Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Cary DeWitte"'
Publikováno v:
Nutraceuticals, Vol 3, Iss 1, Pp 165-174 (2023)
TRPA1-related drugs alter sensation, particularly in conditions of inflammation. To further characterize the role of these drugs in bladder sensation, the TRPA1 agonist cinnamaldehyde (CMA) and oral true cinnamon spice were examined in preclinical mo
Externí odkaz:
https://doaj.org/article/98cb7ca098cd413da8afa40bed86923a
Publikováno v:
BMC Urology, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Baclofen, a clinically available GABAB receptor agonist, produces non-opioid analgesia in multiple models of pain but has not been tested for effects on bladder nociception. Methods A series of experiments examined the effects of
Externí odkaz:
https://doaj.org/article/d5c0ed06215844f98dba441dd441e691
Autor:
Timothy J. Ness, Cary DeWitte, Jennifer J. DeBerry, Morgan P. Hart, Buffie Clodfelder-Miller, Jianguo G. Gu, Jennifer Ling, Alan Randich
Publikováno v:
Frontiers in Pain Research, Vol 2 (2021)
This report describes methodological and exploratory investigations of the zymosan-induced neonatal bladder inflammation (NBI) model of interstitial cystitis/bladder pain syndrome (IC/BPS) in female rats. These results validate and extend the current
Externí odkaz:
https://doaj.org/article/4a316e54200f40fc9879f19edc02f464
Autor:
Saurabh Aggarwal, Jennifer J. DeBerry, Israr Ahmad, Prichard Lynn, Cary Dewitte, Simran Malik, Jessica S. Merlin, Burel R. Goodin, Sonya L. Heath, Sadis Matalon
Publikováno v:
Redox Biology, Vol 36, Iss , Pp 101684- (2020)
The prevalence of chronic widespread pain (CWP) in people with HIV is high, yet the underlying mechanisms are elusive. Leukocytes synthesize the endogenous opioid, β-endorphin, within their endoplasmic reticulum (ER). When released into plasma, β-e
Externí odkaz:
https://doaj.org/article/4f0a882aa5924651b2a72800103e8c6f
Publikováno v:
The journal of pain. 23(12)
The spinal mechanisms of visceral hypersensitivity are poorly understood, particularly when there is an interaction with somatic systems. Recently we demonstrated that rats which were pretreated with neonatal bladder inflammation (NBI) and subsequent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b14d05149d900713600645c7edab10
https://pubmed.ncbi.nlm.nih.gov/36089237
https://pubmed.ncbi.nlm.nih.gov/36089237
Publikováno v:
Neurosci Lett
In rodent models, conditioning with acute footshock (AFS) has been demonstrated to produce bladder hypersensitivity which is more robust when rats, tested as adults, had also been pretreated with neonatal bladder inflammation (NBI). The spinal neuroc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5527f511c7a3929a0712ef3c38098f
https://pubmed.ncbi.nlm.nih.gov/35390467
https://pubmed.ncbi.nlm.nih.gov/35390467
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e962ad8075088937e302407b5704e1e8
https://doi.org/10.2139/ssrn.4030439
https://doi.org/10.2139/ssrn.4030439
Publikováno v:
Neuropharmacology. 224:109369
Corticotropin releasing factor (CRF) receptors have been implicated in stress-induced hyperalgesia. The present study examined the role of CRF receptors Type 12 (CRFR1, CRFR2) in stress-induced bladder hyperalgesia in female rats by quantifying chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384d0ef043eb1b1e7a02e9ffbb3c6f65
https://doi.org/10.1016/j.neuropharm.2022.109369
https://doi.org/10.1016/j.neuropharm.2022.109369
Publikováno v:
Neurosci Lett
Psychological stress has been demonstrated to increase reports of pain in humans with pelvic pain of urologic origin. In rodent models, conditioning with acute footshock (AFS) has been demonstrated to increase measures of stress/anxiety as well as bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5040d6454547be0544447531ea13689b
https://pubmed.ncbi.nlm.nih.gov/34929317
https://pubmed.ncbi.nlm.nih.gov/34929317
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8a7111ca31e41301a87a9336a8ef021
https://doi.org/10.2139/ssrn.3969649
https://doi.org/10.2139/ssrn.3969649