Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Caryn L. Elsegood"'
Autor:
Joaquín Fernández-Irigoyen, Sarah B. McSpadden, Luke A. Diepeveen, Janina E.E. Tirnitz-Parker, Alfredo Martínez, Bernard A. Callus, Weihao Zhao, Enrique Santamaría, Caryn L. Elsegood, Hyerin Park, Ken H. Woo, Andy Chevigné, Adam M. Passman, Laura Ochoa-Callejero, Roslyn London, George C.T. Yeoh, José Ramón Blanco, Martyna Szpakowska, Robyn P. Strauss, Laura Medina-Ruiz, Megan Finch-Edmondson, Rodrigo Carlessi, Murray V. Baker, Neil Andrewartha
Publikováno v:
RIUR. Repositorio Institucional de la Universidad de La Rioja
instname
Cancers, Vol 13, Iss 4935, p 4935 (2021)
Cancers
Volume 13
Issue 19
Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
instname
Cancers, Vol 13, Iss 4935, p 4935 (2021)
Cancers
Volume 13
Issue 19
Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
Maraviroc (MVC), a CCR5 antagonist, reduces liver fibrosis, injury and tumour burden in mice fed a hepatocarcinogenic diet, suggesting it has potential as a cancer therapeutic. We investigated the effect of MVC on liver progenitor cells (LPCs) and ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba21101ccb47614a9abb1a1143a5339
https://hdl.handle.net/2454/42707
https://hdl.handle.net/2454/42707
Autor:
Anne S. Kramer, Geoffrey J. Laurent, George C.T. Yeoh, Lingjun Mou, Caryn L. Elsegood, Bruce Latham, Luke A. Diepeveen, Laura Ochoa-Callejero
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Hepatic progenitor cells (HPCs) play an important regenerative role in acute and chronic liver pathologies. Liver disease research often necessitates the grading of disease severity, and pathologists’ reports are the current gold-standard for asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6229ca281f46dea74b9041b066e2cb5
http://link.springer.com/article/10.1038/s41598-018-21757-4
http://link.springer.com/article/10.1038/s41598-018-21757-4
Autor:
Gregory Miller, Candice Alexandra Grzelak, John K. Olynyk, Julia Köhn-Gaone, Geoffrey W. McCaughan, Grant A. Ramm, Nicholas A. Shackel, Caryn L. Elsegood, Benjamin J. Dwyer, Janina E.E. Tirnitz-Parker
Publikováno v:
The American Journal of Pathology. 186:1762-1774
Complications of end-stage chronic liver disease signify a major cause of mortality worldwide. Irrespective of the underlying cause, most chronic liver diseases are characterized by hepatocellular necrosis, inflammation, fibrosis, and proliferation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec3f412dfa0a6dee3ac8bd61ccfe02cb
https://doi.org/10.1016/j.ajpath.2016.03.005
https://doi.org/10.1016/j.ajpath.2016.03.005
Autor:
Geoffrey W. McCaughan, John K. Olynyk, Janina E.E. Tirnitz-Parker, Corey Giles, Grant A. Ramm, Caryn L. Elsegood, Julia Köhn-Gaone, Jully Gogoi-Tiwari, Dirk Schmidt-Arras, Francis D. Gratte
Publikováno v:
Journal of visualized experiments : JoVE. (128)
Chronic liver diseases, such as viral hepatitis, alcoholic liver disease, or non-alcoholic fatty liver disease, are characterized by continual inflammation, progressive destruction and regeneration of the hepatic parenchyma, liver progenitor cell pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f08b13885c519573ed01edbdf0bb63
https://pubmed.ncbi.nlm.nih.gov/29155718
https://pubmed.ncbi.nlm.nih.gov/29155718
Autor:
Janina E.E. Tirnitz-Parker, Geraldine Kong, Adam M. Passman, Benjamin J. Dwyer, George C.T. Yeoh, Sing Yee Yeung, Bernard A. Callus, Lawrence J. Abraham, Ken Woo, Sven S. Kampmann, Caryn L. Elsegood, Luke A. Diepeveen, Scott G. Stewart, Megan Finch-Edmondson, John K. Olynyk
Publikováno v:
European journal of medicinal chemistry. 120
