signaling pathway for the proposed link between phosphodiesterase-5A (PDE5A) inhibition and decreased cardiac Na + /H + exchanger (NHE-1) activity. Methods: NHE-1 activity was assessed in rat isolated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3732cc6951ceaea9255692a5a0c27afb
http://sedici.unlp.edu.ar/handle/10915/82462

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Phosphodiesterase 5A Inhibition Decreases NHE-1 Activity Without Altering Steady State pHi: Role of Phosphatases.

Autor: Díaz, Romina G., Nolly, Mariela B., Massarutti, Carolina, Casarini, María J., Garciarena, Carolina D., Ennis, Irene L., Cingolani, Horacio E., Pérez, Néstor G.

Publikováno v: Cellular Physiology & Biochemistry (Karger AG); 2010, Vol. 26 Issue 4/5, p531-540, 10p