Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Caryl L. Meade"'
Autor:
Weijun Ma, Aaron M. D’Antona, Caryl L. Meade, Xiaotian Zhong, Jing Zhou, Ashley Schwab, Laura Lin, William S. Somers
Publikováno v:
Therapeutic Antibodies ISBN: 9781071614495
Large-scale transient expression in Chinese Hamster Ovary (CHO) cells provides a rapid protein production method with a potential start-to-end alignment advantage for biotherapeutics drug discovery. In this chapter, experimental protocols are illustr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c40f2d060234af827155c94db561a629
https://doi.org/10.1007/978-1-0716-1450-1_7
https://doi.org/10.1007/978-1-0716-1450-1_7
Autor:
Xiaotian, Zhong, Ashley, Schwab, Weijun, Ma, Caryl L, Meade, Jing, Zhou, Aaron M, D'Antona, Will, Somers, Laura, Lin
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2313
Large-scale transient expression in Chinese Hamster Ovary (CHO) cells provides a rapid protein production method with a potential start-to-end alignment advantage for biotherapeutics drug discovery. In this chapter, experimental protocols are illustr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7abed16fbc9eb59eaf3cc664a67006fd
https://pubmed.ncbi.nlm.nih.gov/34478135
https://pubmed.ncbi.nlm.nih.gov/34478135
Autor:
Orla Cunningham, Eric Sousa, Susan Benard, Yongjing Guo, C.M. Francis, Puja Sapra, Laura Lin, Lindsay King, Fang Jin, Weijun Ma, Aaron M. D’Antona, Nicole Piche-Nicholas, Sinead E. Keating, Sara Hanscom, Gurkan Guntas, Wayne Stochaj, Khetemcnee Lam, Claire Hendershot, Liliana Wroblewska, H. Lily Zhu, Kimberly Ann Marquette, Kristine Svenson, Divya Mathur, Fernando Narciandi, Yan Liu, Weili Duan, Edward R. Lavallie, Alison Betts, Rosemary Lawrence-Henderson, Chang Chew Shun, Adam Root, Maya Arai, Madan Katragadda, Amy King, Amy Tam, Jatin Narula, Jason Wade, Kerry Kelleher, Lioudmila Tchistiakova, Lidia Mosyak, Alfredo Darmanin Sheehan, Han Yang, Yan Zhang, James R. Apgar, Edward Rosfjord, Laird Bloom, Caryl L. Meade, Matthew McKenna
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
We report here the discovery and optimization of a novel T cell retargeting anti-GUCY2C x anti-CD3ε bispecific antibody for the treatment of solid tumors. Using a combination of hybridoma, phage display and rational design protein engineering, we ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c6dd5658cfd24d66b5b31b6d32bf8c
https://pubmed.ncbi.nlm.nih.gov/33459147
https://pubmed.ncbi.nlm.nih.gov/33459147
Autor:
Khetemenee Lam, Richard J. Cornell, Aaron M. D’Antona, Eliza Llewellyn, Ron Kriz, Jeffrey K. Marshall, Evan R. Mahan, Hongli L. Zhu, Weijun Ma, Bruno Figueroa, Annette Sievers, Xiaotian Zhong, C.M. Francis, Boriana Tzvetkova, Dana DiNino, Amy Tam, William S. Somers, Christopher Lee, Jane Guo, Richard Zollner, John J. Scarcelli, Laura Lin, Kaffa Cote, Caryl L. Meade
Publikováno v:
Biotechnology Progress. 35:e2724
Large-scale transient expression in mammalian cells is a rapid protein production technology often used to shorten overall timelines for biotherapeutics drug discovery. In this study we demonstrate transient expression in a Chinese hamster ovary (CHO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440fd7837885b71e50f94a85c80fd5f4
https://doi.org/10.1002/btpr.2724
https://doi.org/10.1002/btpr.2724
Autor:
Kristine Svenson, Ezio Bonvini, Alfredo Darmanin Sheehan, William J.J. Finlay, Paul A. Moore, Jocelyn Sanford, Chad May, Kelvin M. Kerns, Liqin Liu, Susan Benard, Aaron M. D’Antona, Steve Burke, Scott Gatto, Hua Li, Syd Johnson, Hans-Peter Gerber, Yinhua Yang, Edward R. Lavallie, Gurunadh Reddy Chichili, Lioudmila Tchistiakova, Tao He, Peter LaPan, Stephane Olland, William Brady, Khetemenee Lam, Cliona M. O'Sullivan, Wei Cao, Laura Lin, Adam Root, William S. Somers, Bilian Li, Ralph Alderson, Macy Jin, Lisa Racie, Lily Zhu, Weijun Ma, Caryl L. Meade, Lidia Mosyak, Wayne Stochaj, Amy King, Emma Cummins, Matthew Allister Lambert, Laird Bloom, Dianah Barrett, James R. Apgar, Maya Arai
Publikováno v:
Antibodies, Vol 5, Iss 1, p 6 (2016)
Antibodies; Volume 5; Issue 1; Pages: 6
Antibodies
Antibodies; Volume 5; Issue 1; Pages: 6
Antibodies
Bispecific antibodies offer a promising approach for the treatment of cancer but can be challenging to engineer and manufacture. Here we report the development of PF-06671008, an extended-half-life dual-affinity re-targeting (DART®) bispecific molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5727dc94b5642ceafb627d901f3b8117
https://doi.org/10.3390/antib5010006
https://doi.org/10.3390/antib5010006
Autor:
Nathan D. Pfeifer, Muhammed F. Hashim, William R. Tschantz, Ajith V. Kamath, Anthony J. Lanzetti, Caryl L. Meade, Françoise Berlioz-Seux, Leyu Wang
Publikováno v:
Protein expression and purification. 57(2)
OATP2B1 is an important member of the organic anion transporting polypeptides (OATP) family and is implicated in the intestinal and hepatic disposition of endo- and xenobiotics. The purpose of this work was to produce a highly purified protein for us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be639195b9cc5d31ab5637eea9caaf9
https://pubmed.ncbi.nlm.nih.gov/18024077
https://pubmed.ncbi.nlm.nih.gov/18024077