Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Cas van den Beld"'
Autor:
Robert Huls, Walter Krauwinkel, Tom van den Berg, Cas van den Beld, Willem Niesing, John Meijer, Vincent Hofstede
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 167
Mirabegron is the first registered β3-adrenoceptor agonist for treatment of overactive bladder as an alternative to antimuscarinics. Previously four liquid chromatography-tandem mass spectrometry assays were published to determine mirabegron and eig
Publikováno v:
Analytical biochemistry. 559
The aim of this work was to assess the influence of preanalytical variables on the stability of two endogenous opioid peptides (Methionine-Enkephalin and Leucine-Enkephalin) in human plasma. For this purpose, first a sensitive LC-MS/MS analytical met
Publikováno v:
Bioanalysis. 9(24)
In regulated bioanalysis, the acceptance of results is batch-wise. When during clinical development derived pharmacokinetic or pharmacodynamic results from different studies will be combined or compared, it is recommendable to monitor the long-term r
Autor:
Raymond van Teijlingen, Shin Takusagawa, Takashi Usui, Marcel van Gelderen, Cas van den Beld, John Meijer
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
Mirabegron is being developed for the treatment of overactive bladder. To support the development of mirabegron, including pharmacokinetic studies, liquid chromatography/tandem mass spectrometry methods for mirabegron and eight metabolites (M5, M8, M
Autor:
Klick, Silke1 Silke.Klick@astrazeneca.com, Muijselaar, Pim G.2, Waterval, Joop3 Joop.Waterval@organon.com, Eichinger, Thomas4, Korn, Christian5, Gerding, Thijs K.6, Debets, Alexander J.7, de Griend, Cari Sänger-van8, van den Beld, Cas9, Somsen, Govert W.10,11, de Jong, Gerhardus J.
Publikováno v:
Pharmaceutical Technology. Feb2005, Vol. 29 Issue 2, p48-66. 10p.