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Liver-specific Mettl14 deletion induces nuclear heterotypia and dysregulates RNA export machinery.

Autor: Berggren KA; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Sinha S; Department of Medicine, Weill Cornell Medicine, NY, USA., Lin AE; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Schwoerer MP; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Maya S; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Biswas A; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.; Research Computing, Office of Information Technology, Princeton University, Princeton, NJ, 08544, USA., Cafiero TR; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Liu Y; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Gertje HP; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, 02118, USA., Suzuki S; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Berneshawi AR; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Carver S; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Heller B; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Hassan N; Department of Medicine, Weill Cornell Medicine, NY, USA., Ali Q; Department of Medicine, Weill Cornell Medicine, NY, USA., Beard D; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Wang D; Department of Chemistry, Princeton University, Princeton, NJ 08544, USA., Cullen JM; Department of Population Health and Pathobiology, North Carolina State University College of Veterinary Medicine, Raleigh, NC 27607, USA., Kleiner RE; Department of Chemistry, Princeton University, Princeton, NJ 08544, USA., Crossland NA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, 02118, USA.; Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 02118, USA., Schwartz RE; Department of Medicine, Weill Cornell Medicine, NY, USA.; Department of Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, NY, USA.; Department of Biomedical Engineering, Cornell University, Ithaca, NY, USA., Ploss A; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 17. Date of Electronic Publication: 2024 Jun 17.