Background & aims The availability of non-tumorigenic and tumorigenic liver progenitor cell (LPC) lines affords a method to screen putative anti-liver cancer agents to identify those that are selectively effective. To prove this principle we tested t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8193d69df00e3653e64461b8cf7dcb3
https://pubmed.ncbi.nlm.nih.gov/27208658
https://pubmed.ncbi.nlm.nih.gov/27208658
Autor:
Alice Domenichini, Mariapia A. Degli-Esposti, Nico van Rooijen, Chun Wei Chan, George C.T. Yeoh, Caryn L. Elsegood, Matthew E. Wikstrom, John K. Olynyk, Ruth Ganss, Kyren A. Lazarus
Publikováno v:
Elsegood, C L, Chan, C W, Degli-Esposti, M A, Wikstrom, M E, Domenichini, A, Lazarus, K, van Rooijen, N, Ganss, R, Olynyk, J K & Yeoh, G C T 2015, ' Kupffer cell-monocyte communication is essential for initiating murine liver progenitor cell-mediated liver regeneration ', Hepatology, vol. 62, no. 4, pp. 1272-1284 . https://doi.org/10.1002/hep.27977
Hepatology, 62(4), 1272-1284. John Wiley and Sons Ltd
Hepatology, 62(4), 1272-1284. John Wiley and Sons Ltd
Liver progenitor cells (LPCs) are necessary for repair in chronic liver disease because the remaining hepatocytes cannot replicate. However, LPC numbers also correlate with disease severity and hepatocellular carcinoma risk. Thus, the progenitor cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38fefc385f4b36f39efaf85377ac0fab
https://research.vumc.nl/en/publications/2628e1a9-d481-4737-9c26-9f6b8e5a749a
https://research.vumc.nl/en/publications/2628e1a9-d481-4737-9c26-9f6b8e5a749a
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 38:1518-1529
The macrophage colony stimulating factor receptor (cFms) and alpha(V)beta(3) integrin are both abundantly expressed and play critical roles in the differentiation, survival and migration of osteoclasts. We have previously demonstrated that cross-talk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f98654dde57036fb2a1c896238f2c4f
https://doi.org/10.1016/j.biocel.2006.02.011
https://doi.org/10.1016/j.biocel.2006.02.011
Publikováno v:
Clinical & Translational Immunology
The global prevalence of liver cancer is rapidly rising, mostly as a result of the amplified incidence rates of viral hepatitis, alcohol abuse and obesity in recent decades. Treatment options for liver cancer are remarkably limited with sorafenib bei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9859551b89654c77b388e280fede6518
http://europepmc.org/articles/PMC5704099
http://europepmc.org/articles/PMC5704099
Autor:
Melanie Voevodin, Spencer D. Proctor, John C.L. Mamo, Darrin Smith, Donna F. Vine, Caryn L. Elsegood, Kenneth C.-W. Yu, Hanni C. Gennat
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 24:288-293
SUMMARY 1. Atherosclerosis begins with the deposition of cholesterol in arterial tissue that is thought to be derived from circulating lipoproteins. There is considerable evidence implicating low density lipoprotein (LDL) as a primary source of plaqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f0cab5431e04dc31fe84e22708d75c4
https://doi.org/10.1111/j.1440-1681.1997.tb01822.x
https://doi.org/10.1111/j.1440-1681.1997.tb01822.x
Publikováno v:
Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 13:231-239
Probucol was given to rats made diabetic by streptozotocin. Compared with diabetic rats not receiving probucol or with nondiabetic rats, probucol lowered the plasma concentrations of triglycerides, phospholipids, cholesterol, and apolipoprotein B. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c5afaa6c15ef82bff7ab4e51d2320b
https://doi.org/10.1161/01.atv.13.2.231
https://doi.org/10.1161/01.atv.13.2.231