Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Caryn Cloer"'
Autor:
Caryn Cloer, Laila Roudsari, Lauren Rochelle, Timothy Petrie, Michaela Welch, Joseph Charest, Kelly Tan, Li Fugang, Thomas Petersen, Roger Ilagan, Sarah Hogan
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Mesenchymal stem cell derived extracellular vesicles (MSC-EVs) are bioactive particles that evoke beneficial responses in recipient cells. We identified a role for MSC-EV in immune modulation and cellular salvage in a model of SARS-CoV-2 induced acut
Externí odkaz:
https://doaj.org/article/c96ccb35f14f4e1db9e634676aa3eb8d
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19906 (2011)
Antisense therapy has recently been demonstrated with great potential for targeted exon skipping and restoration of dystrophin production in cultured muscle cells and in muscles of Duchenne Muscular Dystrophy (DMD) patients. Therapeutic values of exo
Externí odkaz:
https://doaj.org/article/ec86ca99629443aea1ab568801304cff
Autor:
Roger M. Ilagan, Sarah Hogan, Lauren Rochelle, Michaela Welch, Caryn Cloer, Kelly Tan, Laila Roudsari, Thomas Petersen, Joseph L. Charest, Li Fugang, Timothy Petrie
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0259732 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11, p e0259732 (2021)
PLoS ONE
Mesenchymal stem cell derived extracellular vesicles (MSC-EVs) are bioactive particles that evoke beneficial responses in recipient cells. We identified a role for MSC-EV in immune modulation and cellular salvage in a model of SARS-CoV-2 induced acut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb09cb88a556d7e96d53757ea74de2d6
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592477/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592477/?tool=EBI
Autor:
Stephanie Milazi, Caryn Cloer, Qi Long Lu, Bo Wu, Hong M. Moulton, Pei J. Lu, Mona Shaban, Sapana N. Shah, L Marston-Poe
Publikováno v:
Gene Therapy. 21:785-793
Antisense therapy with both chemistries of phosphorodiamidate morpholino oligomers (PMOs) and 2'-O-methyl phosphorothioate has demonstrated the capability to induce dystrophin expression in Duchenne muscular dystrophy (DMD) patients in phase II-III c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a520d9b090eedbd6f8d73098a82e2aa2
https://doi.org/10.1038/gt.2014.53
https://doi.org/10.1038/gt.2014.53
Publikováno v:
Human Gene Therapy. 25:419-427
Hyperbranched poly(ester amine)s (PEAs) based on tris[2-(acryloyloxy)ethyl]isocyanurate (TAEI) cross-linked low-molecular-weight polyethylenimine (Mw: 0.8k/1.2k/2.0k) have been evaluated for delivering antisense phosphorodiamidate morpholino oligomer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc40d27b4c668024dad0c22351ede7a3
https://doi.org/10.1089/hum.2013.156
https://doi.org/10.1089/hum.2013.156
Autor:
Ming O. Li, Ben Youngblood, Rigel J. Kishton, Cliff Guy, Jeffrey C. Rathmell, Scott A. Brown, Xia Gao, Sharad Shrestha, Hu Zeng, Jason W. Locasale, Sivan Cohen, Mytrang H. Do, Geoffrey Neale, Hongbo Chi, Caryn Cloer
Publikováno v:
Immunity. 45(3)
Summary Follicular helper T (Tfh) cells are crucial for germinal center (GC) formation and humoral adaptive immunity. Mechanisms underlying Tfh cell differentiation in peripheral and mucosal lymphoid organs are incompletely understood. We report here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e57e76a2b44886fe2768741fae25c3
https://pubmed.ncbi.nlm.nih.gov/27637146
https://pubmed.ncbi.nlm.nih.gov/27637146
Publikováno v:
Nature
The mechanistic target of rapamycin (mTOR) pathway integrates diverse environmental inputs, including immune signals and metabolic cues, to direct T-cell fate decisions. The activation of mTOR, which is the catalytic subunit of the mTORC1 and mTORC2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875575169b186b4f9c5077e31f6e756b
https://pubmed.ncbi.nlm.nih.gov/23812589
https://pubmed.ncbi.nlm.nih.gov/23812589
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 21(1)
We investigated a series of small-sized polyethylenimine (PEI, 0.8/1.2 k)-conjugated pluronic copolymers (PCMs) for their potential to enhance delivery of an antisense phosphorodiamidate morpholino oligomer (PMO) in vitro and in dystrophic mdx mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512f18c32aac452949ac88cddcd835af
https://pubmed.ncbi.nlm.nih.gov/23164938
https://pubmed.ncbi.nlm.nih.gov/23164938
Autor:
Stephanie Milazi, Mona Shaban, Qi Long Lu, Sapana N. Shah, Snimar Grewal, Peijuan Lu, Hong M. Moulton, Bo Wu, Caryn Cloer
Exon skipping is capable of correcting frameshift and nonsense mutations in Duchenne muscular dystrophy. Phase 2 clinical trials in the United Kingdom and the Netherlands have reported induction of dystrophin expression in muscle of Duchenne muscular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b62952468eba99585fb149f71a78991
https://europepmc.org/articles/PMC3409432/
https://europepmc.org/articles/PMC3409432/
Publikováno v:
Bioconjugate chemistry. 23(4)
Hyperbranched poly(ester amine)s (PEAs) were successfully synthesized by Michael addition reaction between tris[2-(acryloyloxy)ethyl]isocyanurate (TAEI) and low-molecular-weight polyethylenimine (LPEI, M(w) 0.8k, 1.2k, and 2.0k) and evaluated in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33bfb3c56d4c9f6806203a92fff734be
https://pubmed.ncbi.nlm.nih.gov/22443086
https://pubmed.ncbi.nlm.nih.gov/22443086