Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Caryl L. Amrick"'
Autor:
Caryl L. Amrick, Stephen L. Rovinski, Francis John E, James L. Hyun, Robert Neale, D. Wilson, P. S. Loo, Deborah Murphy, Debra A. Bennett
Publikováno v:
ChemInform. 23
Modification of the benzodiazepine (BZ) receptor binding template 2-aryl[1,2,4]triazolo[1,5-c]quinazolin-5(6H)-one by replacement of the annelated benzene ring with various alicyclic and heterocyclic moieties led to novel structures with potent BZ re
Autor:
P. S. Loo, James L. Hyun, Debra A. Bennett, Francis John E, D. Wilson, Robert Neale, Caryl L. Amrick, Deborah Murphy, Stephen L. Rovinski
Publikováno v:
Journal of Medicinal Chemistry. 34:2899-2906
Modification of the benzodiazepine (BZ) receptor binding template 2-aryl[1,2,4]triazolo[1,5-c]quinazolin-5(6H)-one by replacement of the annelated benzene ring with various alicyclic and heterocyclic moieties led to novel structures with potent BZ re
Publikováno v:
Life Sciences. 42:447-454
The PCP-like compounds ketamine and dexoxadrol were evaluated in two behavioral test procedures known to be sensitive to competitive N-methyl-D-aspartate (NMDA) receptor antagonists. In the NMDA-induced convulsion test in mice, ketamine and dexoxadro
Autor:
Caryl L. Amrick, Debra A. Bennett
Publikováno v:
Life Sciences. 40:585-591
Male Sprague Dawley rats were trained to discriminate an interoceptive effect associated with a subconvulsant dose (30 mg/kg i.p.) of the excitatory amino acid receptor agonist, N-methyl-D-aspartate (NMDA). Approximately 60% of the rats learned to di
Autor:
Caryl L. Amrick, Debra A. Bennett
Publikováno v:
Life Sciences. 39:2455-2461
The N-methyl-D-aspartate (NMDA) receptor antagonist, AP7, was evaluated in two animal test procedures known to be sensitive to the effects of diazepam. In rats trained to discriminate diazepam from vehicle, AP7 produced dose-dependent generalization
Autor:
P.S. Bernard, Susan Gerhardt, Patricia Loo, Jeffrey M. Liebman, Naokata Yokoyama, Caryl L. Amrick, Carl A. Boast, Markus Schmutz, Albert Braunwalder, D. Wilson, Debra A. Bennett, Klaus Klebs
Publikováno v:
Drug Development Research. 11:219-233
CGS 17867A (2-(4-chlorophenyl)-2,5,6,7,8,9,-hexahydor-3H-pyrazolo [4,3,-c]quinoline-3-one-hydrochloride salt) is a tetrahydorpyrazoloquinoline related to the benzodiazepine (BZ) receptor agonist, CGS 9896. The compound is an effective inhibitor of [3
Autor:
Caryl L. Amrick, Jeffrey M. Liebman, Naokata Yokoyama, Debra A. Bennett, P.S. Bernard, D. Wilson
Publikováno v:
Drug Development Research. 6:313-325
CGS 9895 is a pyrazoloquinoline closely related to the benzodiazepine agonist CGS 9896 and the benzodiazepine antagonist CGS 8216. In anxiolytic test procedures, this compound generalizes to CGS 9896 discriminative stimuli, produces an increase in pu
Autor:
Bennett, Debra A., Amrick, Caryl L., Wilson, Douglas E., Boast, Carl A., Loo, Patricia, Bernard, Patrick S., Schmutz, Markus, Gerhardt, Susan C., Braunwalder, Albert, Klebs, Klaus, Yokoyama, Naokata, Liebman, Jeffrey M.
Publikováno v:
Drug Development Research; 1987, Vol. 11 Issue 3/4, p219-233, 15p
Autor:
Bennett, Debra A., Amrick, Caryl L., Wilson, Douglas E., Bernard, Patrick S., Yokoyama, Naokata, Liebman, Jeffrey M.
Publikováno v:
Drug Development Research; 1985, Vol. 6 Issue 4, p313-325, 13p