Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Carys Morgan"'
Autor:
Mairéad G. McNamara, Jayne Swain, Zoe Craig, Rohini Sharma, Olusola Faluyi, Jonathan Wadsley, Carys Morgan, Lucy R. Wall, Ian Chau, Nick Reed, Debashis Sarker, Jane Margetts, Daniel Krell, Judith Cave, Sharmila Sothi, Alan Anthoney, Christopher Bell, Alkesh Patel, Jamie B. Oughton, David A. Cairns, Wasat Mansoor, Angela Lamarca, Richard A. Hubner, Juan W. Valle
Publikováno v:
EClinicalMedicine, Vol 60, Iss , Pp 102015- (2023)
Summary: Background: The prognosis for patients with poorly-differentiated extra-pulmonary neuroendocrine carcinoma (PD-EP-NEC) is poor. A recognised first-line (1L) treatment for advanced disease is etoposide/platinum-based chemotherapy with no stan
Externí odkaz:
https://doaj.org/article/17e61c62deeb4eef9d3d7c4b9df3c376
Autor:
Emma E Vincent, Douglas J E Elder, Linda O'Flaherty, Olivier E Pardo, Piotr Dzien, Lois Phillips, Carys Morgan, Joya Pawade, Margaret T May, Muhammad Sohail, Martin R Hetzel, Michael J Seckl, Jeremy M Tavaré
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114725 (2014)
Glycogen synthase kinase 3 (GSK3) is a central regulator of cellular metabolism, development and growth. GSK3 activity was thought to oppose tumourigenesis, yet recent studies indicate that it may support tumour growth in some cancer types including
Externí odkaz:
https://doaj.org/article/e50111a30fc64073850e7a917f9519fe
Autor:
Manish A. Shah, Anghel Adrian Udrea, Igor Bondarenko, Was Mansoor, Raquel Guardeño Sánchez, Tomasz Sarosiek, Silvia Bozzarelli, Michael Schenker, Carlos Gomez-Martin, Carys Morgan, Mustafa Özgüroğlu, Joanna Pikiel, Haralabos P. Kalofonos, Elzbieta Wojcik, Tomas Buchler, Daniel Swinson, Irfan Cicin, Mano Joseph, Ihor Vynnychenko, Alexander Valerievich Luft, Peter C. Enzinger, Tomas Salek, Christos Papandreou, Christophe Tournigand, Evaristo Maiello, Ran Wei, David Ferry, Ling Gao, Joana M. Oliveira, Jaffer A. Ajani
Publikováno v:
Cancers; Volume 14; Issue 5; Pages: 1168
Studies JVDB and JVCZ examined alternative ramucirumab dosing regimens as monotherapy or combined with paclitaxel, respectively, in patients with advanced/metastatic gastric/gastroesophageal junction (GEJ) adenocarcinoma. For JVDB, randomized patient
Chapter 7 discusses oesophageal tumours, including clinical background, diagnosis and staging, planning, therapeutic assessment, and follow-up. Patients with oesophageal cancer have a poor prognosis because many present with advanced disease. Accurat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9bd4306b66107c3721ef0b577bcd364
https://doi.org/10.1093/med/9780198818502.003.0007
https://doi.org/10.1093/med/9780198818502.003.0007
Autor:
Zoe Craig, Jayne Swain, Rohini Sharma, Olusola Olusesan Faluyi, Jonathan Wadsley, Carys Morgan, Lucy R. Wall, Ian Chau, Nicholas Simon Reed, Debashis Sarker, Jane Margetts, Daniel Krell, Judith Cave, Sothi Sharmila, Alan Anthoney, Alkesh Patel, Angela Lamarca, Richard A Hubner, Juan W. Valle, Mairead Geraldine McNamara
Publikováno v:
Journal of Clinical Oncology. 40:293-293
293 Background: NET-02 was a multi-centre, randomised (1:1), non-comparative phase II trial of nal-IRI/5-FU/folinic acid (ARM A) or docetaxel (ARM B) in pts with progressive PD-EP-NEC, aimed at selecting a treatment for evaluation in a phase III tria
Publikováno v:
Treatment of Cancer ISBN: 9780429026638
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4da9585d65714f09b507ae06ae9437e
https://doi.org/10.1201/9780429026638-8
https://doi.org/10.1201/9780429026638-8
Autor:
Naureen Starling, Sheela Rao, Elli Bourmpaki, Bijal Patel, Thomas K. Waddell, Catherine Cafferkey, Caroline Fong, David Cunningham, Michael Davidson, Ian Chau, David Watkins, Gayathri Anandappa, Charlotte Rees, Fareeda Y. Coxon, Clare Peckitt, Carys Morgan, Tom Roques, Jonathan Wadsley, Katharina von Loga, Ruwaida Begum
Publikováno v:
Journal of Clinical Oncology. 39:4015-4015
4015 Background: PLATFORM is a prospective, open-label, multicentre, adaptive phase II trial assessing maintenance therapy in patients (pts) with OG adenocarcinoma after platinum-based first-line induction chemotherapy. HER2 negative pts were initial
Autor:
Russell D. Petty, Ruwaida Begum, Bijal Patel, Madeleine Hewish, Jonathan Wadsley, Katharina von Loga, Andrea Turner, Ian Chau, Michael Davidson, Catherine Cafferkey, David Cunningham, Fareeda Y. Coxon, Caroline Fong, Thomas K. Waddell, Gayathri Anandappa, Naureen Starling, Marlon Rebelatto, Carys Morgan, Tom Roques, Clare Peckitt
Publikováno v:
Journal of Clinical Oncology. 38:282-282
282 Background: Advanced OGA patients (pts) are treated with platinum-based 1st line chemotherapy but the role of maintenance therapy once disease control is obtained is unknown. Methods: PLATFORM is a prospective, open-label, adaptive phase II trial
Autor:
Mark Reynolds, Catherine Powell, Dafydd Aled Rees, Rebecca Hopps, Mohid S. Khan, Carole Bell, Carys Morgan, Adam Christian, Sarah Gwynne
Publikováno v:
Gastroenterology Service.
Introduction Requiring many specialities, NETs have complex pathways presenting a challenge to plan services in existing NHS structures. In Wales, we aimed to produce patient-centred services for Neuroendocrine Tumours (NETs) incorporating the additi
Publikováno v:
The Lancet Oncology. 12:806-814
Chemotherapy can induce various clinical emergencies. Prompt recognition and management of these adverse events are important for avoiding further morbidity and mortality. Some events such as hypersensitivity and extravasation are quite common, where